Neuroscience(神经科学)

Neuroscience
Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more
Products for Neuroscience
- 5-HT Receptor(420)
- AChR(53)
- AChE(100)
- Alzheimer(107)
- Amyloid β(118)
- BACE(4)
- CGRP (33)
- COX(294)
- DAPK(7)
- Dopamine Receptor(290)
- GABA Receptor(155)
- Gap Junction(16)
- GluR(116)
- Histamine(2)
- Histamine Receptor(236)
- mPEGS-1(4)
- Muscarinic Receptor(41)
- Neuroscience Peptides(38)
- Nicotinic Receptor(62)
- P2 Receptor(2)
- P2X7 receptor(3)
- SSRIs(5)
- Substance P/NK1 Receptor(20)
- NMDA(2)
- Beta-secretase(25)
- CaMK(32)
- Dopamine Transporter(20)
- Monoamine Oxidase(91)
- Serotonin Transporter(57)
- nAChR(100)
- iGluR(155)
- Neurokinin Receptor(75)
- MCHR1 (GPR24)(16)
- mAChR(183)
- GPR139(4)
- Cholecystokinin Receptor(25)
- Behavioral Neuroscience(353)
- DREADD(1)
- Huntington(14)
- Neuroendocrinology(64)
- Neuroprotection(117)
- Ophthalmology(158)
- Pain Research(229)
- Parkinson(73)
- Prion(7)
- Seizure Disorders(94)
- Cholinesterases(13)
- Tau Protein(4)
- Neurodegenerative Disorders(5)
- Cholinesterase (ChE)(3)
- Amyloid-β(9)
- γ-secretase(1)
- Ischemia(3)
- Cat.No. 产品名称 Information
-
GC12804
KN-93 Phosphate
A CaMKII inhibitor
-
GC10603
(-)-epicatechin gallate
表儿茶素没食子酸酯; Epicatechin gallate; ECG; (-)-Epicatechin 3-O-gallate
A natural polyphenol with diverse protective actions -
GC13474
Garcinol
山竹子素
Garcinol是组蛋白乙酰转移酶p300和PCAF的非特异性抑制剂,IC50分别为7μM和5μM。
-
GC17681
Gap19
Gap19 (KQIEIKKFK) 阻断 HC 但不阻断 GJC,并且特定于 Cx43。
-
GC10321
Decloxizine
去氯羟嗪; UCB-1402; NSC289116
Decloxizine(UCB-1402; NSC289116) 是一种组胺 1 受体拮抗剂。 -
GC14612
JNJ-31020028
An antagonist of NPY receptor Y2
-
GC12397
Firocoxib
非罗考昔; ML 1785713
An inhibitor of COX-2 -
GC16562
PEAQX
NVP-AAM077
PEAQX(NVP-AAM 077) 是一种有效的、具有口服活性的 NMDA 拮抗剂,对人 NMDA 受体的 1A/2A(IC50=270 nM) 比 1A/2B(29,600 nM) 高 15 倍。 -
GC13445
LY2119620
3-氨基-5-氯-N-环丙基-4-甲基-6-[2-(4-甲基-1-哌嗪基)-2-氧代乙氧基]-噻吩并[2,3-B]吡啶-2-甲酰胺
A positive allosteric modulator of M2 and M4 mAChRs -
GC17627
Nitenpyram
烯啶虫胺
An insecticide -
GC10814
Promethazine HCl
盐酸异丙嗪
A histamine H1 receptor antagonist -
GC10300
Diphenidol HCl
盐酸地芬尼多; Difenidol hydrochloride
A muscarinic acetylcholine receptor antagonist -
GC11309
ARN2966
2-PMAP
An inhibitor of APP production and Aβ secretion -
GC11844
Pimavanserin
匹莫范色林; ACP-103
A 5-HT2A inverse agonist -
GC11963
Oxiracetam
奥拉西坦,ISF2522
An Analytical Reference Standard -
GC17047
Threo-methylphenidate hydrochloride
盐酸哌甲酯
盐酸苏哌甲酯(Threo-methylphenidate hydrochloride)是一种儿茶酚胺再摄取抑制剂,抑制多巴胺转运蛋白(DAT)和去甲肾上腺素转运蛋白(NET)。 -
GC10913
GTS 21 dihydrochloride
(3E)-3-[(2,4-二甲氧基苯基)亚甲基]-3,4,5,6-四氢-2,3'-联吡啶二盐酸盐,DMXB-A; DMBX-anabaseine
An agonist of α7-containing nAChRs -
GC16315
D-AP5
(R)-(-)-2-氨基-5-膦酰戊酸,D-2-Amino-5-Phosphonovaleric acid; D-APV
D-AP5是一种选择性N-甲基-D-天门冬胺酸(NMDA)受体拮抗剂,Kd 值为1.4μM。 -
GC16247
DCG IV
DCG IV 是 II 组 mGluRs 的有效激动剂,对 mGlu2R 和 mGlu3R 的 EC50 分别为 0.35 和 0.09 μM。
-
GC17950
MMPIP hydrochloride
A reversible allosteric antagonist of mGluR7
-
GC12703
Philanthotoxin 74
PhTx 74 dihydrochloride
An AMPA receptor antagonist -
GC17932
L-AP4
L(+)-2-氨基-4-膦酰基丁酸,L-APB
A selective Group III metabotropic glutamate receptor agonist -
GC10988
J 147
J 147 是一种非常有效的口服活性神经保护剂,用于增强认知能力。
-
GC12800
PAOPA
dopamine D2 receptor modulator
-
GC17095
ML 337
ML 337 是一种选择性和脑渗透性的 mGlu3 负变构调节剂,IC50 为 593 nM。
-
GC14869
ML 289
VU0463597
A negative allosteric modulator of mGlu3 -
GC10894
Methoxy-X04
Methoxy-X04是一种具有荧光性的刚果红和柯胺G的衍生物,不含酸性基团,分子量更小且亲脂性更强。
-
GC17385
KML 29
An inhibitor of MAGL
-
GC16776
QNZ 46
An antagonist of NR2C- and NR2D-subunit containing NMDA receptors
-
GC17585
VUF 10460
A histamine H4 receptor agonist
-
GC12959
SIB 1553A hydrochloride
A β4 subunit-selective nAChR agonist
-
GC14610
A 412997 dihydrochloride
Selective D4 agonist
-
GC14508
PTAC oxalate
muscarinic receptor ligand
-
GC12937
STF 083010
IRE1 Inhibitor I
An inhibitor of IRE1 endonuclease activity -
GC12739
A 484954
An eEF-2K inhibitor
-
GC15333
A 844606
α7 nAChR partial agonist
-
GC16242
SEN 12333
WAY-317538
An agonist of α7 nAChRs -
GC10045
MFZ 10-7
MFZ 10-7 是一种有效的 mGluR5 拮抗剂。
-
GC13052
SR 16584
Selective antagonist of α3β4 nicotinic acetylcholine receptors
-
GC12460
ADX 10059 hydrochloride
Negative allosteric modulator at mGlu5
-
GC13715
MK 0343
MRK-409
MK0343 (MRK-409) 是一种口服生物可利用的 GABAA 受体亚型选择性部分激动剂。 -
GC17821
VU 0365114
A positive allosteric modulator of muscarinic M5 receptors
-
GC11986
VU 0360223
CAY10651
A negative allosteric modulator of the mGlu5 receptor -
GC10238
MNI 137
MNI 137 是一种有效的、选择性的负变构调节剂,适用于 II 组 mGluR。
-
GC16643
VU 0285683
negative allosteric modulator of mGlu5 receptors
-
GC13290
CMPDA
A positive allosteric modulator of GluA2
-
GC11750
TC-N 22A
TC-N 22A 是一种有效的、选择性的、具有口服活性和脑渗透性的 mGlu4 PAM,在表达人 mGlu4 的 BHK 细胞中的 EC50 为 9 nM。
-
GC12485
Ro 67-7476
A positive allosteric modulator of mGluR1
-
GC10323
VU 0360172 hydrochloride
A positive allosteric modulator of mGluR5
-
GC14743
WY 45233 succinate
去甲文拉法辛(O-去甲文拉法辛)琥珀酸,O-Desmethylvenlafaxine succinate; Wy-45233 succinate
serotonin and noradrenalin reuptake inhibitor