Neuroscience(神经科学)

Neuroscience
Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more
Products for Neuroscience
- 5-HT Receptor(420)
- AChR(53)
- AChE(100)
- Alzheimer(107)
- Amyloid β(118)
- BACE(4)
- CGRP (33)
- COX(294)
- DAPK(7)
- Dopamine Receptor(290)
- GABA Receptor(155)
- Gap Junction(16)
- GluR(116)
- Histamine(2)
- Histamine Receptor(236)
- mPEGS-1(4)
- Muscarinic Receptor(41)
- Neuroscience Peptides(38)
- Nicotinic Receptor(62)
- P2 Receptor(2)
- P2X7 receptor(3)
- SSRIs(5)
- Substance P/NK1 Receptor(20)
- NMDA(2)
- Beta-secretase(25)
- CaMK(32)
- Dopamine Transporter(20)
- Monoamine Oxidase(91)
- Serotonin Transporter(57)
- nAChR(100)
- iGluR(155)
- Neurokinin Receptor(75)
- MCHR1 (GPR24)(16)
- mAChR(183)
- GPR139(4)
- Cholecystokinin Receptor(25)
- Behavioral Neuroscience(353)
- DREADD(1)
- Huntington(14)
- Neuroendocrinology(64)
- Neuroprotection(117)
- Ophthalmology(158)
- Pain Research(229)
- Parkinson(73)
- Prion(7)
- Seizure Disorders(94)
- Cholinesterases(13)
- Tau Protein(4)
- Neurodegenerative Disorders(5)
- Cholinesterase (ChE)(3)
- Amyloid-β(9)
- γ-secretase(1)
- Ischemia(3)
- Cat.No. 产品名称 Information
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GC11902
PNU 96415E
PNU 96415E 是一种选择性 D4/5-HT2A 拮抗剂。
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GC13109
Fananserin
法南色林,RP 62203
Fananserin (RP 62203) 是一种口服有效的选择性 5-hydroxytryptamine2 (5-HT2) 受体拮抗剂,对大鼠 5-HT2A 受体的 Ki 值为 0.37 nM。 -
GC18068
NGB 2904
A selective D3 antagonist
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GC14619
Milameline hydrochloride
Muscarinic receptor agonist
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GC17238
OSU 6162 hydrochloride
Dopamine stabilizer
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GC11853
Tenidap
替尼达普,CP-66248
A COX-1 selective NSAID -
GC18082
Zamifenacin fumarate
扎非那星富马酸盐; UK-76654 fumarate
A muscarinic M3 receptor antagonist -
GC14842
GYKI 53655 hydrochloride
LY300168 hydrochloride
GYKI 53655 (LY300168) hydrochloride 是一种 α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) 拮抗剂。 -
GC11495
Lofepramine
洛非帕明,Lopramine
A tricyclic antidepressant -
GC15132
TC 1698 dihydrochloride
nicotinic α7 receptor agonist
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GC17564
VUF 8430 dihydrobromide
A histamine H4 receptor agonist
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GC16018
VUF 5681 dihydrobromide
histamine H3 receptor silent antagonist
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GC15957
Proxyfan oxalate
组胺H3受体配体
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GC14861
LY 379268
A selective group II mGlu2/3 receptor agonist
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GC15566
YM 298198 hydrochloride
A non-competitive antagonist of mGluR1
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GC13120
Desmethyl-YM 298198
mGlu1-selective antagonist
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GC14429
JNJ 10191584 maleate
histamine H4 receptor silent antagonist
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GC11406
TMPH hydrochloride
neuronal nicotinic ACh receptors (nAChRs) antagonist
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GC16180
GT 2016
A histamine H3 receptor antagonist
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GC10425
Ro 90-7501
An antiviral useful in Alzheimer’s research
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GC17492
LY 456236 hydrochloride
mGlu1 receptor antagonist
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GC11766
Fenobam
非诺班
A noncompetitive antagonist and inverse agonist of mGluR5 -
GC11287
AMN 082 dihydrochloride
An allosteric mGluR7 agonist
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GC13118
Dihydro-β-erythroidine hydrobromide
DHβE hydrobromide
Dihydro-β-erythroidine (DHβE) hydrobromide 是一种有效的、具有口服活性的竞争性神经元 nAChR 拮抗剂。 -
GC16300
ZK 200775
ZK200775; MPQX
ZK 200775 (ZK200775) 是一种高度选择性的 AMPA/红藻氨酸拮抗剂,对 NMDA 几乎没有活性; Ki 值分别为 3.2 nM、100 nM 和 8.5 μ;M 分别针对 quisqualate、红藻氨酸和 NMDA。 -
GC12737
4-Methylhistamine dihydrochloride
2-(4-甲基-1H-咪唑基-5-基)乙胺二盐酸盐
A histamine H4 receptor agonist -
GC17217
JNJ 16259685
An antagonist of mGluR1a
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GC12428
Ro 10-5824 dihydrochloride
Ro 10-5824 dihydrochloride 是一种选择性多巴胺 D4 受体部分激动剂,Ki 为 5.2 nM。
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GC14260
Immethridine dihydrobromide
A potent histamine H3 receptor agonist
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GC18139
Devazepide
地伐西匹; L-364,718; MK-329
Devazepide (L-364,718) 是一种有效、竞争性、选择性和口服活性的胆囊收缩素 (CCK) 受体非肽拮抗剂,对大鼠胰腺、牛胆囊和豚鼠脑 CCK 受体的 IC50 分别为 81 pM、45 pM 和 245 nM . -
GC12952
PNU 282987
PNU 282987是一种选择性α7烟碱乙酰胆碱受体(α7nAChR)激动剂,与抗炎途径相关,也是5-HT3受体的拮抗剂,PNU 282987对α7nAChR的EC50为154nM (Ki α7nAChR=27nM,大鼠脑匀浆),对5-HT3受体的IC50为4541nM (Ki 5-HT3R=1662nM, GR-65630)。
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GC16992
SCH 39166 hydrobromide
A dopamine D1 receptor antagonist
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GC13340
AQ-RA 741
M2 antagonist,selective and high affinity
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GC17079
ACDPP hydrochloride
mGlu5 receptor antagonist
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GC11795
ABT 724 trihydrochloride
A dopamine D4 receptor agonist
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GC11223
3-MATIDA
mGlu1 receptor antagonist
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GC15343
Eliprodil
依利罗地,SL-820715
An NMDA receptor antagonist -
GC14583
R 59-022
DKGI-I; Diacylglycerol kinase inhibitor I
R 59-022是一种二酰甘油激酶抑制剂(IC50 = 2.8µM)。 -
GC14826
Carmoxirole hydrochloride
EMD 45609 hydrochloride
Carmoxirole hydrochloride (EMD 45609 hydrochloride) 是一种选择性的、外周作用的多巴胺 D2 受体激动剂,在体内表现出抗高血压活性。 -
GC14258
SR 27897
SR 27897
A nonpeptide CCK1 antagonist -
GC16735
(±)-McN 5652
5-HT uptake inhibitor
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GC18102
Paroxetine maleate
马来酸帕罗西汀
5-HT uptake inhibitor -
GC10633
DAU 5884 hydrochloride
muscarinic M3 receptor antagonist
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GC11503
SKF 83822 hydrobromide
SKF 83822 hydrobromide 是一种有效的多巴胺 D1 受体激动剂。
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GC11146
SKF 83959 hydrobromide
A dopamine D1 and D5 receptor partial agonist
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GC12085
ROS 234 dioxalate
ROS 234 dioxalate 是一种有效的 H3 拮抗剂,对豚鼠回肠 H3 受体的 pKB 为 9.46,对大鼠大脑皮层 H3 受体的 pKi 为 8.90,在体外的 ED50 为 19.12 mg/kg (ip)大鼠大脑皮层。
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GC16780
Ro 15-4513
Ro 15-4513,咪唑并苯二氮卓衍生物,是苯二氮卓受体 (BZR) 的部分反向激动剂。
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GC17525
AS 19
A 5-HT7 receptor agonist
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GC13883
Ritanserin
利坦丝林,R 55667
A potent 5-HT2A receptor antagonist -
GC13126
DMeOB
Negative allosteric modulator of mGlu5