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Home >> Signaling Pathways >> Membrane Transporter/Ion Channel

Membrane Transporter/Ion Channel(跨膜转运)

  1. Cat.No. 产品名称 Information
  2. GC11448 Istaroxime

    PST-2744;PST 2744;PST2744

     Istaroxime (PST2744) 是一种有效的 Na+,K+-ATPase 抑制剂，IC50 为 0.11 μM。
  3. GC15823 Flecainide acetate

    氟卡胺; R-818

     An inhibitor of cardiac late sodium current
  4. GC11091 EVP-6124 hydrochloride

    (R)-7-氯-N-(奎宁环-3-基)苯并[B]噻吩-2-甲酰胺盐酸盐,EVP 6124 hydrochloride;EVP6124 hydrochloride

     A partial agonist of α7 subunit-containing nAChRs
  5. GC15941 EVP-6124

    EVP 6124;EVP6124

     A partial agonist of α7 subunit-containing nAChRs
  6. GC15264 Etifoxine hydrochloride

    盐酸艾替伏辛,Stresam;HOE 36-801

     A positive allosteric modulator of GABAA receptors
  7. GC13022 Esomeprazole Magnesium trihydrate

    埃索美拉唑镁三水合物; (S)-Omeprazole magnesium trihydrate; (-)-Omeprazole magnesium trihydrate

     An H+/K+-ATPase inhibitor
  8. GC17163 Elacridar hydrochloride

    依克立达盐酸盐,GF 120918A;GF120918A;GF-120918A

     An inhibitor of MRP-1 and BCRP
  9. GC17215 Elacridar

    依克立达; GF120918; GW0918; GG918; GW120918

     An inhibitor of MRP-1 and BCRP
  10. GC17918 Capsazepine

    辣椒平

     Capsazepine是瞬时受体电位香草素1（TRPV1）受体的特异性拮抗剂，IC50值为562 nM。
  11. GC14065 Capsaicin

    辣椒素; (E)-Capsaicin

     辣椒素是一种高度选择性的瞬时受体电位阳离子通道激动剂，亚家族 V，成员 1 (TRPV1)，一种配体门控的非选择性阳离子通道，优先在小直径感觉神经元上表达 < /sup>。
  12. GC10206 Bitopertin

    比托派汀; RG1678; RO4917838

     An inhibitor of GlyT1
  13. GC10680 AR-C155858

    (S)-6-[(3,5-二甲基-1H-吡唑-4-基)甲基]-5-[(4-羟基异唑烷-2-基)羰基]-1-异丁基-3-甲基噻吩并[2,3-D]嘧啶-2,4(1H,3H)-二酮,AR C155858

     AR-C155858是一种强效的单羧酸转运蛋白1（MCT1）抑制剂，Ki值为2.3nM，也能抑制MCT2，Ki值>10nM。
  14. GC13164 Ampalex

    安帕来斯; BDP 12

     An AMPA receptor modulator
  15. GC14916 Acamprosate calcium

    阿坎酸钙,Calcium N-acetylhomotaurinate; Campral EC

     An NMDA modulator
  16. GC15014 A-867744

    4-[5-(4-氯苯基)-2-甲基-3-丙酰基吡咯-1-基]苯磺酰胺,A 867744;A867744

     A positive allosteric modulator of α7 nAChRs
  17. GC11842 A-740003

    N-[1-[[(氰基氨基)(5-喹啉亚氨基)甲基]氨基]-2,2-二甲基丙基]-3,4-二甲氧基苯乙酰胺,A 740003;A740003

     A selective P2X7 antagonist
  18. GC17710 A-317491

    A 317491;A317491

     A P2X3 and P2X2/3 receptor antagonist
  19. GC13733 A 438079 hydrochloride An antagonist of the nucleotide receptor P2X7
  20. GC17212 A 438079

    3-[[5-(2,3-二氯苯基)-1H-四唑-1-基]甲基]吡啶

     An antagonist of the nucleotide receptor P2X7
  21. GC16616 (+)-MK 801

    Dizocilpine maleate;Dizocilpine hydrogen maleate;(+)-MK 801;MK 801

     强效 NMDA 拮抗剂
  22. GC16149 Topiramate

    托吡酯; McN 4853; RWJ 17021

     An anticonvulsant
  23. GC16444 Rosiglitazone

    罗格列酮; BRL 49653

     Rosiglitazone是一种具有口服活性的过氧化物酶体增殖物活化受体γ（PPARγ ）选择性激动剂，选择性地激活含有PPARγ配体结合域（LBD）的嵌合体，而不是PPARα和PPARδ，EC50为60 nM，Kd为40 nM。
  24. GC11318 Rosiglitazone maleate

    马来酸罗格列酮; BRL 49653C

     A PPARγ agonist
  25. GC15570 Tariquidar

    N-[2-[[4-[2-(6,7-二甲氧基-3,4-二氢-1H-异喹啉-2-基)乙基]苯基]氨基甲酰基]-4,5-二甲氧基苯基]喹啉-3-甲酰胺,XR9576, XR 9576, XR-9576,Tariquidar

    A P-glycoprotein inhibitor
  26. GC10240 Atazanavir sulfate (BMS-232632-05)

    硫酸阿扎那韦; BMS-232632 sulfate

     An inhibitor of HIV-1 protease
  27. GC12945 Atazanavir

    阿扎那韦; BMS-232632

    An inhibitor of HIV-1 protease
  28. GN10122 Linalool

    芳樟醇

     A monoterpene alcohol with diverse biological activities
  29. GN10267 Loureirin B

    龙血素 B

     A flavonoid with diverse biological activities
  30. GN10747 Lannaconitine

    刺乌头碱

     A diterpene alkaloid with diverse biological properties
  31. GN10216 Shikonin

    紫草素; C.I. 75535; Isoarnebin 4

     Shikonin是一种含醌的天然产物。Shikonin是一种有效的TMEM16A氯离子通道抑制剂，IC50为6.5μM。
  32. GN10254 Ginsenoside Rc

    人参皂苷 Rc; Panaxoside Rc

     A saponin with diverse biological activities
  33. GN10715 Catharanthine Tartrate

    酒石酸长春质碱; (+)-3,4-Didehydrocoronaridine Tartrate

     An indole alkaloid with diverse biological activities
  34. GN10812 Acacetin

    金合欢素; 5,7-Dihydroxy-4'-methoxyflavone

     A flavonoid
  35. GN10612 (+)- Praeruptorin C

    白花前胡丙素

     (+)- Praeruptorin C 是前胡的主要生物活性成分（也称为白花前胡）。
  36. GN10311 N－Methylcytisine

    N-甲基野靛碱,Caulophylline

     An alkaloid with diverse biological activities
  37. GN10144 Oleandrin

    欧夹竹桃苷; PBI-05204

     A glycoside with diverse biological activities
  38. GN10809 Tanshinone IIA sulfonate sodium

    丹参酮IIA磺酸盐; Sodium Tanshinone IIA sulfonate; Tanshinone IIA sodium sulfonate

     A tanshinone IIA derivative with immunomodulatory activity
  39. GN10517 Ginsenoside Rf

    人参皂苷 Rf; Panaxoside Rf

     A natural steroid glycoside with diverse effects
  40. GN10445 (-)-pareruptorin A

    (±)-白花前胡甲素

     (-)-pareruptorin A 是 cis-khellactone (CKL) 的二酯化产物，是前胡的主要活性成分，由前胡 (伞形科) 的干燥根组成。
  41. GN10251 Ginkgolide A

    银杏内酯A; BN-52020

     A terpenoid lactone with diverse biological activities
  42. GN10029 Phloridzin

    根皮苷; Floridzin; NSC 2833

     An inhibitor of sodium-glucose cotransporters
  43. GN10779 Reserpine

    利血平

     Irreversible inhibitor of VMAT1 and VMAT2
  44. GN10437 Imperatorin

    欧前胡素; Ammidin

     A furanocoumarin with diverse biological activities
  45. GN10446 Tetrandrine

    汉防己甲素; NSC-77037; d-Tetrandrine

     An alkaloid with diverse biological activities
  46. GN10126 Cytisine

    金雀花碱; Cytisine; Sophorine; Baptitoxine

     An alkaloid and a partial agonist of nAChRs
  47. GN10792 Caffeic acid

    咖啡酸

     An inhibitor of 5-LO
  48. GN10020 Piperine

    胡椒碱; Bioperine; 1-Piperoylpiperidine

     A natural alkaloid with diverse biological actions
  49. GN10156 Ginsenoside Rb1

    人参皂苷 Rb1; Gypenoside III

     A triterpene saponin with diverse biological activities
  50. GN10549 Ginsenoside Rd

    人参皂苷 Rd; Gypenoside VIII

     A natural steroid glycoside with diverse effects
  51. GN10799 20(S)-Ginsenoside Rg3

    20(S)-人参皂苷 Rg3; 20(S)-Propanaxadiol; S-ginsenoside Rg3

     20(S)-Ginsenoside Rg3是从人参中提取的稀有人参皂苷（Na+：IC50 = 32.2±4.5μM；hKv1.4：IC50 = 32.6±2.2μM）。

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