Cell Cycle/Checkpoint(细胞周期/检查点)
Cell Cycle
Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0. read more
Products for Cell Cycle/Checkpoint
- ATM/ATR(28)
- Aurora Kinase(52)
- Cdc42(4)
- Cdc7(3)
- Chk(13)
- c-Myc(20)
- CRM1(8)
- Cyclin-Dependent Kinases(69)
- E1 enzyme(1)
- G-quadruplex(11)
- Haspin(6)
- HMTase(1)
- Kinesin(23)
- Ksp(4)
- Microtubule/Tubulin(215)
- Mps1(13)
- Mitotic(7)
- RAD51(13)
- ROCK(59)
- Rho(13)
- PERK(10)
- PLK(34)
- PTEN(6)
- Wee1(6)
- PAK(20)
- Arp2/3 Complex(8)
- Dynamin(10)
- ECM & Adhesion Molecules(40)
- Cytoskeleton & Motor Proteins(53)
- Endomembrane System & Vesicular Trafficking(26)
- G1(38)
- Genotoxic Stress(18)
- G2/M(26)
- G2/S(10)
- Inositol Phosphates(20)
- Proteolysis(98)
- Cellular Chaperones(8)
- Cat.No. 产品名称 Information
- GC52029 2-Aminoflubendazole A metabolite of flubendazole
- GC52007 N-hydroxylamine Dapsone An active metabolite of dapsone
- GC49915 Hexa-D-Arginine (trifluoroacetate salt) A furin inhibitor
- GC49914 Pt(II)-NHC Complex 2C An inducer of immunogenic cancer cell death
- GC49913 Davunetide (acetate) A neuroprotective ADNP-derived peptide
- GC49863 Cytarabine 5′-monophosphate An active metabolite of cytarabine
- GC49855 Harmalol (hydrochloride hydrate) A β-carboline alkaloid and an active metabolite of harmaline
- GC49836 Benoxaprofen An NSAID
- GC49835 Tumulosic Acid A triterpene with diverse biological activities
- GC49804 Acridine An azaarene
- GC49781 Benomyl A carbamate pesticide
- GC49773 Albendazole sulfone-d3 An internal standard for the quantification of albendazole sulfone
- GC49771 rac-Hesperetin-d3 An internal standard for the quantification of hesperetin
- GC49757 Bazedoxifene N-oxide An oxidative degradation product of bazedoxifene
- GC49751 Lefamulin A pleuromutilin antibiotic
- GC64278 RP-3500 RP-3500 (Camonsertib, ATR inhibitor) is a highly potent and selective inhibitor of ATR kinase with an IC50 of 1 nM.
- GC64273 AMXI-5001 AMXI-5001 是一种有效的、具有口服活性的 parp1/2 和微管聚合抑制剂。MXI-5001 对多种人类癌细胞表现出选择性抗肿瘤细胞毒性,其 IC50s 比现有的临床 PARP1/2 抑制剂低得多。AMXI-5001 诱导已建立的肿瘤完全消退,包括非常大的肿瘤。
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GC64085
KIF18A-IN-1
KIF18A-IN-1 是一种有丝分裂驱动蛋白 KIF18A 的抑制剂,具有抗肿瘤活性。详细信息请参考专利文献 WO2021026098A1 中的化合物 100-13。
- GC64019 Sovilnesib AMG 650 (Sovilnesib) is an oral, first in class, selective kinesin-like protein KIF18A inhibitor, can be used for the research of cancer.
- GC63977 BMVC2 BMVC2 (o-BMVC) 是 BMVC 的双取代咔唑衍生物,是一种 G 四联体 (G4) 稳定剂。
- GC63845 Eribulin-d3 mesylate Eribulin-d3 mesylate 是 Eribulin mesylate 的氘代物。Eribulin mesylate 是靶向微管 (microtubule) 的抗癌剂,可用于研究癌症。
- GC49744 GRP94 Monoclonal Antibody (Clone 9G10) For immunochemical detection of GRP94
- GC49742 Hsf1 Monoclonal Antibody (Clone 10H8) For immunochemical analysis of Hsf1
- GC49740 Brevetoxin 3 A neurotoxin
- GC49736 10-acetyl Docetaxel A derivative of paclitaxel and an inhibitor of microtubule depolymerization
- GC49735 Thallos AM A cell-permeable fluorescent thallium indicator
- GC49724 BIO-1211 (trifluoroacetate salt) A peptide inhibitor of α4β1 integrin
- GC49723 SenTraGor™ Cell Senescence Reagent A cellular senescence detection reagent
- GC49716 Cyclo(RGDyK) (trifluoroacetate salt) A cyclic peptide ligand of αVβ3 integrin
- GC49713 SIKVAV (acetate) A laminin α1-derived peptide
- GC49709 cyclo(RGDyC) (trifluoroacetate salt) A cyclic pentapeptide
- GC49704 Ac-FLTD-CMK (trifluoroacetate salt) An inhibitor of caspase-1, -4, -5, and -11
- GC49702 Papain Inhibitor (trifluoroacetate salt) A peptide inhibitor of papain
- GC49699 Acetyl Tetrapeptide-9 (acetate) A synthetic signal peptide
- GC49695 FKBP52 Monoclonal Antibody (Clone Hi52C) For immunochemical analysis of FKBP52
- GC49687 Goralatide (acetate) A tetrapeptide regulator of hematopoiesis
- GC49685 Trifluoroacetyl Tripeptide-2 (acetate) A peptide inhibitor of pancreatic and neutrophil elastases
- GC49684 Dabigatran-13C-d3 An internal standard for the quantification of dabigatran
- GC49682 Dabigatran-d3 An internal standard for the quantification of dabigatran
- GC49674 Schizandrin A lignan with diverse biological activities
- GC49605 H-Gly-Pro-Hyp-OH (acetate) A peptide DPP-4 inhibitor
- GC49547 L-Glutamic Acid γ-p-Nitroanilide (hydrate) A colorimetric substrate for γ-glutamyl transpeptidase
- GC49532 S-(1,2-Dichlorovinyl)-Cysteine (hydrochloride) A nephrotoxin and metabolite of trichloroethylene
- GC49491 N′-Nitrosonornicotine-d4 An internal standard for the quantification of N'-nitrosonornicotine
- GC49482 (±)-Nornicotine-d4 An internal standard for the quantification of (±)-nornicotine
- GC49471 LAMP1 Monoclonal Antibody (Clone Ly1C6) For immunochemical analysis of LAMP1
- GC49469 IPG-1 TMA A cell-impermeable fluorescent potassium indicator
- GC49468 IPG-1 AM A cell-permeable fluorescent potassium indicator
- GC49466 IPG-2 TMA A cell-impermeable fluorescent potassium indicator
- GC49463 IPG-2 AM A cell-permeable fluorescent potassium indicator