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Home >> Signaling Pathways >> Neuroscience

Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for  Neuroscience

  1. Cat.No. 产品名称 Information
  2. GC16891 Quetiapine Fumarate

    富马酸喹硫平

     An antagonist of diverse neurological receptors
  3. GC15223 Tropisetron Hydrochloride

    盐酸托烷司琼

     A 5-HT3 receptor antagonist
  4. GC16716 Sulindac

    舒林酸; MK-231

     A non-selective COX inhibitor
  5. GC11651 Ondansetron hydrochloride dihydrate

    盐酸昂丹司琼二水物; GR 38032 hydrochloride dihydrate; SN 307 hydrochloride dihydrate

     An Analytical Reference Material
  6. GC13792 Rufinamide

    卢非酰胺; CGP 33101; E 2080; RUF 331

     An anticonvulsant
  7. GC16087 Fesoterodine Fumarate

    富马酸非索罗定

     A muscarinic acetylcholine receptor antagonist
  8. GC14512 Fenspiride HCl

    盐酸芬司必利

     A histamine H1 receptor antagonist
  9. GC11219 (R)-(+)-Tolterodine

    托特罗定; (R)-(+)-Tolterodine; (+)-Tolterodine; (R)-Tolterodine; PNU-200583

     (R)-(+)-Tolterodine(PNU-200583) 是一种有效的毒蕈碱受体拮抗剂，在体内对膀胱的选择性优于唾液腺。
  10. GC17917 Palonosetron HCl

    盐酸帕洛诺司琼

     A 5-HT3 receptor antagonist
  11. GC14250 Bepotastine Besilate

    苯磺酸贝托司汀

     A histamine H1 receptor antagonist
  12. GC15772 Darifenacin HBr

    氢溴酸达非那新; UK-88525 hydrobromide

     A muscarinic M3 receptor antagonist
  13. GC17053 Eletriptan HBr

    依来曲普坦氢溴酸盐; Eletriptan HBr; UK-116044 hydrobromide

     An agonist of 5-HT1B and 5-HT1D receptors
  14. GC17182 Solifenacin succinate

    索非那新琥珀酸盐; YM905

     A muscarinic M1, M2, and M3 receptor antagonist
  15. GC17954 Tolterodine tartrate

    酒石酸托特罗定,Kabi-2234; PNU-200583E

     A muscarinic acetylcholine receptor antagonist
  16. GC13114 (S)-(+)-Ibuprofen

    (S)-(+)-布洛芬; (S)-Ibuprofen

     An active enantiomer of ibuprofen
  17. GC16662 Etodolac

    依托度酸; AY-24236

     An NSAID
  18. GC11182 LY404039

    (1R,4S,5S,6S)-4-氨基-2-硫杂双环[3.1.0]己烷-4,6-二甲酸2,2-二氧化物

     An agonist of mGluR2 and mGluR3
  19. GC10443 Meclofenoxate hydrochloride

    盐酸甲氯酚酯

     A nootropic agent
  20. GC16899 Coluracetam

    考拉西坦; MKC-231

     An Analytical Reference Standard
  21. GC12123 sn-Glycero-3-phosphocholine

    甘磷酸胆碱; Choline Alfoscerate; Alpha-GPC; L-α-GPC

     A nootropic phospholipid
  22. GC16077 Deracoxib

    地拉考昔; SC 046; SC 46; SC 59046

     An NSAID and selective COX-2 inhibitor
  23. GC17051 Parecoxib Sodium

    帕瑞昔布钠; SC 69124A

     A prodrug form of valdecoxib
  24. GC15029 Glycopyrrolate

    格隆溴铵; Glycopyrronium bromide; Glycopyrrolate bromide

     A muscarinic acetylcholine receptor antagonist
  25. GC12061 Tripelennamine HCl

    盐酸吡苄明；去敏灵；扑敏宁；盐酸吡甲胺；盐酸吡苯胺

     Tripelennamine HCl 是一种乙二胺衍生物，是一种有效的组胺 H1 受体拮抗剂。
  26. GC10799 Iloperidone hydrochloride

    盐酸伊潘立酮; HP 873 hydrochloride

     An atypical antipsychotic
  27. GC13081 Loxapine

    洛沙平

     洛沙平是一种口服活性多巴胺抑制剂、5-HT 受体拮抗剂，也是一种二苯并沙西平抗精神病药物。
  28. GC10516 Rofecoxib

    罗非考昔; MK 966

     A COX-2 inhibitor
  29. GC14111 (R)-baclofen

    (R)-巴氯芬; Arbaclofen; STX209

     (R)-巴氯芬 (Arbaclofen) 是一种选择性 GABAB 受体激动剂。
  30. GC11009 Cetirizine DiHCl

    盐酸西替利嗪; P071

     A selective histamine H1 receptor antagonist
  31. GC17981 Agomelatine

    阿戈美拉汀; S-20098

     Agomelatine是一种褪黑素（MT）受体激动剂，对MT1和MT2的Ki值分别为0.1 nM和0.12 nM。Agomelatine也是一种5-羟色胺（5-HT）受体拮抗剂，对5-HT2C 和5-HT2B 的Ki值分别为631 nM和660 nM。
  32. GC11470 Flupirtine maleate

    氟吡啶马来酸

     An activator of Kv7 channels
  33. GC14039 MDL-29951

    An NMDA receptor antagonist and GPR17 agonist
  34. GC11186 Brexpiprazole

    依匹哌唑; OPC-34712

     A serotonin and dopamine receptor modulator
  35. GC14020 Valdecoxib

    伐地考昔; SC 65872

     A COX-2 inhibitor
  36. GC10450 PRX-08066 A 5-HT2B receptor antagonist
  37. GC14207 GW791343 HCl GW791343 HCl 是一种有效的人 P2X7 受体负变构调节剂（表现出物种特异性活性），对人 P2X7 受体产生非竞争性拮抗作用，pIC50 为 6.9-7.2。
  38. GC12501 KN-93 hydrochloride A selective inhibitor of Ca2+/calmodulin-dependent kinase type II
  39. GC10769 SB269970 HCl

    SB-269970A

     SB269970 HCl是一种强效且选择性的5-HT7受体拮抗剂，具有高亲和力 (pKi = 8.9)。
  40. GC15847 Ciproxifan maleate

    环丙基[4-[3-(1H-咪唑-4-基)丙氧基]苯基]甲酮马来酸盐,FUB 359 maleate

     A histamine H3 receptor antagonist
  41. GC10974 AWD 131-138

    伊匹妥英,AWD 131-138

     A partial agonist of the GABAA receptor
  42. GC15121 Lasmiditan

    拉米地坦

     An Analytical Reference Standard
  43. GC16059 Tarafenacin D-tartrate

    SVT-40776 D-tartrate

     Tarafenacin D-tartrate (SVT-40776 D-tartrate) 是一种高度选择性的 M3 毒蕈碱受体拮抗剂 (Ki= 0.19 nM)，选择性是 M2 受体的约 200 倍。
  44. GC13618 Tarafenacin

    他利那新,SVT-40776

     Tarafenacin(SVT-40776) 是一种高度选择性的 M3 毒蕈碱受体拮抗剂 (Ki= 0.19 nM)，选择性比 M2 受体高约 200 倍。
  45. GC12924 Ciproxifan

    FUB-359

     A histamine H3 receptor antagonist
  46. GC10945 Tandospirone

    坦度螺酮; SM-3997

     Tandospirone (SM-3997) 是一种有效的选择性 5-HT1A 受体部分激动剂，Ki 为 27 nM。
  47. GC10117 Aripiprazole

    阿立哌唑; OPC-14597

     An atypical antipsychotic
  48. GC12610 Amisulpride

    氨磺必利; DAN 2163

     A dopamine D2 and D3 and 5-HT2B, 5-HT7, and 5-HT7A receptor antagonist
  49. GC12495 Olanzapine

    奥氮平; LY170053

     An atypical antipsychotic
  50. GC17760 Clozapine

    氯氮平; HF 1854

     An atypical antipsychotic
  51. GC11506 Haloperidol hydrochloride

    氟哌啶醇盐酸盐

     A typical antipsychotic and dopamine D2-like receptor antagonist

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