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Home >> Signaling Pathways >> Stem Cell

Stem Cell(干细胞)

  1. Cat.No. 产品名称 Information
  2. GC15422 20(S)-Hydroxycholesterol An allosteric Smo agonist
  3. GC15284 U 18666A

    U18666A抑制3β羟基甾醇-Δ（24）还原酶 （DHCR24）活性，阻止胆固醇从晚期核内体和溶酶体外流。
  4. GC14182 Kenpaullone A inhibitor of cyclin-dependent kinase and GSK3β
  5. GC16640 iCRT 14 An inhibitor of β-catenin-responsive transcription
  6. GC11484 CPI-169 S-enantiomer EZH2 inhibitor
  7. GC12146 CPI-169 R-enantiomer EZH2 inhibitor
  8. GC16599 CPI-169 A selective EZH2 inhibitor
  9. GC13907 1-Azakenpaullone A potent inhibitor of GSK3β
  10. GC11115 Pamidronate An FPP synthase inhibitor that inhibits bone resorption
  11. GC10151 OAC1 An Oct4-activating compound
  12. GC11775 Nefopam HCl Nefopam HCl (Fenazoxine hydrochloride) 是一种中枢作用但非阿片类镇痛药，用于缓解中度至重度疼痛。
  13. GC10950 IWR-1-endo

    Inhibitor of Wnt response
  14. GC14896 Halcinonide A synthetic glucocorticoid
  15. GC14987 GSK-3 Inhibitor IX (BIO) A potent, selective, and reversible GSK3 inhibitor
  16. GC13655 LDE225 (NVP-LDE225,Erismodegib) LDE225 (NVP-LDE225,Erismodegib) (Erismodegib) 是一种有效的选择性 Smo 拮抗剂，在结合试验中对小鼠和人 Smo 的 IC50 分别为 1.3 nM 和 2.5 nM。
  17. GC17466 LH846 A selective inhibitor of CK1δ
  18. GC14756 EI1 A selective inhibitor of EZH2
  19. GC14465 Tideglusib A neuroactive thiadiazolidinone
  20. GC16568 AZD1080 A potent inhibitor of GSK3α and GSK3β
  21. GC14840 TDZD-8 A selective inhibitor of GSK3β
  22. GC17868 TWS119 A GSK3β inhibitor
  23. GC11424 Valproic acid A class I HDAC inhibitor
  24. GC17690 Cromolyn sodium A mast cell stabilizer
  25. GC16230 PF-04449913 A Smo antagonist
  26. GC12392 LGK-974 A potent, bioavailable inhibitor of PORCN
  27. GC17708 IWP-L6 A potent inhibitor of Porcupine
  28. GC16701 SKI II An SPHK1 inhibitor
  29. GC14736 AZD2858 A GSK3β inhibitor
  30. GC10211 FLI-06 A Notch inhibitor
  31. GC13658 Wnt-C59 A potent Porcupine inhibitor
  32. GC15889 SANT-1 An antagonist of Smoothened
  33. GC12429 AY 9944 dihydrochloride A cholesterol synthesis inhibitor
  34. GC14715 AZ 12080282 dihydrochloride 刺猬抑制剂
  35. GC11111 Jervine An inhibitor of the hedgehog signaling pathway
  36. GC11476 Ciliobrevin A A hedgehog pathway inhibitor
  37. GC11045 HPI 1 A Hedgehog pathway inhibitor
  38. GC11193 SANT-2 A Smoothened receptor antagonist
  39. GC15256 JK 184 An inhibitor of downstream hedgehog signaling
  40. GC15683 LY2940680 A Smo antagonist
  41. GC11548 Tankyrase Inhibitors (TNKS) 49 Tankyrase inhibitor
  42. GC15041 Tankyrase Inhibitors (TNKS) 22 Tankyrase inhibitor
  43. GC17153 CHIR-99021 (CT99021) HCl A selective GSK3 inhibitor
  44. GC12176 CHIR-98014 A reversible, cell-permeable inhibitor of GSK3
  45. GC13280 PF-5274857 PF-5274857 是一种有效的、选择性的、具有口服活性的脑渗透性 Smo 拮抗剂，IC50 为 5.8 nM，Ki 为 4.6 nM。 PF-5274857 具有研究肿瘤类型的潜力，包括由激活的 Hh 通路驱动的脑肿瘤和脑转移。
  46. GC13441 Cyclopamine An inhibitor of hedgehog signaling
  47. GC13037 CX-4945 (Silmitasertib) A potent, orally bioavailable CK2 inhibitor
  48. GC14482 Verteporfin

    A photosensitizer
  49. GC10359 GANT61 Antagonist of Gli transcription factors, involved in Hedgehog signaling
  50. GC12781 XAV-939

    A TNKS inhibitor
  51. GC15548 Ellagic acid Polyphenolic antioxidant

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