Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for Neuroscience

Cat.No. 产品名称 Information
GC19346 Talampanel
(8R)-7-乙酰基-5-(4-氨基苯基)-8,9-二氢-8-甲基-7H-1,3-二氧杂环戊烯并[4,5-H][2,3]苯并二氮杂卓,GYKI-53773; LY-300164
An allosteric AMPA receptor antagonist
GC19318 SAGE-217
S-812217, SGE 797
A positive allosteric modulator of GABA_A receptors
GC19311 Ro 41-1049 hydrochloride Ro 41-1049 hydrochloride 是单胺氧化酶-A (MAO-A) 的可逆选择性抑制剂。
GC19310 Ro 25-6981 A potent, NR2B-selective NMDA receptor antagonist
GC19294 Piboserod
哌波色罗,SB-207266
A selective, potent 5-HT₄ receptor antagonist
GC19271 ONO-8590580 A negative allosteric modulator of α₅ subunit-containing GABA_A receptors
GC19258 Nastorazepide
Z-360
Nastorazepide (Z-360) 是一种选择性的口服 1,5-苯二氮卓衍生物胃泌素/胆囊收缩素 2 (CCK-2) 受体拮抗剂，具有潜在的抗肿瘤活性。
GC19221 Leucomethylene blue Mesylate
TRx0237 mesylate; Methylene blue leuco base mesylate
An inhibitor of tau aggregation
GC19217 Lanabecestat
AZD3293; LY3314814
An inhibitor of BACE1 and BACE2
GC19209 JNJ-63533054
3-氯-N-[2-氧代-2-[[(1S)-1-苯基乙基]氨基]乙基]苯甲酰胺
JNJ-63533054 是一种有效的选择性 hGPR139 激动剂，EC50 = 16nM。
GC19178 GSK189254A
GSK189254
A histamine H₃ receptor antagonist
GC19176 GSK163090 GSK163090 是一种有效的、选择性的和具有口服活性的 5-HT1A/1B/1D 受体拮抗剂，pKi 值分别为 9.4/8.5/9.7。
GC19118 Dasotraline hydrochloride
达索曲林盐酸盐,SEP-225289 hydrochloride
Dasotraline hydrochloride (SEP-225289 hydrochloride) 是一种三重再摄取抑制剂，可阻断多巴胺、去甲肾上腺素和血清素转运蛋白，IC50 值分别为 4、6 和 11 nM。
GC19117 Dasotraline
SEP 225289
Dasotraline 是一种三重再摄取抑制剂，可阻断多巴胺、去甲肾上腺素和血清素转运蛋白，IC50 值分别为 4、6 和 11 nM。
GC19057 Basmisanil
巴米沙尼,RG1662; RO5186582
A negative allosteric modulator of α₅ subunit-containing GABA_A receptors
GC19053 Azeliragon
阿齐瑞格; TTP488; PF-04494700
An inhibitor of RAGE
GC18962 U-92016A A 5-HT_1A receptor agonist
GC18935 NPC-15437 (hydrochloride) A selective PKC inhibitor
GC18923 URB937 A potent FAAH inhibitor
GC18914 Prostaglandin F2α Alcohol
AGN 190190, PGF2αOH, ZK 62717
A PGF_2α analog
GC18891 Malathion
NSC 6524

An organophosphate insecticide
GC18890 Emamectin B1a
依马菌素B1A
An insecticide
GC18875 GSK3β Inhibitor XVIII An inhibitor of GSK3β
GC18873 URB447 An Analytical Reference Standard
GC18869 Deoxyenterocin
5-Deoxyenterocin
A bacterial metabolite with diverse biological activities
GC18867 SER-601 A selective CB₂ receptor agonist
GC18866 MCHB-1
NMethylcyclohexyl benzimidazole analog 1
A CB₂ receptor agonist
GC18827 Supercinnamaldehyde A TRPA1 channel activator
GC18823 BMS 986187 A positive allosteric modulator of δ-opioid receptors
GC18817 3β-hydroxy-5-Cholestenoic Acid
3β-hydroxy-5-CA, Cholesterol-26-carboxylic Acid
An active cholesterol metabolite
GC18798 11-cis Retinal
11-cis Retinaldehyde, 11-cis Vitamin A aldehyde

An inverse agonist of opsin
GC18797 Thiothixene
氨砜噻吨
A typical antipsychotic
GC18788 Graphislactone A An antioxidant
GC18783 13,14-dihydro-15-keto Prostaglandin E1
13,14-二氢-15-酮-前列腺素E1
An inactive metabolite of PGE₁
GC18728 CJ-13610 An inhibitor of 5-LO
GC18707 Pimprinine
5-(1H-吲哚基)2-甲基噁唑
An alkaloid with diverse biological activities
GC18695 CB-86 An Analytical Reference Standard
GC18654 8-hydroxy Loxapine
8-OH Loxapine
A loxapine metabolite
GC18650 S-(5'-Adenosyl)-L-methionine (tosylate)
AdoMet, SAM, SAMe

S-Adenosyl-L-methioninetosylate(S-Adenosylmethioninetosylate)是通过蛋氨酸腺苷转移酶的作用由蛋氨酸和ATP内源性生产的，是一种重要的具有口服活性的甲基供体。
GC18648 Echothiophate (iodide)
碘依可酯,Echothiophate iodide
An AChE inhibitor
GC18638 α-Copaene
(-)-Copaene

A sesquiterpene
GC18637 11β-Prostaglandin F2α
9α,11βPGF2α, 11βPGF2α, 11epi PGF2α
The primary PGD₂ metabolite
GC18631 4BP-TQS An agonist of α7 subunit-containing nAChRs
GC18622 (2'S)-Nicotine-1-oxide
(2'S)-尼古丁氧化物
A nicotine metabolite
GC18596 (±)-2-propyl-4-Pentenoic Acid
2-丙基-4-五烯酸,2-Allylpentanoic Acid, 4-ene VPA
A metabolite of valproic acid
GC18582 5'-hydroxy Meloxicam
5'-羟基美洛昔康
A metabolite of meloxicam
GC18580 B355252 A neuroprotective agent
GC18579 FFN-102 (trifluoroacetate salt) A fluorescent probe to label dopaminergic cells
GC18573 Tafluprost ethyl amide
他氟乙酰胺
An analog of tafluprost
GC18568 JNJ-40418677 A modulator of γ-secretase