DNA-PK(DNA依赖蛋白激酶)
DNA-PK is a serine/threonine kinase and acts a molecular sensor for DNA damage. It is involved in NHEJ (non-homologous end joining) for DSB (DNA double strand break) repair and V(D)J recombination.
- Cat.No. 产品名称 Information
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GC65249
STL127705
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GC64938
AZD-7648
An inhibitor of DNA-PK
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GC64818
AMA-37
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GC63763
BAY-8400
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GC34749
Rac-Nedisertib
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GC34444
(R)-Nedisertib
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GC34121
CC-115 hydrochloride
A dual inhibitor of mTOR and DNA-PK
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GC33325
VX-984 (M9831)
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GC32718
M3814 (nedisertib)
Nedisertib (M3814, Peposertib, MSC2490484A) is an orally bioavailable, highly potent and selective inhibitor of DNA activated protein kinase (DNA-PK) with IC50 of < 3 nM.
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GC19390
YU238259
An inhibitor of homology-dependent DNA repair
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GC19328
SF2523
A dual inhibitor of PI3K and BRD4
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GC19227
LTURM34
An inhibitor of DNA-PK
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GC16654
CC-115
A dual inhibitor of mTOR and DNA-PK
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GC14371
LY3023414
LY3023414 (LY3023414) potently and selectively inhibits class I PI3K isoforms, DNA-PK, and mTORC1/2 with IC50s of 6.07 nM, 77.6 nM, 38 nM, 23.8 nM, 4.24 nM and 165 nM for PI3Kα, PI3Kβ, PI3Kδ , PI3Kγ, DNA-PK 和 mTOR, 分别。 LY3023414 在低纳摩尔浓度下有效抑制 mTORC1/2。
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GC10812
Compound 401
A dual inhibitor of mTOR and DNA-PK
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GC13858
Torin 2
Selective inhibitor of mTOR
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GC12332
NU 7026
Inhibitor of DNA-dependent protein kinase
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GC10196
ETP-46464
An ATR inhibitor
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GC11251
NU7441 (KU-57788)
A selective DNA-PK inhibitor
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GC14346
KU-0060648
A dual inhibitor of DNA-PK and PI3K
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GC16904
PIK-75
A selective p110α inhibitor
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GC17199
PIK-90
Potent, cell permeable PI3K inhibitor
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GC11165
PI-103
A potent, cell-permeable PI3-kinase inhibitor
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GC15485
LY 294002
A selective PI3K inhibitor
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GC16379
PI-103 Hydrochloride
A potent, cell-permeable PI3K inhibitor
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GC11175
Daun02
Daun02 是拓扑异构酶抑制剂柔红霉素的前药。