Stem Cell(干细胞)
- CK1(5)
- EZH2(10)
- GSK-3(63)
- HSC(6)
- iPSC(6)
- Hedgehog(37)
- Notch(33)
- Smoothened(34)
- Wnt/β-catenin(117)
- Hippo Signaling(5)
- Cancer stem cell(23)
- MST1/2(1)
- ESC(1)
- Oct3/4(5)
- Porcupine(6)
- YAP(22)
- Casein Kinase(40)
- Cat.No. 产品名称 Information
- GC13028 SB 415286 A selective inhibitor of GSK-3
-
GC10463
SB 216763
SB 216763 stands out as a powerful, selective, and ATP-competitive inhibitor of GSK-3, effectively targeting both GSK-3α and GSK-3β with an impressive IC50 of 34.3 nM[1-3].
- GC15064 Purmorphamine Purmorphamine is the first small molecule agonist developed for Smoothened protein.
- GC17043 StemRegenin 1 (SR1) Antagonizes hematopoietic stem cell differentiation
- GC16893 ICG 001 An inhibitor of β-catenin/CBP interactions
- GC14572 KY 02111 Induces stem cell differentiation
- GC11674 WIKI4 A potent TNKS1/2 inhibitor
- GC12869 JW 55 A TNKS1/2 inhibitor
- GC16584 TCS 21311 A JAK3 inhibitor
- GC10649 TTP 22 A CK2 inhibitor
- GC14037 Triptonide A diterpenoid with diverse biological activities
- GC12181 TBB An inhibitor of CK2
- GC18107 Salinomycin sodium salt A selective cancer stem cell inhibitor
- GC14882 Salinomycin A selective cancer stem cell inhibitor
- GC10556 PF-670462 An inhibitor of the CK1 isoforms CK1ε and CK1δ
- GC17187 LY2090314 A potent and selective inhibitor of GSK3
- GC14169 LDE225 Diphosphate A Smo antagonist
- GC16454 IWP-2 IWP-2 是Wnt信号通路的抑制剂,IC50值为 27 nM。IWP-2还是一种具有ATP竞争能力的Casein Kinase 1δ(CK1δ) 抑制剂,IC50值为40 nM。
- GC12951 HhAntag A hedgehog pathway inhibitor
- GC17534 GSK343 A selective, cell-permeable EZH2 inhibitor
-
GC15783
GSK126
A selective EZH2 inhibitor
- GC16789 GANT 58 An inhibitor of Gli transcription
- GC12134 FH535 An inhibitor of β-catenin signaling
- GC16044 Emodin Natural CK2 inhibitor and ER agonist
- GC17837 DMAT A cell-permeable inhibitor of CK2
- GC13202 D4476 Inhibitor of CK1 and ALK5
- GC13628 BMS-833923 An orally bioavailable Smo inhibitor
- GC15425 AR-A014418 A selective inhibitor of GSK3β
- GC17107 PluriSIn #1 (NSC 14613) A selective inhibitor of stearoyl-CoA desaturase
- GC12653 LY3039478 A Notch inhibitor
- GC15794 Valproic acid sodium salt (Sodium valproate) A class I HDAC inhibitor
- GC13878 EPZ005687 A potent, selective inhibitor of EZH2
- GC13673 BMS-708163 (Avagacestat) A potent inhibitor of γ-secretase
- GC12191 LY-411575 A γ-secretase inhibitor
- GC17671 YO-01027 (Dibenzazepine, DBZ) An inhibitor of γ-secretase
-
GC16197
RO4929097
An inhibitor of γ-secretase
- GC10493 GDC-0449 (Vismodegib) GDC-0449 (Vismodegib) (GDC-0449) 是一种具有口服活性的hedgehog 通路抑制剂,IC50 为3 nM。 GDC-0449 (Vismodegib) 还抑制 P-gp、ABCG2,IC50 值分别为 3.0 μM 和 1.4 μM。
-
GC16702
CHIR-99021 (CT99021)
一种选择性的GSK3抑制剂
- GN10797 Tangeretin Polymethoxylated flavone
- GC12096 Semagacestat (LY450139) A pan γ-secretase inhibitor
- GN10017 Wogonin A flavonoid with anti-inflammatory and antitumor activities
- GC17907 3-Deazaneplanocin A (DZNep) hydrochloride An inhibitor of the lysine methyltransferase EZH2
-
GC13145
3-Deazaneplanocin,DZNep
An inhibitor of lysine methyltransferase EZH2