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Home >> Signaling Pathways >> Neuroscience

Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for  Neuroscience

  1. Cat.No. 产品名称 Information
  2. GC14008 Anpirtoline hydrochloride 5-HT1B receptor agonist
  3. GC11945 BTCP maleate dopamine reuptake inhibitor
  4. GC15856 3'-Fluorobenzylspiperone maleate

    ligand for the D2 receptor
  5. GC13156 (+)-AJ 76 hydrochloride (+)-AJ 76 hydrochloride是一种对突触前受体具有优先作用的多巴胺受体（dopamine receptors, DRs）拮抗剂（hD3、hD4、hD2S、hD2L和rD2受体的pKi值分别为6.95、6.67、6.37、6.21和6.07）。
  6. GC12472 Amthamine dihydrobromide A histamine H2 receptor agonist
  7. GC17429 HTMT dimaleate

    HTMT马来酸氢盐

     A histamine H1 receptor agonist
  8. GC13496 Thioperamide

    硫丙咪胺,MR-12842

     A histamine H3 receptor antagonist
  9. GC12276 CGS 12066B dimaleate A 5-HT1B receptor agonist
  10. GC11269 Salsolinol-1-carboxylic acid Salsolinol-1-carboxy acid 是中枢神经系统 (CNS) 中的一种内源性生物碱。
  11. GC10357 Metergoline

    甲麦角林

     A serotonin receptor antagonist
  12. GC16487 Nα-Methylhistamine dihydrochloride

    histamine H3 receptor agonist
  13. GC10704 (S)-(+)-α-Methylhistamine dihydrobromide H3 histamine receptor agonist
  14. GC15311 BP 554 maleate Selective 5-HT1A agonist
  15. GC15235 NAN-190 hydrobromide A 5-HT1A receptor mixed antagonist and partial agonist
  16. GC13129 W-84 dibromide

    HDMPPA

     W-84 (dibromide) 是一种有效的 M2-胆碱受体变构调节剂，可延缓 [3H]N-甲基东莨菪碱的解离。
  17. GC14966 8-Hydroxy-DPAT hydrobromide

    7-(二丙基氨基)-5,6,7,8-四氢-1-萘酚氢溴酸盐,8-Hydroxy-DPAT hydrobromide

     A 5-HT1A receptor agonist
  18. GC16049 AMI-193

    螺哌丙苯,AMI-193

     AMI-193 (AMI-193) 是一种有效的、选择性的 5-HT2 和多巴胺 D2 受体拮抗剂，Kis 分别为 2 nM 和 3 nM。
  19. GC12456 GBR 12783 dihydrochloride GBR 12783 dihydrochloride 是一种特异性、有效和选择性的多巴胺摄取抑制剂，抑制大鼠和小鼠纹状体突触体对 [3H] 多巴胺的摄取，IC50 分别为 1.8 nM 和 1.2 nM。
  20. GC10525 Nitrocaramiphen hydrochloride M1 muscarinic antagonist
  21. GC16135 Cinanserin hydrochloride

    SQ 10643

     A 5-HT receptor antagonist
  22. GC10009 Benzoquinonium dibromide Benzoquinonium dibromide 是一种烟碱型乙酰胆碱受体 (nAChRs) 拮抗剂，IC50 为 0.46 μM。
  23. GC12179 GBR 13069 dihydrochloride dopamine uptake inhibitor
  24. GC10985 MDL 72832 hydrochloride ligand for 5-HT1A receptor, potent and selective
  25. GC14019 MDL 73005EF hydrochloride 5-HT1A receptor antagonist
  26. GC13222 N-Acetylglycyl-D-glutamic acid Excitatory peptide that induces seizures
  27. GC16974 Ambenonium dichloride

    安贝氯铵,WIN 8077 chloride

     Ambenonium (WIN 8077) chloride 是一种具有高亲和力的具有口服活性且可逆的乙酰胆碱酯酶 (AChE) 抑制剂。
  28. GC16504 Arecaidine propargyl ester tosylate muscarinic receptor agonist
  29. GC11415 Arecaidine but-2-ynyl ester tosylate mAChR M2 激动剂
  30. GC14156 NBQX

    二羟基喹酮,FG9202

     NBQX是一种高度选择性和竞争性的AMPA受体拮抗剂。
  31. GC15383 4-Acetyl-1,1-dimethylpiperazinium iodide nicotinic agonist
  32. GC18009 1-Acetyl-4-methylpiperazine hydrochloride nAChR agonist
  33. GC15136 L-AP6

    DL-2-氨基-6-膦酰己酸

     selective agonist for 'quis'-sensitized site
  34. GC16349 (S)-MCPG

    (+)-MCPG

     An mGluR antagonist
  35. GC12279 (RS)-MCPG

    alpha-MCPG

     (RS)-MCPG (alpha-MCPG) 是一种竞争性和选择性的 I 组/II 组代谢型谷氨酸受体 (mGluR) 拮抗剂。
  36. GC11536 (S)-3-Carboxy-4-hydroxyphenylglycine group I metabotropic glutamate receptor antagonist and group II mGlu agonist
  37. GC14124 (R)-3-Carboxy-4-hydroxyphenylglycine NMDA and AMPA/kainate receptor antagonist
  38. GC16234 (S)-3-Hydroxyphenylglycine

    (S)-3-羟基苯甘氨酸

     group I metabotropic glutamate receptors agonist
  39. GC12985 (RS)-3-Hydroxyphenylglycine

    3-羟基苯甘氨酸

     PI-linked metabotropic glutamate receptors agonist
  40. GC14176 (S)-4-Carboxyphenylglycine group I metabotropic glutamate receptor antagonist
  41. GC13773 (RS)-4-Carboxyphenylglycine broad spectrum EAA ligand
  42. GC12012 (S)-4-Carboxy-3-hydroxyphenylglycine group I mGlu1a/1a receptor antagonist and mGluR2 agonist
  43. GC13288 (RS)-4-Carboxy-3-hydroxyphenylglycine

    (RS)-4-羧基-3-羟基苯甘氨酸

     broad spectrum EAA agonist/antagonist
  44. GC11889 (S)-(-)-5-Fluorowillardiine

    5-氟代尿嘧啶丙氨酸; (5S)-Fluorowillardiine; (S)-5-Fluorowillardiine

     (S)-(-)-5-Fluorowillardiine 是一种有效且特异性的 AMPAR 激动剂。
  45. GC16207 (1S,3R)-ACPD

    反-(1S,3R)-1-氨基-1,3-环戊烷二羧酸

     group I and II mGlu receptor agonist
  46. GC14752 2,4-Dihydroxyphenylacetyl-L-asparagine glutamate receptors blocker
  47. GC10781 7-Chlorokynurenic acid

    7-氯犬尿酸,7-CKA

     A glycine-site selective NMDA receptor antagonist
  48. GC11799 CNQX

    6-氰基-7-硝基喹喔啉-2,3-二酮,FG9065

     CNQX是一种有效的竞争性AMPA /海藻酸酯受体(AMPA/kainate receptor)拮抗剂,IC50 分别为0.3µM和1.5µM。
  49. GC12394 (±)-trans-ACPD

    Trans-(±)-ACP

     An mGluR agonist
  50. GC10026 S-Sulfo-L-cysteine sodium salt EAA receptor agonist
  51. GC12063 D-AP4

    D(-)-2-氨基-4-磷酸基丁酸,D-APB; D-2-Amino-4-phosphonobutyric acid

     D-AP4 (D-APB; D-2-Amino-4-phosphonobutyric acid) 是一种谷氨酸的膦酰基类似物，是一种 NMDA 广谱兴奋性氨基酸受体拮抗剂。

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