Neuroscience(神经科学)

Neuroscience
Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more
Products for Neuroscience
- 5-HT Receptor(420)
- AChR(53)
- AChE(100)
- Alzheimer(107)
- Amyloid β(118)
- BACE(4)
- CGRP (33)
- COX(294)
- DAPK(7)
- Dopamine Receptor(290)
- GABA Receptor(155)
- Gap Junction(16)
- GluR(116)
- Histamine(2)
- Histamine Receptor(236)
- mPEGS-1(4)
- Muscarinic Receptor(41)
- Neuroscience Peptides(38)
- Nicotinic Receptor(62)
- P2 Receptor(2)
- P2X7 receptor(3)
- SSRIs(5)
- Substance P/NK1 Receptor(20)
- NMDA(2)
- Beta-secretase(25)
- CaMK(32)
- Dopamine Transporter(20)
- Monoamine Oxidase(91)
- Serotonin Transporter(57)
- nAChR(100)
- iGluR(155)
- Neurokinin Receptor(75)
- MCHR1 (GPR24)(16)
- mAChR(183)
- GPR139(4)
- Cholecystokinin Receptor(25)
- Behavioral Neuroscience(353)
- DREADD(1)
- Huntington(14)
- Neuroendocrinology(64)
- Neuroprotection(117)
- Ophthalmology(158)
- Pain Research(229)
- Parkinson(73)
- Prion(7)
- Seizure Disorders(94)
- Cholinesterases(13)
- Tau Protein(4)
- Neurodegenerative Disorders(5)
- Cholinesterase (ChE)(3)
- Amyloid-β(9)
- γ-secretase(1)
- Ischemia(3)
- Cat.No. 产品名称 Information
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GC16903
GR 103691
A dopamine D3 receptor antagonist
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GC10219
AF-DX 116
11-((2-((二乙氨基)甲基)-1-哌啶基)乙酰基)-5,11-二氢-(6H)-吡啶并[2.3-B][1.4]苯并二氮杂-6-酮,AF-DX 116
A muscarinic M2 receptor antagonist -
GC18079
CFM-2
CFM-2 是一种有效且选择性的非竞争性 AMPAR 拮抗剂。
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GC15226
SKF 89976A hydrochloride
1-(4,4-二苯基-3-丁烯基)-3-哌啶盐酸盐,d,l-SKF89976A hydrochloride
SKF 87699A hydrochloride 是一种选择性 GABA 转运蛋白 (GAT-1) 抑制剂,对 CHO 细胞中的 GAT-1、GAT-2 和 GAT-3 的 IC50 分别为 0.28 μM、137.34 μM 和 202.8 μM。 -
GC17333
(R)-(+)-8-Hydroxy-DPAT hydrobromide
5-HT1A serotonin receptor agonist
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GC11771
(RS)-APICA
(RS)-APICA 是一种选择性 II 组代谢型谷氨酸受体 (mGluR II) 拮抗剂。
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GC13388
Zolantidine dimaleate
H2 receptor antagonist
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GC17634
PD 168077 maleate
A dopamine D4 receptor agonist
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GC17877
(-)-Quinpirole hydrochloride
(-)-LY 171555
(-)-Quinpirole hydrochloride ((-)-LY 171555) 是一种多巴胺 D2/D3 受体的高亲和力激动剂。 -
GC12532
CHPG
Chlorohydroxyphenylglycine, CHPG
A potent and selective mGluR5 agonist -
GC12863
1-BCP
Piperonylic acid piperidide
A positive allosteric modulator of AMPA receptors -
GC11602
Piribedil dihydrochloride
盐酸吡贝地尔;盐酸双哌嘧啶;盐酸泰舒达
A dopamine receptor agonist -
GC13678
Methyllycaconitine citrate
甲基牛扁亭柠檬酸盐; MLA
Methyllycaconitine citrate (MLA),一种从飞燕草种子中分离出来的降二萜类生物碱。 -
GC18134
CPCCOEt
An mGluR1b antagonist
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GC17383
PHCCC
N-苯基-7-(羟基亚胺基)环丙烯并[B]苯并吡喃-1A-甲酰胺
PHCCC 是 I 组 mGluR 拮抗剂,IC50 为 3 μM。 PHCCC 是 mGlu4 受体的选择性正调节剂。抗帕金森效应。 -
GC13192
E4CPG
(RS)-ECPG
An antagonist of mGluR1 and mGluR2 -
GC16553
N-Desmethylclozapine
N-去甲基氯氮平; Norclozapine; Desmethylclozapine; Normethylclozapine
An active metabolite of clozapine -
GC15619
L-741,626
A dopamine D2 receptor antagonist
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GC15703
Chlorisondamine diiodide
A long-lasting antagonist of nAChRs and ganglion blocker
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GC12632
Cyanopindolol hemifumarate
5-HT1A/1B antagonist and β-adrenoceptor antagonist
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GC11984
Isamoltane hemifumarate
Isamoltane hemifumarate 是 5-HT1B 受体的选择性拮抗剂,抑制 [125I]ICYP 与大鼠脑膜中 5-HT1B 识别位点的结合,IC50 为 39 nM。
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GC12100
CPPG
(RS)-CPPG
An antagonist of group II and group III mGluRs -
GC17326
EGLU
(2S)-α-Ethylglutamic acid; (2S)-α-EGLU
EGLU ((2S)-α-Ethylglutamic acid; (2S)-α-EGLU) 是一种有效的竞争性 mGluR-2 受体拮抗剂。 -
GC13728
SYM 2206
8-(4-氨基苯基)-5-甲基-N-丙基-1,3-二氧杂环戊烯并[4,5-G]酞嗪-6(5H)-甲酰胺
SYM 2206 是一种有效的非竞争性 AMPA 受体拮抗剂,IC50 为 1.6 μM。 -
GC12241
NS 398
抑制剂
A selective COX2 inhibitor -
GC14891
MM 77 dihydrochloride
MM 77 dihydrochloride 是一种有效的 5-HT1A 受体的突触后拮抗剂。
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GC12966
Immepip dihydrobromide
4-(1H-咪唑基-4-甲基)哌啶二氢溴酸盐
A histamine H3 receptor agonist -
GC10892
SCH 23390 hydrochloride
R-(+)-SCH-23390 hydrochloride
SCH 23390 hydrochloride 是一种高效的选择性多巴胺 D1 样受体拮抗剂,对 D1 和 D5 多巴胺受体亚型的 K(i) 分别为 0.2 和 0.3 nM。 -
GC15606
3α-Bis-(4-fluorophenyl) methoxytropane hydrochloride
dopamine uptake and transport inhibitor
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GC12641
3-CPMT
dopamine uptake inhibitor
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GC14822
Remoxipride hydrochloride
瑞莫必利盐酸盐
An atypical antipsychotic -
GC14810
L-701,324
7-氯-4-羟基-3-(3-苯氧基)苯基-2(1H)-喹啉
An NMDA receptor antagonist -
GC14146
AIDA
AIDA
AIDA (AIDA) 是一种刚性(羧基苯基)甘氨酸衍生物,是一种相对有效和选择性的 I 组代谢型谷氨酸受体 (mGlu1a) 拮抗剂,IC50 为 214 μM. -
GC16101
SYM 2081
(2S,4R)-4-甲基谷氨酸
SYM 2081 是一种高亲和力配体和有效的红藻氨酸受体激动剂,抑制 [3H]-红藻氨酸结合,IC50 为 35 nM,对红藻氨酸受体的选择性分别是 AMPA 和 NMDA 受体的近 3000 倍和 200 倍[1 ]。 -
GC17477
5-Nonyloxytryptamine oxalate
A potent 5-HT1Dβ receptor agonist
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GC18128
L-732,138
An NK1 receptor antagonist
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GC11428
MTPG
MTPG 是一种有效的 mGluR2 和 mGluR3 拮抗剂。
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GC13548
MSPG
mGlu receptor antagonist
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GC15769
MPPG
MPPG 是一种有效的选择性 L-AP4 敏感受体拮抗剂,kD 值为 9.2 μM,正在新生大鼠脊髓上进行测试。
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GC16858
(S)-3,5-DHPG
(S)-3,5-二羟基苯基甘氨酸
A selective agonist of group I mGluRs -
GC17185
MSOP
MSOP 是一种选择性 III 族代谢型谷氨酸受体拮抗剂,对 L-AP4 敏感的突触前 mGluR 的表观 KD 为 51 μM。
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GC12427
8-Hydroxy-PIPAT oxalate
5-HT1A receptor agonist
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GC12265
Iodophenpropit dihydrobromide
A histamine H3 receptor antagonist
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GC12870
(+)-UH 232 maleate
顺-(+)-5-甲氧基-1-甲基-2-(二正丙基氨基)萘满马来酸
D2 antagonist -
GC10490
Clobenpropit dihydrobromide
丙酸倍氯松二溴酸盐溶液,1000PPM,VUF 9153
A selective histamine H3 receptor antagonist -
GC14311
4-Phenyl-1,2,3,4-tetrahydroisoquinoline hydrochloride
dopamine release inhibitor
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GC11220
Imetit dihydrobromide
S-[2-(4(5)-咪唑基)乙基]异硫脲氢溴酸盐,VUF 8325 dihydrobromide; SKF 91105 dihydrobromide
A histamine H3 and H4 receptor agonist
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GC16916
7-Hydroxy-PIPAT maleate
D3 receptor agonist
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GC11571
MAP4
(S)-2-氨基-2-甲基-4-磷酰丁酸
MAP4 在某些电生理系统中是一种选择性 III 组 mGluR 拮抗剂。
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GC16574
7-Hydroxy-DPAT hydrobromide
A dopamine D3 receptor agonist