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Home >> Signaling Pathways >> DNA Damage/DNA Repair

DNA Damage/DNA Repair(DNA损伤/DNA修复)

Cat.No. 产品名称 Information
GC12201 HI TOPK 032
TOPK抑制剂(HI-TOPK-032)
An inhibitor of TOPK, Chk1, and MEK1 kinases
GC11774 KH CB19 KH CB19 是一种有效的 CLK（cdc2 样激酶）抑制剂（CLK1 IC50\u003d19.7 nM；CLK3 IC50\u003d530 nM）。
GC14899 AMG 548 An inhibitor of p38α MAPK
GC17418 AbK
H-L-Photo-lysine
AbK (H-L-Photo-lysine) 是一种含有二氮丙啶的赖氨酸氨基酸，是一种光交联剂。
GC15511 LIMKi 3
LIMKi 3
An inhibitor of LIMK1 and LIMK2
GC11040 Borrelidin
疏螺旋体素,Treponemycin
An antiangiogenic antibiotic
GC12092 TMPyP4 tosylate
TMPYP[=Α,Β,Γ,Δ-四(1-甲基吡啶嗡-4-基)卟吩对甲苯磺酸盐][铜和镁用超高灵敏分光光度试剂][用于以高效液相色谱金属同时测定],TMP 1363
A telomerase inhibitor
GC16384 Puromycin dihydrochloride
嘌呤霉素; CL13900 dihydrochloride
Puromycin二盐酸盐是由革兰氏阳性放线菌Streptomyces alboniger通过一系列酶反应产生的。
GC15305 Ellipticine
椭圆玫瑰树碱,NSC 71795
Ellipticine (NSC 71795) 是一种有效的抗肿瘤剂；抑制 DNA 拓扑异构酶 II 的活性。
GC13002 Thiostrepton
硫链丝菌素
An inhibitor of FoxM1
GC14182 Kenpaullone
克莱拉尼,9-Bromopaullone; NSC-664704
A inhibitor of cyclin-dependent kinase and GSK3β
GC12642 THZ1 Hydrochloride A covalent Cdk7 inhibitor
GC14851 Vidofludimus
维多氟拉迪莫,4sc-101; SC12267
An immunosuppressive drug that inhibits DHODH
GC12667 4SC-202
4SC-202(盐的形式),4SC-202
An HDAC1-3 and KDM1A inhibitor
GC16158 Thio-TEPA
三亚乙基硫代磷酰胺
An alkylating agent with anticancer activity
GC12908 Chlorambucil
苯丁酸氮芥,CB-1348; WR-139013
A DNA alkylating agent
GC14162 ML167
5-[4-[[(5-甲基-2-呋喃基)甲基]氨基]-6-喹唑啉基]-2-呋喃甲醇,CID44968231; NCGC00188654
A selective Clk4 inhibitor
GC13764 Nexturastat A A potent, cell-permeable HDAC6 inhibitor
GC13104 4E1RCat
eIF4E/eIF4G Interaction Inhibitor II
An eIF4F inhibitor
GC10468 4EGI-1
eIF4E/eIF4G Interaction Inhibitor
An inhibitor of mRNA translation
GC11940 5-BrdU
5-溴脱氧尿嘧啶核苷; BrdU; 5-Bromo-2'-deoxyuridine; BUdR
5-溴-2’-脱氧尿苷（5-BrdU，5-bromo-2-deoxundine5-BrdU）是一种合成的胸苷溴化类似物，通常用于测定DNA合成和标记分裂细胞。
GC10356 DUBs-IN-3
9-[(2-丙烯-1-氧基)亚氨基]-9H-茚并[1,2-B]吡嗪-2,3-二甲腈
DUBs-IN-3 是一种有效的去泛素酶 (USP) 酶抑制剂，从参考化合物 22c 中提取，对 USP8 的 IC50 为 0.56 μM。
GC17125 DUBs-IN-2
9-乙氧基亚氨基-9H-茚并[1,2-B]吡嗪-2,3-二甲腈
DUBs-IN-2 是一种有效的去泛素酶抑制剂，IC50 为 0.28 μM for USP8。
GC15793 Carmustine
卡莫司汀
A DNA alkylating agent
GC12503 Pixantrone
匹杉琼; BBR 2778 free base
A DNA topoisomerase II inhibitor
GC10840 THZ1 A covalent Cdk7 inhibitor
GC14066 Procaine
普鲁卡因
An Analytical Reference Standard
GC16843 Hydroxyurea
羟基脲; Hydroxycarbamide
An antineoplastic agent
GC13742 Uridine
尿苷; β-Uridine
A pyrimidine nucleoside
GC11825 Adenine HCl
腺嘌呤盐酸盐; 6-Aminopurine hydrochloride; Vitamin B4 hydrochloride
Adenine HCl (6-Aminopurine hydrochloride) 是一种嘌呤，是 DNA 核酸中的四种核碱基之一。盐酸腺嘌呤充当 DNA 和 RNA 的化学成分。腺嘌呤 HCl 在涉及细胞呼吸、ATP 和辅因子（NAD 和 FAD）的形式以及蛋白质合成的生物化学中也发挥着重要作用。
GC15857 Sodium butyrate
丁酸钠
A short-chain fatty acid and HDAC inhibitor
GC17082 Pirarubicin
吡柔比星; THP
An anthracycline antitumor antibiotic
GC17750 Raltitrexed
雷替曲塞; ZD1694; D1694; ICI-D1694
An inhibitor of thymidylate synthase
GC16680 Levoleucovorin Calcium
左亚叶酸钙; Calcium levofolinate; CL307782
A reduced folic acid
GC11698 Valaciclovir HCl
盐酸伐昔洛韦; Valaciclovir hydrochloride
A prodrug of acyclovir
GC11793 Procarbazine HCl
盐酸甲基苄肼
A DNA methylating agent
GC17278 Adenine sulfate
硫酸腺嘌呤; 6-Aminopurine hemisulfate; Vitamin B4 hemisulfate
A purine base
GC10137 Trimethoprim
甲氧苄啶
An antibiotic
GC15786 Nedaplatin
奈达铂,NSC 375101D
An anticancer agent
GC14363 Mitoxantrone HCl
米托蒽醌二盐酸盐; Mitozantrone dihydrochloride; NSC 301739 dihydrochloride
An inhibitor of DNA topoisomerase IIα and HIV-1 integrase
GC14885 Foscarnet Sodium
膦甲酸钠,Trisodium phosphonoformate; Phosphonoformic acid trisodium salt
Foscarnet sodium (Trisodium phosphonoformate) 是一种病毒 DNA 聚合酶活性抑制剂，可导致病毒复制的可逆抑制。
GC16455 Flumequine
氟甲喹; R-802
A fluoroquinolone antibiotic
GC15410 Bufexamac
丁苯羟酸; Bufexamic acid
An NSAID and a class IIb HDAC inhibitor
GC17683 Brefeldin A
布雷非德菌素 A; BFA; Cyanein; Decumbin
Brefeldin A（BFA）是一种真菌大环内酯，能够有效、可逆地抑制内质网和高尔基体之间的蛋白质运输和囊泡形成。
GC14987 GSK-3 Inhibitor IX (BIO)
(2'Z,3'E)-6-溴靛玉红-3'-肟,GSK-3 Inhibitor IX
A potent, selective, and reversible GSK3 inhibitor
GC11843 Azaguanine-8
8-氮鸟嘌呤; 8-AG
Azaguanine-8 是一种嘌呤类似物，具有抗肿瘤活性。 Azaguanine-8 起抗代谢物的作用，很容易与核糖核酸结合，干扰正常的生物合成途径，从而抑制细胞生长。
GC14493 4μ8C
4u8C
4μ8C（7-Hydroxy-4-methyl-2-oxo-2H-1-benzopyran8-carboxaldehyde）是肌醇需求酶1α（IRE1α）RNAse的小分子抑制剂。
GC11528 Orotic acid
乳清酸; 6-Carboxyuracil; Vitamin B13
乳清酸 (6-Carboxyuracil) 是嘧啶核苷酸和 RNA 生物合成的前体，从线粒体二氢乳清酸脱氢酶 (DHODH) 中释放出来，通过细胞质 UMP 合酶转化为 UMP。
GC10082 Vidarabine
阿糖腺苷; Ara-A; Adenine Arabinoside; 9-β-D-Arabinofuranosyladenine
An antiviral nucleoside analog
GC15033 Azathioprine
硫唑嘌呤; BW 57-322
An immunosuppressive purine analog