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(+)-Corynoline

目录号 GN10654

Extracted from corydalis sheareri S. Moore;Store the product in sealed,cool and dry condition

规格 价格 库存 购买数量
20mg
¥1,620.00
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Sample solution is provided at 25 µL, 10mM.

质量管理

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产品描述

Corynoline, isolated from Corydalis incise (Papaveraceae), is a reversible and noncompetitive acetylcholinesterase (AChE) inhibitor with an IC50 of 30.6 μM[1]. Corynoline exhibits anti-inflammatory activity by activating Nrf2[2].

References:
[1]. Kim DK. Inhibitory effect of corynoline isolated from the aerial parts of Corydalis incisa on the acetylcholinesterase. Arch Pharm Res. 2002 Dec;25(6):817-9.
[2]. Liu B, et al. Corynoline Exhibits Anti-inflammatory Effects in Lipopolysaccharide (LPS)-Stimulated Human Umbilical Vein Endothelial Cells through Activating Nrf2. Inflammation. 2018 Oct;41(5):1640-1647.

Chemical Properties

Cas No. 18797-79-0 SDF
化学名 5b,13-dimethyl-5b,6,7,12b,13,14-hexahydro-[1,3]dioxolo[4',5':4,5]benzo[1,2-c][1,3]dioxolo[4,5-i]phenanthridin-6-ol
Canonical SMILES [H]C1(C2=C([H])C3=C4OC([H])([H])O3)N(C([H])([H])[H])C([H])([H])C5=C(C([H])=C([H])C6=C5OC([H])([H])O6)C1(C([H])([H])[H])C(C([H])([H])C2=C4[H])([H])O[H]
分子式 C21H21NO5 分子量 367.14
溶解度 Chloroform: 10 mg/ml,DMF: slightly soluble,Ethanol: slightly soluble 储存条件
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

动物体内配方计算器 (澄清溶液)

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