Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for Neuroscience

Cat.No. 产品名称 Information
GC12541 Bilobalide
白果内酯; (-)-Bilobalide
A neuroprotective natural product
GC14491 B-HT 920
盐酸他利克索,Domin; Talipexole dihydrochloride
A potent agonist of D₂ receptors
GC14518 Asenapine hydrochloride
阿塞那平盐酸盐
Asenapine hydrochloride 是一种抗精神病药，是一种 5-HT (1A, 1B, 2A, 2B, 2C, 5A, 6, 7) 和多巴胺 (D2, D3, D4) 受体拮抗剂，Ki 值为 0.03-4.0 nM，作用 5- HT 和多巴胺受体分别为 1.3、0.42、1.1 nM。
GC13164 Ampalex
安帕来斯; BDP 12
An AMPA receptor modulator
GC11166 Alosetron Hydrochloride
盐酸阿洛司琼,GR 68755C;GR 68755;GR 68755X;Lotronex;GR-68755;GR68755
A 5-HT₃ receptor antagonist
GC13654 Alosetron
阿洛司琼; GR 68755; GR 68755X
A 5-HT₃ receptor antagonist
GC14916 Acamprosate calcium
阿坎酸钙,Calcium N-acetylhomotaurinate; Campral EC
An NMDA modulator
GC15014 A-867744
4-[5-(4-氯苯基)-2-甲基-3-丙酰基吡咯-1-基]苯磺酰胺,A 867744;A867744
A positive allosteric modulator of α7 nAChRs
GC11842 A-740003
N-[1-[[(氰基氨基)(5-喹啉亚氨基)甲基]氨基]-2,2-二甲基丙基]-3,4-二甲氧基苯乙酰胺,A 740003;A740003
A selective P2X₇ antagonist
GC17921 Tolcapone
托卡朋; Ro 40-7592
A reversible COMT inhibitor
GC11703 Moclobemide (Ro 111163)
吗氯贝胺; Ro111163
An Analytical Reference Standard
GC12801 Rasagiline Mesylate
甲磺酸雷沙吉兰; (R)-AGN1135 mesylate; TVP1012 mesylate
An inhibitor of MAO-B
GC16149 Topiramate
托吡酯; McN 4853; RWJ 17021
An anticonvulsant
GC17791 LY2811376
(4S)-4-[2,4-二氟-5-(5-嘧啶基)苯基]-5,6-二氢-4-甲基-4H-1,3-噻嗪-2-胺
A BACE1 inhibitor
GC15706 Aspirin (Acetylsalicylic acid)
阿司匹林; Acetylsalicylic Acid; ASA
A non-selective, irreversible COX inhibitor
GC12942 DAPT (GSI-IX)
gamma-Secretase Inhibitor IX, DAPT, GSI-IX
DAPT (GSI-IX) 是一种具有口服活性的 γ-分泌酶抑制剂，对人原代神经元培养物中产生的总淀粉样蛋白-β (Aβ) 和 Aβ42 的 IC50 分别为 115 nM 和 200 nM。
GN10122 Linalool
芳樟醇
A monoterpene alcohol with diverse biological activities
GN10022 luteolin-6-C-glucoside
异荭草素; Homoorientin
A flavonoid with diverse biological activities
GN10145 Rhodionin
草质素苷
Rhodionin 是从 Rhodiola crenulata 的根中分离出来的，是一种特异性的非竞争性细胞色素 P450 2D6 抑制剂，IC50 为 0.761 μM，Ki 为 0.769 μM。
GN10313 Schisantherin B
五味子酯乙,Gomisin-B; Wuweizi ester-B; Schisantherin-B
A lignan
GN10685 Anemarsaponin B
知母皂苷 B
Anemarsaponin B 是一种甾体皂苷。
GN10542 Scopolamine butylbromide
丁溴东莨菪碱,Hyoscine butylbromide; (-)-Scopolamine butylbromide; Butylscopolamine bromide
An antispasmodic agent
GN10254 Ginsenoside Rc
人参皂苷 Rc; Panaxoside Rc
A saponin with diverse biological activities
GN10283 Rosiridin
络塞定
Rosiridin 抑制 MAO A 和 MAO B，对抑郁症和老年痴呆症具有潜在的有益作用。
GN10513 Tetrahydroberberine,THB
四氢小檗碱; Canadine
An isoquinoline alkaloid with diverse biological activities
GN10074 Xanthotoxol
花椒毒醇,8-Hydroxypsoralen
A coumarin with diverse biological activities
GN10004 EsculentosideA
商陆皂苷甲
EsculentosideA (EsA)，一种从商陆根中分离得到的三萜皂苷。
GN10716 Epiberberine
表小檗碱
An alkaloid with diverse biological activities
GN10155 (+)- Corydaline
紫堇碱; (+)-Corydaline; Corydalin
An alkaloid with diverse biological activities
GN10311 N－Methylcytisine
N-甲基野靛碱,Caulophylline
An alkaloid with diverse biological activities
GN10080 Byakangelicol
白当归脑
A furanocoumarin with diverse biological activities
GN10645 Jaceosidin
棕矢车菊素
A natural methylated trihydroxyflavone
GN10186 Isocorynoxeine
异去氢钩藤碱; 7-Isocorynoxeine
An alkaloid with diverse biological activities
GC12096 Semagacestat (LY450139)
司马西特,LY-450139, LY 450139,Semagacestat
A pan γ-secretase inhibitor
GN10654 (+)-Corynoline
紫蓳灵
An isoquinoline alkaloid with diverse biological activities
GN10616 Timosaponin A3
知母皂苷A-III,Xilingsaponin A; Zhi-mu saponin
A natural steroid saponin
GN10251 Ginkgolide A
银杏内酯A; BN-52020
A terpenoid lactone with diverse biological activities
GN10502 Saikosaponin C
柴胡皂苷 C
A saikosaponin with anti-inflammatory and analgesic activities
GN10430 D-(-)-Salicin
水杨苷; D-(?)-Salicin; Salicoside
A non-selective COX inhibitor
GN10437 Imperatorin
欧前胡素; Ammidin
A furanocoumarin with diverse biological activities
GN10429 Neochlorogenic acid
新绿原酸; trans-5-O-Caffeoylquinic acid
A phenolic compound with diverse biological activities
GN10498 Paeonol
丹皮酚
A phenol with diverse biological activities
GN10388 Gallic acid
没食子酸; 3,4,5-Trihydroxybenzoic acid
A phenol with diverse biological activities
GN10333 Osthole
蛇床子素; Osthol; NSC 31868
A coumarin with diverse biological activities
GN10648 Rosmarinic acid
迷迭香酸; Labiatenic acid
Rosmarinic acid是一种广泛存在于植物中的酚酯化合物。Rosmarinic acid具有抗病毒、抗菌、抗炎、神经保护、抗癌、抗脂质过氧化、细胞凋亡和抗氧化活性。
GN10352 Isoimperatorin
异欧前胡素
A furanocoumarin that inhibits CYP1A
GN10578 Polygalacic acid
毛果一枝黄花皂苷元G
A triterpenoid saponin with antioxidant and neuroprotective activities
GN10126 Cytisine
金雀花碱; Cytisine; Sophorine; Baptitoxine
An alkaloid and a partial agonist of nAChRs
GN10605 (+)-Catechin hydrate
(+)-水合儿茶素
A polyphenolic flavonoid with diverse biological activities
GN10220 Ginsenoside Rb3
人参皂苷 Rb3; Gypenoside IV
A steroid glycoside with diverse biological activities