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Home >> Signaling Pathways >> Neuroscience

Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for  Neuroscience

  1. Cat.No. 产品名称 Information
  2. GC11563 NPS 2390

    Type I metabotropic glutamate receptor antagonist
  3. GC10484 3-pyr-Cytisine

    α4β2 receptors agonist
  4. GC11046 JNJ 5207852 dihydrochloride Selective, non-imidazole histamine H3R antagonist
  5. GC11256 SR 140333

    SR140333

     SR 140333 (SR140333) 是一种有效的、选择性的、竞争性的、非肽速激肽 NK1 受体拮抗剂。
  6. GC13684 S 18986 A positive allosteric modulator of AMPA receptors
  7. GC16528 MRK 016 An inverse agonist of α5 subunit-containing GABAA receptors
  8. GC15832 GSK 264220A An endothelial lipase inhibitor
  9. GC18083 CP 99994 dihydrochloride A nonpeptide NK1 receptor antagonist
  10. GC16251 NAD 299 hydrochloride 选择性、高亲和力的 5-HT1A 受体拮抗剂
  11. GC18063 YM 230888 Selective mGlu1 antagonist
  12. GC13007 PEPA A positive allosteric modulator of AMPA receptors
  13. GC14392 SB 242084

    6-氯-2,3-二氢-5-甲基-N-[6-[(2-甲基-3-吡啶基)氧]-3-吡啶基]-1H-吲哚-1-酰胺盐酸盐

     Specific antagonist of 5-HT2C
  14. GC17817 SC 58125

    1-[(4-甲基磺酰基)苯基]-3-三氟甲基-5-(4-氟苯基)吡唑

     A selective COX-2 inhibitor
  15. GC11384 BTS 54-505 hydrochloride

    1-[1-(4-氯苯基)环丁基]-3-甲基丁胺盐酸盐

     Potent SNRI,sibutramine metabolite
  16. GC17636 Noladin ether

    2AG ether, Noladin

     A potent and selective agonist of the CB1 receptor and GPR55
  17. GC13599 L-733,060 hydrochloride L-733,060 hydrochloride 是一种有效的速激肽 NK1 受体拮抗剂。
  18. GC12435 ACPT-I An mGluR4a and mGluR8 agonist
  19. GC13036 L-741,742 hydrochloride highly potent and selective D4 dopamine receptor antagonist
  20. GC14569 L-745,870 trihydrochloride L-745,870 trihydrochloride 是一种有效的、选择性的、脑渗透性和口服活性的多巴胺 D4 受体拮抗剂，Ki 为 0.43 nM。
  21. GC10888 SCH 50911 SCH 50911, (+)-(S)-5,5-dimethylmorpholinyl-2-乙酸，一种选择性、口服活性和竞争性 γ-氨基丁酸 B GABA(B) 受体拮抗剂，与 GABA(B ) 受体，IC50 为 1.1 μM。
  22. GC17527 (+)-Dihydrexidine hydrochloride

    (+)-DAR-0100 hydrochloride

    (+)-Dihydrexidine hydrochloride ((+)-DAR-0100 hydrochloride) 是一种多巴胺 D1 受体激动剂，EC50 为 72± 21 nM。
  23. GC11330 Tiotidine

    硫替丁,ICI 125211

     Tiotidine (ICI 125211) 是一种有效的选择性组胺 H2 受体拮抗剂（豚鼠右心房的 pA2=7.3-7.8）。
  24. GC14873 2-CMDO Dopamine D2-like receptor antagonist
  25. GC14742 DPPE fumarate

    DPPE fumarate

     An AEBS ligand
  26. GC11809 (R)-(-)-α-Methylhistamine dihydrobromide

    (R)-(-)-α-甲基组胺二氢溴酸盐

     (R)-(-)-α-Methylhistamine dihydrobromide 是一种有效的、选择性的、可穿透脑的 H3 组胺受体激动剂，Kd 为 50.3 nM。
  27. GC11176 2-Methyl-5-hydroxytryptamine hydrochloride

    2-Methyl-5-hydroxytryptamine hydrochloride; 2-Methylserotonin hydrochloride; 2-Me-HT hydrochloride

     2-Methyl-5-hydroxytryptamine hydrochloride (2-Methyl-5-hydroxytryptamine hydrochloride) 是一种有效的选择性 5-HT3 受体激动剂。
  28. GC16557 LY 379268 disodium salt group II mGlu receptor agonist
  29. GC14722 LY 2389575 hydrochloride negative allosteric modulator of mGlu3
  30. GC12237 SIB 1508Y maleate neuronal nicotinic ACh receptor agonist
  31. GC13537 A 331440 dihydrochloride H3 receptor antagonist,non-imidazole,high affinity
  32. GC17826 Tegaserod maleate

    马来酸替加色罗; SDZ-HTF-919; HTF-919

     A potent 5-HT4 agonist
  33. GC12684 NCX 4040

    NO-Aspirin

     NCX 4040 (NO-Aspirin) 是一种非甾体抗炎药 (NSAID)，是一种一氧化氮 (NO) 释放形式的阿司匹林。
  34. GC17289 VU 29 VU 29 是代谢型谷氨酸 5 (mGlu5) 受体的正变构调节剂（对于 rmGluR5，EC50\u003d9 nM 和 Ki\u003d244 nM）。
  35. GC17841 JHW 007 hydrochloride Dopamine uptake inhibitor
  36. GC14383 Ro 01-6128 A positive allosteric modulator of mGLUR1
  37. GC14172 Ro 67-4853 A positive allosteric modulator of mGlu1 receptors
  38. GC17805 A 582941 A 582941 是 α7 nAChR 的有效、选择性和脑穿透性部分激动剂，在大鼠脑膜和人类额叶皮层中的 Kis 分别为 10.8 和 16.7 nM。
  39. GC16655 VU 0357017 hydrochloride

    CID-25010775

     An M1 muscarinic acetylcholine receptor agonist
  40. GC11501 TCN 238 A positive allosteric modulator of mGluR4
  41. GC10175 GW 803430

    GW-3430

     An antagonist of MCH1
  42. GC13346 TQS TQS 是一种 α7 烟碱型乙酰胆碱受体 (nAChR) 正变构调节剂。
  43. GC15367 EMDT oxalate EMDT 草酸盐是一种选择性 5-HT6 激动剂，具有抗抑郁作用。
  44. GC13183 SB 277011A dihydrochloride

    SB-277011A dihydrochloride

     A selective dopamine D3 antagonist
  45. GC12015 Sonepiprazole

    PNU-101387G; U-101387G

     A selective D4 receptor antagonist
  46. GC10051 MDL 100907

    MDL100907; M 100907

     Selective antagonist of the serotonin receptor 5-HT2A
  47. GC12770 LY 2087101 Allosteric potentiator of α7, α4β2 and α4β4 nAChRs
  48. GC12705 Cinnabarinic acid

    朱砂精酸

    An agonist of mGluR4 and active metabolite of 3-hydroxyanthranilic acid
  49. GC14414 CIQ

    (3-氯苯基)[3,4-二氢-6,7-二甲氧基-1-[(4-甲氧基苯氧基)甲基]-2(1H)-异喹啉基]甲酮

     A subunit-selective NMDA receptor potentiator
  50. GC14163 PE 154 PE 154 (Compound 13) 是人乙酰胆碱酯酶 (AChE) 和丁酰胆碱酯酶 (BChE) 的有效荧光抑制剂（IC50s 分别为 280 pM 和 16 nM）。
  51. GC16730 Lisuride maleate

    New Product

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