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Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for  Neuroscience

  1. Cat.No. 产品名称 Information
  2. GC12804 KN-93 Phosphate A CaMKII inhibitor
  3. GC10603 (-)-epicatechin gallate

    表儿茶素没食子酸酯; Epicatechin gallate; ECG; (-)-Epicatechin 3-O-gallate

    A natural polyphenol with diverse protective actions
  4. GC13474 Garcinol

    山竹子素

    Garcinol是组蛋白乙酰转移酶p300和PCAF的非特异性抑制剂,IC50分别为7μM和5μM。

  5. GC17681 Gap19 Gap19 (KQIEIKKFK) 阻断 HC 但不阻断 GJC,并且特定于 Cx43。
  6. GC10321 Decloxizine

    去氯羟嗪; UCB-1402; NSC289116

    Decloxizine(UCB-1402; NSC289116) 是一种组胺 1 受体拮抗剂。
  7. GC14612 JNJ-31020028 An antagonist of NPY receptor Y2
  8. GC12397 Firocoxib

    非罗考昔; ML 1785713

    An inhibitor of COX-2
  9. GC16562 PEAQX

    NVP-AAM077

    PEAQX(NVP-AAM 077) 是一种有效的、具有口服活性的 NMDA 拮抗剂,对人 NMDA 受体的 1A/2A(IC50=270 nM) 比 1A/2B(29,600 nM) 高 15 倍。
  10. GC13445 LY2119620

    3-氨基-5-氯-N-环丙基-4-甲基-6-[2-(4-甲基-1-哌嗪基)-2-氧代乙氧基]-噻吩并[2,3-B]吡啶-2-甲酰胺

    A positive allosteric modulator of M2 and M4 mAChRs
  11. GC17627 Nitenpyram

    烯啶虫胺

    An insecticide
  12. GC10814 Promethazine HCl

    盐酸异丙嗪

    A histamine H1 receptor antagonist
  13. GC10300 Diphenidol HCl

    盐酸地芬尼多; Difenidol hydrochloride

    A muscarinic acetylcholine receptor antagonist
  14. GC11309 ARN2966

    2-PMAP

    An inhibitor of APP production and Aβ secretion
  15. GC11844 Pimavanserin

    匹莫范色林; ACP-103

    A 5-HT2A inverse agonist
  16. GC11963 Oxiracetam

    奥拉西坦,ISF2522

    An Analytical Reference Standard
  17. GC17047 Threo-methylphenidate hydrochloride

    盐酸哌甲酯

    盐酸苏哌甲酯(Threo-methylphenidate hydrochloride)是一种儿茶酚胺再摄取抑制剂,抑制多巴胺转运蛋白(DAT)和去甲肾上腺素转运蛋白(NET)。
  18. GC10913 GTS 21 dihydrochloride

    (3E)-3-[(2,4-二甲氧基苯基)亚甲基]-3,4,5,6-四氢-2,3'-联吡啶二盐酸盐,DMXB-A; DMBX-anabaseine

    An agonist of α7-containing nAChRs
  19. GC16315 D-AP5

    (R)-(-)-2-氨基-5-膦酰戊酸,D-2-Amino-5-Phosphonovaleric acid; D-APV

    D-AP5是一种选择性N-甲基-D-天门冬胺酸(NMDA)受体拮抗剂,Kd 值为1.4μM。
  20. GC16247 DCG IV DCG IV 是 II 组 mGluRs 的有效激动剂,对 mGlu2R 和 mGlu3R 的 EC50 分别为 0.35 和 0.09 μM。
  21. GC17950 MMPIP hydrochloride A reversible allosteric antagonist of mGluR7
  22. GC12703 Philanthotoxin 74

    PhTx 74 dihydrochloride

    An AMPA receptor antagonist
  23. GC17932 L-AP4

    L(+)-2-氨基-4-膦酰基丁酸,L-APB

    A selective Group III metabotropic glutamate receptor agonist
  24. GC10988 J 147 J 147 是一种非常有效的口服活性神经保护剂,用于增强认知能力。
  25. GC12800 PAOPA dopamine D2 receptor modulator
  26. GC17095 ML 337 ML 337 是一种选择性和脑渗透性的 mGlu3 负变构调节剂,IC50 为 593 nM。
  27. GC14869 ML 289

    VU0463597

    A negative allosteric modulator of mGlu3
  28. GC10894 Methoxy-X04 Methoxy-X04是一种具有荧光性的刚果红和柯胺G的衍生物,不含酸性基团,分子量更小且亲脂性更强。
  29. GC17385 KML 29

    An inhibitor of MAGL

  30. GC16776 QNZ 46 An antagonist of NR2C- and NR2D-subunit containing NMDA receptors
  31. GC17585 VUF 10460 A histamine H4 receptor agonist
  32. GC12959 SIB 1553A hydrochloride A β4 subunit-selective nAChR agonist
  33. GC14610 A 412997 dihydrochloride Selective D4 agonist
  34. GC14508 PTAC oxalate muscarinic receptor ligand
  35. GC12937 STF 083010

    IRE1 Inhibitor I

    An inhibitor of IRE1 endonuclease activity
  36. GC12739 A 484954 An eEF-2K inhibitor
  37. GC15333 A 844606 α7 nAChR partial agonist
  38. GC16242 SEN 12333

    WAY-317538

    An agonist of α7 nAChRs
  39. GC10045 MFZ 10-7 MFZ 10-7 是一种有效的 mGluR5 拮抗剂。
  40. GC13052 SR 16584 Selective antagonist of α3β4 nicotinic acetylcholine receptors
  41. GC12460 ADX 10059 hydrochloride Negative allosteric modulator at mGlu5
  42. GC13715 MK 0343

    MRK-409

    MK0343 (MRK-409) 是一种口服生物可利用的 GABAA 受体亚型选择性部分激动剂。
  43. GC17821 VU 0365114 A positive allosteric modulator of muscarinic M5 receptors
  44. GC11986 VU 0360223

    CAY10651

    A negative allosteric modulator of the mGlu5 receptor
  45. GC10238 MNI 137 MNI 137 是一种有效的、选择性的负变构调节剂,适用于 II 组 mGluR。
  46. GC16643 VU 0285683 negative allosteric modulator of mGlu5 receptors
  47. GC13290 CMPDA A positive allosteric modulator of GluA2
  48. GC11750 TC-N 22A TC-N 22A 是一种有效的、选择性的、具有口服活性和脑渗透性的 mGlu4 PAM,在表达人 mGlu4 的 BHK 细胞中的 EC50 为 9 nM。
  49. GC12485 Ro 67-7476 A positive allosteric modulator of mGluR1
  50. GC10323 VU 0360172 hydrochloride A positive allosteric modulator of mGluR5
  51. GC14743 WY 45233 succinate

    去甲文拉法辛(O-去甲文拉法辛)琥珀酸,O-Desmethylvenlafaxine succinate; Wy-45233 succinate

    serotonin and noradrenalin reuptake inhibitor

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