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Home >> Signaling Pathways >> Stem Cell

Stem Cell(干细胞)

  1. Cat.No. 产品名称 Information
  2. GC13028 SB 415286 A selective inhibitor of GSK-3
  3. GC10463 SB 216763

    SB 216763 stands out as a powerful, selective, and ATP-competitive inhibitor of GSK-3, effectively targeting both GSK-3α and GSK-3β with an impressive IC50 of 34.3 nM[1-3].
  4. GC15064 Purmorphamine Purmorphamine is the first small molecule agonist developed for Smoothened protein.
  5. GC17043 StemRegenin 1 (SR1) Antagonizes hematopoietic stem cell differentiation
  6. GC16893 ICG 001 An inhibitor of β-catenin/CBP interactions
  7. GC14572 KY 02111 Induces stem cell differentiation
  8. GC11674 WIKI4 A potent TNKS1/2 inhibitor
  9. GC12869 JW 55 A TNKS1/2 inhibitor
  10. GC16584 TCS 21311 A JAK3 inhibitor
  11. GC10649 TTP 22 A CK2 inhibitor
  12. GC14037 Triptonide A diterpenoid with diverse biological activities
  13. GC12181 TBB An inhibitor of CK2
  14. GC18107 Salinomycin sodium salt A selective cancer stem cell inhibitor
  15. GC14882 Salinomycin A selective cancer stem cell inhibitor
  16. GC10556 PF-670462 An inhibitor of the CK1 isoforms CK1ε and CK1δ
  17. GC17187 LY2090314 A potent and selective inhibitor of GSK3
  18. GC14169 LDE225 Diphosphate A Smo antagonist
  19. GC16454 IWP-2 IWP-2 是Wnt信号通路的抑制剂,IC50值为 27 nM。IWP-2还是一种具有ATP竞争能力的Casein Kinase 1δ(CK1δ) 抑制剂,IC50值为40 nM。
  20. GC12951 HhAntag A hedgehog pathway inhibitor
  21. GC17534 GSK343 A selective, cell-permeable EZH2 inhibitor
  22. GC15783 GSK126

    A selective EZH2 inhibitor
  23. GC16789 GANT 58 An inhibitor of Gli transcription
  24. GC12134 FH535 An inhibitor of β-catenin signaling
  25. GC16044 Emodin Natural CK2 inhibitor and ER agonist
  26. GC17837 DMAT A cell-permeable inhibitor of CK2
  27. GC13202 D4476 Inhibitor of CK1 and ALK5
  28. GC13628 BMS-833923 An orally bioavailable Smo inhibitor
  29. GC15425 AR-A014418 A selective inhibitor of GSK3β
  30. GC17107 PluriSIn #1 (NSC 14613) A selective inhibitor of stearoyl-CoA desaturase
  31. GC12653 LY3039478 A Notch inhibitor
  32. GC15794 Valproic acid sodium salt (Sodium valproate) A class I HDAC inhibitor
  33. GC13878 EPZ005687 A potent, selective inhibitor of EZH2
  34. GC13673 BMS-708163 (Avagacestat) A potent inhibitor of γ-secretase
  35. GC12191 LY-411575 A γ-secretase inhibitor
  36. GC17671 YO-01027 (Dibenzazepine, DBZ) An inhibitor of γ-secretase
  37. GC16197 RO4929097

    An inhibitor of γ-secretase
  38. GC10493 GDC-0449 (Vismodegib) GDC-0449 (Vismodegib) (GDC-0449) 是一种具有口服活性的hedgehog 通路抑制剂，IC50 为3 nM。 GDC-0449 (Vismodegib) 还抑制 P-gp、ABCG2，IC50 值分别为 3.0 μM 和 1.4 μM。
  39. GC16702 CHIR-99021 (CT99021)

    一种选择性的GSK3抑制剂
  40. GN10797 Tangeretin Polymethoxylated flavone
  41. GC12096 Semagacestat (LY450139) A pan γ-secretase inhibitor
  42. GN10017 Wogonin A flavonoid with anti-inflammatory and antitumor activities
  43. GC17907 3-Deazaneplanocin A (DZNep) hydrochloride An inhibitor of the lysine methyltransferase EZH2
  44. GC13145 3-Deazaneplanocin,DZNep

    An inhibitor of lysine methyltransferase EZH2

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