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Sphingosine Kinase-2(鞘氨醇激酶-2)

Sphk2 (sphingosine Kinase-2) It is one of the two mammalian isoforms of Sphk. It catalyzes the phosphorylation of sphingosine to sphingosine 1-phoshate. It is associated with breast and colon cancer.

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  2. GC10154 ABC294640 ABC294640 (ABC294640) 是一种选择性的、竞争性的鞘氨醇激酶 2 (SK2) 抑制剂,Ki 为 9.8 μM.

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