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Home >> Signaling Pathways >> Neuroscience

Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for  Neuroscience

  1. Cat.No. 产品名称 Information
  2. GC12510 BINA

    3'-[[(2-环戊基-6,7-二甲基-1-氧代-2,3-二氢-1H-茚-5-基)氧基]甲基]联苯-4-羧酸,BINA

     A positive allosteric modulator of mGluR2
  3. GC12371 JNJ 10181457 dihydrochloride Histamine H3 receptor antagonist
  4. GC14620 L 760735 L 760735 是一种高亲和力、选择性和口服活性的 NK1 受体拮抗剂，对人 NK1 受体的 IC50 为 0.19 nM。
  5. GC12899 CBiPES hydrochloride positive allosteric modulator of the mGlu2 receptor
  6. GC14593 GSK 789472 hydrochloride dopamine D3 receptor antagonist and D2 partial agonist
  7. GC10973 SC 236

    4-(5-(4-氯苯基)-3-(三氟甲基)-1H-

     A potent, selective COX-2 inhibitor
  8. GC11810 PG 01037 dihydrochloride A selective dopamine D3 receptor antagonist
  9. GC12119 CCMI

    AVL-3288; UCI-4083

     CCMI (AVL-3288) 是一种有效且选择性的 α7 nAChR 阳性变构调节剂，不通过正构位点结合或激活 α7 nAChRs，并导致激动剂诱导的 α7 nAChRs 电流显着正向调节。
  10. GC11121 A 943931 dihydrochloride Antagonist of histamine H4 receptor,potent and selective
  11. GC11617 Pristimerin

    扁塑藤素,Celastrol methyl ester

     Potent, selective inhibitor of monoacylglycerol lipase
  12. GC10464 VU 0255035

    N-(3-氧代-3-(4-(吡啶-4-基)哌嗪-1-基)丙基)苯并[C][1,2,5]噻二唑-4-磺酰胺,VU 255035

     A selective muscarinic M1 receptor antagonist
  13. GC11395 7-Chlorokynurenic acid sodium salt

    7-氯犬尿喹啉酸钠盐,7-CKA sodium salt

     A glycine-site selective NMDA receptor antagonist
  14. GC11997 (RS)-MCPG disodium salt group I/group II metabotropic glutamate receptor antagonist
  15. GC17963 CHPG Sodium salt CHPG 钠盐是一种选择性 mGluR5 激动剂，可通过 BV2 小胶质细胞中的 TSG-6/NF-κB 通路减弱 SO2 诱导的氧化应激和炎症。
  16. GC17743 A 987306 A 987306 是一种有效的、可口服的组胺 H4 拮抗剂，对大鼠 H4 和人 H4 的 Kis 分别为 3.4 nM 和 5.8 nM。
  17. GC15990 VU 0238429

    HY-12157, ML129

     A muscarinic M5 receptor positive allosteric modulator
  18. GC11757 3-Bromocytisine

    3-Br-cytisine

     3-Bromocytisine (3-Br-cytisine) 是一种有效的 nACh 受体激动剂，对 hα4β4、hα4β2 和 hα7-nACh 的 IC50 分别为 0.28、0.30 和 31.6 nM。
  19. GC14280 PD 168568 dihydrochloride PD 168568 dihydrochloride 是一种具有口服活性的选择性 D4 多巴胺受体拮抗剂，Ki 为 8.8 nM。
  20. GC15910 S 24795

    2-[2-(4-溴苯肼)-2-乙氧基]-1-甲基碘吡啶

     S 24795 是 α7 nAChR 的部分激动剂，可改善老年小鼠的记忆功能，用于治疗与衰老相关的记忆障碍。
  21. GC11970 YM 202074 metabotropic glutamate receptor type 1 (mGlu1) antagonist
  22. GC15950 CGP 52411

    DAPH

     A phthalimide with diverse biological activities
  23. GC15763 PNU 177864 hydrochloride dopamine D3 receptor antagonist
  24. GC17846 SNAP 94847 hydrochloride An antagonist of MCH1
  25. GC17604 NPEC-caged-(1S,3R)-ACPD group I and II mGlu receptor agonist
  26. GC11554 NPEC-caged-(S)-3,4-DCPG mGlu8a agonist
  27. GC12593 Desformylflustrabromine hydrochloride

    Deformylflustrabromine hydrochloride; dFBr hydrochloride

     Desformylflustrabromine hydrochloride 是 α4β2 神经元烟碱乙酰胆碱受体 (nAChR) 的选择性激动剂，pEC50 为 6.48。
  28. GC17749 VU 1545 VU 1545 是一种代谢型谷氨酸受体 5 正变构调节剂 (mGluR5 PAM)，Ki 为 156 nM，EC50 为 9.6 nM。
  29. GC14003 VU 0155041 sodium salt A selective positive allosteric modulator of mGluR4
  30. GC14694 NGD 94-1 High affinity D4 receptor ligand
  31. GC14097 LY 487379 hydrochloride LY 487379 hydrochloride 是一种选择性人 mGluR2 正变构调节剂 (PAM)。
  32. GC12699 (±)-LY 395756 ligand for mGlu2 and mGlu3 receptor
  33. GC17531 Z-Cyclopentyl-AP4 Group III mGlu receptor agonist
  34. GC15198 VU 0155041 A selective positive allosteric modulator of mGluR4
  35. GC10605 LY 354740

    (1S,2S,5R,6S)-2-氨基二环[3.1.0]己烷-2,6-二羧酸,LY354740; Eglumetad

    An agonist of mGluR2 and mGluR3
  36. GC10422 CDPPB

    3-氰基-N-(1,3-二苯基吡唑-5-基)苯甲酰胺

     A positive allosteric modulator of mGluR5
  37. GC16927 bPiDDB Orthosteric neuronal nicotinic acetylcholine receptor (nAChR) antagonist
  38. GC15660 SB 399885 hydrochloride A 5-HT6 receptor antagonist
  39. GC10725 VU 10010 VU 10010 是一种有效的、高选择性的变构 M4 mAChR 增强剂，EC50 为 400 nM。
  40. GC12678 PHA 568487 PHA 568487 是一种选择性 α7 烟碱型乙酰胆碱受体 (α-7 nAchR) 激动剂。
  41. GC13405 DMCM hydrochloride DMCM hydrochloride 是苯二氮卓类的非选择性全反向激动剂。
  42. GC16068 A 841720 An mGluR1 antagonist
  43. GC13064 NS 1738

    NSC 213859

     A positive allosteric modulator of α7-containing nAChRs
  44. GC14495 CX 546

    苯并二氧六环-6-(1-哌啶基)甲酰胺

     CX 546 是第一代选择性苯甲酰胺型正 AMPAR 调节剂。
  45. GC17010 Methimepip dihydrobromide histamine H3 receptor agonist
  46. GC11704 Ro 64-5229 mGlu2 antagonist
  47. GC10453 CP 96345 CP 96345 是一种特异性、高效、具有口服活性的速激肽和 P 物质受体非肽抑制剂。
  48. GC10329 Mecamylamine hydrochloride

    盐酸美加明

     A noncompetitive nicotinic antagonist
  49. GC16324 Nefazodone hydrochloride

    萘法唑酮盐酸盐,BMY-13754; MJ-13754-1

     A serotonin, norepinephrine, and dopamine reuptake inhibitor
  50. GC11013 U 93631 A GABAA receptor ligand
  51. GC15160 TC 2559 difumarate A partial agonist for α4β2 subunit-containing nAChRs

Items 3101 to 3150 of 3961 total

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