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Home >> Signaling Pathways >> Neuroscience

Neuroscience(神经科学)

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for  Neuroscience

  1. Cat.No. 产品名称 Information
  2. GC35524 Biperiden

    比哌立登; 碧卜利旦; KL 373

     Biperiden(KL 373)有抗帕金森症活性，是中枢M1胆碱受体阻断剂。
  3. GC35493 Benzoylgomisin O

    苯甲酰戈米辛O

     Benzoylgomisin O 是从 Schisandra rubriflora 中分离的化合物，对 15-LOX、COX-1、COX-2 酶有抑制作用，且具有抗炎活性。
  4. GC35492 Benzamide Derivative 1 Benzamide Derivative 1是来自专利EP0213775A1，化合物18，的苯甲酰胺衍生物。Benzamide Derivative 1可能用于治疗胃肠疾病的研究。
  5. GC35473 Bavisant dihydrochloride hydrate

    JNJ31001074AAC; JNJ31001074 dihydrochloride hydrate

     Bavisant dihydrochloride hydrate (JNJ31001074AAC) 是口服活性人H3 受体拮抗剂。
  6. GC35472 Bavisant dihydrochloride

    JNJ-31001074 dihydrochloride

     Bavisant盐酸盐(JNJ-31001074)是口服活性人H3受体拮抗剂。
  7. GC35471 Bavisant

    JNJ-31001074

     Bavisant (JNJ-31001074)是口服活性人H3受体拮抗剂。
  8. GC35455 BACE1-IN-4 BACE1-IN-4 是一种有效、高度选择性的 BACE1 抑制剂，IC50 值为 3.8 nM，Ki 值为 1.9 nM。抗阿尔滋海默症。
  9. GC35444 Azaphen dihydrochloride monohydrate

    5-甲基-3-(4-甲基-1-哌嗪基)-5H-哒嗪并[3,4-B][1,4]苯并恶嗪二盐酸盐一水合物,Azafen dihydrochloride monohydrate; Pipofezin dihydrochloride monohydrate; Pipofezine dihydrochloride monohydrate; Azaphenonxazine dihydrochloride monohydrate

     Pipofezine(Azafen，Azaphen)是5-羟色胺重吸收抑制剂。
  10. GC35443 Azaphen

    阿扎吩,Azafen; Pipofezin hydrochloride; Pipofezine hydrochloride

     Pipofezine(Azafen,Azaphen)是5-羟色胺重吸收抑制剂。
  11. GC35432 Autocamtide-2-related inhibitory peptide (TFA) A CaMKII inhibitor
  12. GC35428 Atropine sulfate

    硫酸阿托品; 硫酸阿妥品; 硫酸阿托平; 硫酸阿脱品; Tropine tropate sulfate; DL-Hyoscyamine sulfate; Sulfatropinol

     A non-selective muscarinic acetylcholine receptor antagonist
  13. GC35427 Atropine methyl bromide

    甲溴阿托品; Methylatropine bromide

     A muscarinic acetylcholine receptor antagonist
  14. GC35386 Aripiprazole D8

    OPC-14597 D8

     An internal standard for the quantification of aripiprazole
  15. GC35381 Arborine

    山柑子碱

     Arborine 可从 Glycosmis arborea 中分离。Arborine 抑制乙酰胆碱的外周作用并诱导血压下降。
  16. GC35334 Amyloid β Peptide (42-1)(human)

    淀粉Β-蛋白(42-1),Amyloid β Peptide (42-1)(human)

     淀粉样蛋白 β Peptide (42-1)(human) 是淀粉样蛋白 β 的无活性形式；肽 (1-42)。
  17. GC35323 Amisulpride hydrochloride

    氨磺必利盐酸盐; DAN 2163 hydrochloride

     A dopamine D2 and D3 and 5-HT2B, 5-HT7, and 5-HT7A receptor antagonist
  18. GC35303 Alosetron D3 Hydrochloride

    GR-68755C D3

     Alosetron D3 Hydrochloride (GR-68755C D3) 是Alosetron氘代化合物标准品。
  19. GC35302 Alosetron (Hydrochloride(1:X))

    盐酸阿洛司琼,GR 68755 (Hydrochloride(1

     A 5-HT3 receptor antagonist
  20. GC35301 Alosetron ((Z)-2-butenedioate)

    马来酸阿洛司琼; GR 68755 ((Z)-2-butenedioate); GR 68755X ((Z)-2-butenedioate)

     Alosetron (Z)-2-butenedioate (GR 68755 (Z)-2-butenedioate) 是5-HT3受体拮抗剂，可作用于肠易激综合征。
  21. GC35299 Aloeresin D

    芦荟新苷 D

     Aloeresin D 是从芦荟中分离得到的色原酮苷，可抑制 β-分泌酶 (BACE1) 活性，IC50 值为 39 μM。
  22. GC35284 Alimemazine D6

    阿利马嗪D6,Trimeprazine D6

     Alimemazine D6是Alimemazine氘代化合物标准品。
  23. GC35279 Aldicarb sulfone

    涕灭威砜

     A metabolite of aldicarb
  24. GC35272 Ajmalicine

    萝巴新,Raubasine

     A terpenoid indole alkaloid
  25. GC35270 Agomelatine L(+)-Tartaric acid

    阿戈美拉汀 L(+)-酒石酸; S-20098 L(+)-Tartaric acid

     Agomelatine（L(+)-酒石酸）可抗抑郁，是一种去甲肾上腺素-多巴胺抑制解除剂（NDDI），能拮抗5-HT2C受体。
  26. GC35269 Agomelatine hydrochloride

    维度新; S-20098 hydrochloride

     A melatonin receptor agonist and 5-HT2B and 5-HT2C antagonist
  27. GC35256 Adrenomedullin (11-50), rat A truncated form of rat adrenomedullin
  28. GC35252 Adoprazine

    阿哆嗪; SLV313

     Adoprazine是5-HT1A受体的完全激动剂和D2/3受体的拮抗剂。
  29. GC35236 Acetylshikonin

    乙酰紫草素

     Acetylshikonin，来源于紫草根，具有抗癌、抗炎作用。Acetylshikonin 是一种非选择性的细胞色素 P450 抑制剂，对所有 P450 亚型抑制的 IC50 值范围为 1.4-4.0 μM。Acetylshikonin 是一种 AChE 抑制剂，具有很强的抗凋亡活性。
  30. GC35222 ABT-239 ABT-239 是一种新颖的，高效的，非咪唑类的 H3R 拮抗剂，也是 TRPV1 的拮抗剂。
  31. GC35192 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone

    3,4-二氢-7-羟基-2(1H)-喹啉酮,3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

     7-Hydroxy-3,4-dihydrocarbostyril is used as the materials for the organic synthesis intermediates.
  32. GC35027 [Sar9] Substance P [Sar9] Substance P 是一种有效的选择性神经激肽 (NK)-1 受体激动剂。
  33. GC35019 [Nle11]-Substance P [Nle11]-Substance P 是物质 P 类似物，避免了甲硫氨酸氧化问题。
  34. GC35013 [8]-Shogaol

    8-姜烯酚

     [8]-Shogaol，生姜中的一种刺激性酚类化合物，具有抗血小板活性 (IC50=5 μM) 和抑制 COX-2 (IC50=17.5 μM)。[8]-Shogaol 诱导人白血病细胞凋亡。
  35. GC35012 [10]-Shogaol

    10-姜烯酚

     A phenol with diverse biological activities
  36. GC35011 (Z)-Thiothixene

    替沃噻吨

     (Z)-Thiothixene 是 serotonergic receptor 的拮抗剂，来自专利 US 20150141345 A1。
  37. GC35006 (S)-Rasagiline mesylate

    (S)-雷沙吉兰甲磺酸; TVP1022 mesylate; S-PAI mesylate

     (S)-Rasagiline (TVP1022) 甲磺酸盐是S-构型Rasagiline，对MAO-B的活性弱。
  38. GC34998 (S)-(-)-5-Fluorowillardiine hydrochloride

    (5S)-Fluorowillardiine hydrochloride; (S)-5-Fluorowillardiine hydrochloride

     (S)-(-)-5-Fluorowillardiine hydrochloride 是AMPAR高效选择性激动剂。
  39. GC34995 (R,R)-Palonosetron Hydrochloride

    (R,R)-盐酸帕洛诺司琼

     (R,R)-Palonosetron Hydrochloride 是一个有活性的 Palonosetron 对映异构体。
  40. GC34993 (R)-Rivastigmine D6 tartrate

    酒石酸卡巴拉汀 D6

     An internal standard for the quantification of rivastigmine
  41. GC34986 (R)-Baclofen hydrochloride

    (R)-巴氯芬盐酸盐; Arbaclofen hydrochloride; STX 209 hydrochloride

     A GABAB receptor agonist
  42. GC34959 (+)-Sparteine

    (+)-鹰爪豆碱

     A quinolizidine alkaloid
  43. GC34957 (+)-Cevimeline hydrochloride hemihydrate

    (-)-SNI-2011; (-)-AF102B hydrochloride hemihydrate

     (_addition_)-Cevimeline盐酸水合物是mAChR激动剂。
  44. GC34954 (+)-Borneol

    (+)-冰片

     A bicyclic monoterpene with diverse biological activities
  45. GC34949 (-)-Isocorypalmine

    (-)-异延胡索单酚碱,Tetrahydrocolumbamine; (S)-Tetrahydrocolumbamine

     An isoquinoline alkaloid and metabolite of L-THP with diverse biological activities
  46. GC34947 (-)-Corynoxidine

    延胡索乙素N氧化物

    (-)-Corynoxidine 分离自延胡索 Corydalis speciosa，是一种乙酰胆碱酯酶 acetylcholinesterase 抑制剂，IC50 值为 89.0 μM。(-)-Corynoxidine 对金黄色葡萄球菌和耐甲氧西林金黄色葡萄球菌菌株有不同程度的抗菌活性。
  47. GC45263 (+)-D-threo-PDMP (hydrochloride)

    D-PDMP

     An inhibitor of sphingolipid biosynthesis
  48. GC45250 (-)-L-threo-PDMP (hydrochloride) An enhancer of ganglioside biosynthesis
  49. GC45244 (-)-(α)-Kainic Acid (hydrate)

    红藻氨酸

    An L-glutamate analog with neuroexcitatory activities
  50. GC45242 ω-Conotoxin MVIIC (trifluoroacetate salt)

    SNX-230

     An N-, P-, and Q-type calcium channel blocker
  51. GC45241 ω-Conotoxin GVIA (trifluoroacetate salt) ω-Conotoxin GVIA is a peptide originally isolated from the marine mollusk C.

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