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Home >> Signaling Pathways >> PI3K/Akt/mTOR Signaling

PI3K/Akt/mTOR Signaling(PI3K/Akt/mTOR 信号传导)

  1. Cat.No. 产品名称 Information
  2. GC16960 4,5,6,7-Tetrabromobenzimidazole A selective inhibitor of CK2
  3. GC14181 TBCA An inhibitor of casein kinase 2
  4. GC12416 INK1117

    A selective inhibitor of PI3Kα
  5. GC13176 CP21R7 A GSK3β inhibitor used to differentiate stem cells
  6. GC12889 PX 866 An inhibitor of PI3K
  7. GC10436 VPS34-IN1 A potent and selective inhibitor of Vps34
  8. GC11248 AZD8835 An inhibitor of PI3Kα and PI3Kδ
  9. GC15679 GSK2292767 A potent and selective inhibitor of PI3Kδ
  10. GC13648 CC-223 A potent, selective inhibitor of mTOR
  11. GC16039 LJH685 An inhibitor of RSKs
  12. GC14679 PIK-III A selective inhibitor of Vps34
  13. GC16654 CC-115 A dual inhibitor of mTOR and DNA-PK
  14. GC14371 LY3023414 LY3023414 (LY3023414) potently and selectively inhibits class I PI3K isoforms, DNA-PK, and mTORC1/2 with IC50s of 6.07 nM, 77.6 nM, 38 nM, 23.8 nM, 4.24 nM and 165 nM for PI3Kα, PI3Kβ, PI3Kδ , PI3Kγ, DNA-PK 和 mTOR, 分别。 LY3023414 在低纳摩尔浓度下有效抑制 mTORC1/2。
  15. GC16601 LJI308 An inhibitor of RSKs
  16. GC11724 GSK621 An AMPK activator
  17. GC13913 AMG319 Potent, selective PI3Kδ inhibitor
  18. GC12576 AZD8186 A PI3Kβ/δ inhibitor
  19. GC12375 PF-4989216 An orally bioavailable PI3K inhibitor
  20. GC13790 MHY1485

    An mTOR activator
  21. GC17500 SU6656 Inhibitor of Src kinases
  22. GC15615 BX517(PDK1 inhibitor2) An inhibitor of PDK1
  23. GC10860 Acalisib (GS-9820) An inhibitor of p110δ
  24. GC12089 LY2584702 A p70S6K inhibitor
  25. GC17338 GNE-317 A dual PI3Kα and mTOR inhibitor
  26. GC11325 CX-4945 sodium salt A potent, orally bioavailable CK2 inhibitor
  27. GC10752 Bikinin An inhibitor of Arabidopsis shaggy-related kinases
  28. GC11471 SAR405 A selective inhibitor of Vps34
  29. GC12162 ZLN024 hydrochloride An allosteric activator of AMPK
  30. GC16475 Afuresertib A pan-Akt inhibitor
  31. GC16617 IM-12 A GSK3β inhibitor
  32. GC10340 GNE-477 A dual PI3K and mTOR inhibitor
  33. GC15423 GNE-493 A dual inhibitor of PI3K and mTOR
  34. GC13185 HTH-01-015 A selective NUAK1 inhibitor
  35. GC16713 HS-173 A PI3K inhibitor
  36. GC10386 PI 828

    A PI3K inhibitor
  37. GC13503 iMDK iMDK 是一种有效的 PI3K 抑制剂，可抑制生长因子 MDK（也称为中期因子或 MK）。 iMDK 与 MEK 抑制剂协同抑制非小细胞肺癌 (NSCLC)，而不会伤害正常细胞和小鼠。
  38. GC15642 CHIR 99021 trihydrochloride A selective GSK3 inhibitor
  39. GC11645 SC 79

    An Akt activator
  40. GC11985 SC 66 A dual inhibitor of Akt
  41. GC14233 BIO-acetoxime A potent, selective inhibitor of GSK3α/β
  42. GC12324 RSVA 405 RSVA 405 是一种有效的口服活性 AMPK 激活剂，EC50 为 1 μM。
  43. GC10336 A 1070722 A GSK3β inhibitor
  44. GC11690 PIT 1 An inhibitor of PIP3/protein binding
  45. GC13920 PS 48 PDK1激活剂
  46. GC17204 PT 1 An activator of AMPK
  47. GC17963 CHPG Sodium salt CHPG 钠盐是一种选择性 mGluR5 激动剂，可通过 BV2 小胶质细胞中的 TSG-6/NF-κB 通路减弱 SO2 诱导的氧化应激和炎症。
  48. GC10195 Z-Guggulsterone A farnesoid X receptor antagonist
  49. GC10812 Compound 401 A dual inhibitor of mTOR and DNA-PK
  50. GC17984 FPA 124 A cell-permeable Akt inhibitor
  51. GC13006 10-DEBC hydrochloride A selective inhibitor of Akt

Items 351 to 400 of 578 total

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