Chromatin/Epigenetics(染色质/表观遗传学)

Epigenetics

Epigenetics means above genetics. It determines how much and whether a gene is expressed without changing DNA sequences. Epigenetic regulations include, 1. DNA methylation: the addition of methyl group to DNA, converting cytosine to 5-methylcytosine, mostly at CpG sites; 2. Histone modifications: posttranslational modificationEpigeneticss of histone proteins including acetylation, methylation, ubiquitylation, phosphorylation and sumoylation; 3. miRNAs: non-coding microRNA downregulating gene expression; 4. Prions: infectious proteins viewed as epigenetic agents capable of inducing a phenotype without changing the genome.

Products for Chromatin/Epigenetics

Cat.No. 产品名称 Information
GC43848 Histone H3K27Me2 (23-34) (trifluoroacetate salt)
Lys(Me2)27-Histone H3 (23-34), Histone H3 (23-34) (Lys27me2), KAAR-K(Me2)-SAPATGG
A peptide fragment of histone H3
GC43847 Histone H3K27Me2 (21-44)-GK-biotin (trifluoroacetate salt)
ATKAAR-K(Me2)-SAPATGGVKKPHRYRPG-GK(Biotin), Histone H3 (21-24) (Lys27me2)-GK(Biotin), Lys(Me2)27-Histone H3 (21-44)-GK(Biotin) (trifluoroacetate salt)
A biotinylated peptide fragment of histone H3
GC43846 Histone H3K27Me1 (23-34) (trifluoroacetate salt)
Histone H3 (23-34) (Lys27me1), KAAR-K(Me1)-SAPATGG, Lys(Me1)27-Histone H3 (23-34)
A peptide fragment of histone H3
GC43845 Histone H3K27Me1 (21-44)-GK-biotin (trifluoroacetate salt)
ATKAAR-K(Me1)-SAPATGGVKKPHRYRPG-GK(Biotin), Lys(Me1)27-Histone H3 (21-44)-GK(Biotin), Histone H3 (21-44) (Lys27me1)
A biotinylated peptide fragment of histone H3
GC43844 Histone H3K27Me1 (15-39)-K-biotin (trifluoroacetate salt)
Lys(Me1)27-Histone H3 (15-39)-K(Biotin), Histone H3 (15-39) (Lys27me1), APRKQLATKAAR-K(Me)-SAPATGGVKKPH-K(Biotin)-NH2
A biotinylated peptide fragment of histone H3
GC43843 Histone H3K27Ac (23-34) (human, mouse, rat, bovine) (trifluoroacetate salt)
Histone H3 (23-34) (Lys27ac), KAAR-K(Ac)-SAPATGG, Lys(Ac)27-Histone H3 (23-34)
A peptide fragment of histone H3
GC43842 Histone H3K27Ac (21-44)-GK-biotin amide (trifluoroacetate salt)
ATKAAR-K(Ac)-SAPSTGGVKKPHRYRPGG-K(Biotin)-NH2
A biotinylated peptide fragment of histone H3
GC43841 Histone H3K27Ac (21-43)-GGK-biotin (trifluoroacetate salt)
ATKAAR-K(Ac)-SAPATGGVKKPHRYRPG-GK(Biotin), Lys(Ac)27-Histone H3 (21-43)-GGK(Biotin)
A biotinylated peptide fragment of histone H3
GC43840 Histone H3K14Ac (9-19) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt)
Histone H3 (9-19) (Lys14ac), H3K14Ac, KSTGG-K(Ac)-APRKQ, Lys(Ac)14-Histone H3 (9-19)
A peptide fragment of histone H3
GC43839 Histone H3K14Ac (1-19) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt)
ARTKQTARKSTGG-K(Ac)-APRKQ, Lys(Ac)14-Histone H3 (1-19), Histone H3 (Lys14ac)
A peptide fragment of histone H3
GC43837 Histone H3 Peptide Substrate (1-21)
H3 Peptide
Target substrate for several histone modifying enzymes
GC43835 Histone H3 (5-23) (yeast) (trifluoroacetate salt)
H3p19, QTARKSTGGKAPRKQLASK
A peptide fragment of histone H3
GC43834 Histone H3 (5-23) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt)
QTARKSTGGKAPRKQLATK
A peptide fragment of histone H3
GC43833 Histone H3 (23-34) (human, mouse, rat, bovine) (trifluoroacetate salt)
KAARKSAPATGG
A peptide fragment of histone H3
GC43832 Histone H3 (21-44)-GK-biotin amide (trifluoroacetate salt)
ATKAARKSAPSTGGVKKPHRYRPG-GK(Biotin)-NH2, Histone H3 (21-44)
A biotinylated peptide fragment of histone H3
GC43831 Histone H3 (21-44)-GK-biotin (trifluoroacetate salt)
ATKAARKSAPATGGVKKPHRYRPG-GK(Biotin)
A biotinylated peptide fragment of histone H3
GC43830 Histone H3 (21-44) (Phospho-Ser28) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt)
ATKAARK-pS-APSTGGVKKPHRYRPG, pSer28-Histone H3 (21-44)
A peptide fragment of histone H3
GC43829 Histone H3 (1-20) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt)
ARTKQTARKSTGGKAPRKQL
A peptide fragment of histone H3
GC43828 Histone H3 (1-18)-WC amide (trifluoroacetate salt)
ARTKQTARKSTGGKAPRKWC-NH2
A peptide fragment of histone H3
GC43827 Histone H3 (1-15) (Phospho-Ser10) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt)
ARTKQTARK-pS-TGGKA, pSer10-Histone H3 (1-15), 1-15 H3pS10, H3S10ph (1-15), H31-15S10ph
A peptide fragment of histone H3
GC43826 Histone H2A (1-20) (human, mouse, rat, bovine) (trifluoroacetate salt)
H-Ser-Gly-Arg-Gly-Lys-Gln-Gly-Gly-Lys-Ala-Arg-Ala-Lys-Ala-Lys-Thr-Arg-Ser-Ser-Arg-OH, SGRGKQGGKARAKAKTRSSR
A peptide fragment of histone H2A
GC43806 HC Toxin
玉米圆斑病菌毒素
Potent HDAC inhibitor
GC43794 GSK-J5 (hydrochloride) A negative control compound for GSK-J4
GC43792 GSK-J2 (sodium salt) A negative control compound for GSK-J1
GC43789 GSK199 (hydrochloride) A PAD4 inhibitor
GC43788 GSK121 (trifluoroacetate salt) A PAD4 inhibitor
GC43787 GSK106 (hydrochloride) An inactive control for GSK484 and GSK199
GC43715 Furamidine (hydrochloride)
呋喃脒二盐酸盐,DB75 dihydrochloride; NSC 305831 dihydrochloride
A selective PRMT1 inhibitor and antiprotozoal agent
GC43651 F-Amidine (trifluoroacetate salt) A PAD inhibitor
GC43406 Delphinidin (chloride)
氯化花翠素
Natural vasorelaxant and inhibitor of EGFRs and HATs
GC43354 Cysmethynil
Icmt Inhibitor
An inhibitor of protein prenylation
GC43321 CPTH6 (hydrobromide) A Gcn5 and pCAF HAT inhibitor
GC43320 CPI-268456 A ligand of BRD4
GC43318 coumarin-SAHA
coumarin-Suberoylanilide Hydroxamic Acid
A fluorescent probe for HDAC
GC43275 Citrulline-specific Probe-Rhodamine
Rhodamine Phenylglyoxal, RhPG
A fluorophore that detects protein citrullination
GC43202 CAY10723
AFM30a, AMF30a
A PAD2 inhibitor
GC43201 CAY10722 A SIRT3 inhibitor
GC43200 CAY10721 An inhibitor of SIRT3
GC43192 CAY10685 A “clickable” analog of CPTH2
GC43147 CAY10398
MD 85, PX 089274
A potent, cost-effective histone deacetylase inhibitor
GC42944 BIX01294 (hydrochloride hydrate) An inhibitor of G9a histone methyltransferase
GC42933 Binucleine 2 An inhibitor of Drosophila Aurora B kinase
GC42910 BB-F-Yne A clickable PAD inhibitor
GC42790 Amodiaquine
阿莫地喹,Amodiaquin
A prodrug form of N-desethyl amodiaquine
GC42785 Amifostine (hydrate)
氨磷汀三水合物,WR2721 trihydrate
A broad-spectrum radioprotective thiol
GC42784 AMI-1 (sodium salt)
Arginine N-Methyltransferase Inhibitor-1
A cell permeable inhibitor of PRMTs
GC42562 5-Methyl-2'-deoxycytidine
5-甲基-2'-脱氧胞苷,5-Methyldeoxycytidine
A pyrimidine nucleoside
GC42466 4-pentynoyl-Coenzyme A (trifluoroacetate salt)
Click Tag 4pentynoylCoA
A protein acetylation probe
GC42075 2,4-Pyridinedicarboxylic Acid (hydrate)
2,4-吡啶二羧酸
An inhibitor of 2-oxoglutarate-dependent enzymes
GC41984 1-Alaninechlamydocin An HDAC inhibitor