DNA Alkylating(DNA烷基化)

DNA alkylating is the transfer of alkyl groups to particular bases, resulting in alkylation products such as O2‐alkylthymine and O6‐methylguanine that lead to DNA mutations.

Products for DNA Alkylating

Cat.No. 产品名称 Information
GC91297 Cholesterol-Doxorubicin
Chol-DOX

一种阿霉素的前药形式。
GC90657 COMC
2-Crotonyloxymethyl-2-cyclohexenone

一种抗癌药物。
GC90549 5-Aminoimidazole-4-carboxamide (hydrate)
AIC

一种合成前体
GC52129 3-Amino-5-hydroxybenzoic Acid
3-氨基-5-羟基苯甲酸
A biosynthetic precursor to ansamycin antibiotics
GC52076 Temozolomide Acid
3,4-二氢-3-甲基-4-氧代咪唑并[5,1-D]-1,2,3,5-四嗪-8-甲酰胺酸
An active metabolite of temozolomide
GC49470 1-Ethyl-1-nitrosourea (hydrate)
ENU, Ethylnitrosourea, N-Ethyl-N-nitrosourea, N-Nitroso-N-ethylurea
A DNA alkylating agent
GC47167 Dacarbazine-d6
达卡巴嗪-D6,Imidazole Carboxamide-d6
An internal standard for the quantification of dacarbazine
GC47078 Chlorambucil-d8
CB-1348-d8; WR-139013-d8
苯丁酸氮芥 (CB-1348-d8) 是氘标记的苯丁酸氮芥。苯丁酸氮芥 (CB-1348) 是一种具有口服活性的抗肿瘤剂，是一种属于氮芥类的双功能烷化剂。苯丁酸氮芥可用于淋巴细胞白血病、卵巢癌和乳腺癌以及霍奇金病的研究。
GC46914 Bendamustine-d4 (hydrochloride)
盐酸苯达莫司汀 d4 (盐酸盐)
A neuropeptide with diverse biological activities
GC44348 N-desmethyl Bendamustine
盐酸苯达莫司汀乙酯水解杂质
An active metabolite of bendamustine
GC44251 MTIC
替莫唑胺代谢物- MTIC
A DNA alkylating agent
GC44243 Monohydroxy Melphalan (hydrochloride)
Hydroxymelphalan
A DNA alkylating agent
GC41384 K-TMZ A DNA alkylating agent
GC18100 Illudin S
隐陡头菌素S
A DNA alkylating agent
GC15043 Trioxsalen
三甲沙林; Trisoralen; Trioxysalen; TMP
A UV-activated DNA crosslinking probe
GC16158 Thio-TEPA
三亚乙基硫代磷酰胺
An alkylating agent with anticancer activity
GC15793 Carmustine
卡莫司汀
A DNA alkylating agent
GC13667 Temozolomide
替莫唑胺; NSC 362856; CCRG 81045; TMZ
替莫唑胺是一种口服活性烷化剂，可诱导 DNA 中 O6-甲基鸟嘌呤的形成，其在随后的 DNA 复制周期中与胸腺嘧啶错配，从而激活细胞凋亡途径，替莫唑胺可穿过血脑屏障并适用于恶性神经胶质瘤和转移性黑色素瘤。
GC17865 Lomustine
洛莫司汀; CCNU; NSC 79037
A DNA alkylating agent
GC13671 Busulfan
白消安
An alkylating antineoplastic agent
GC14564 Altretamine
六甲蜜胺; ENT-50852; RB-1515; WR-95704
An antineoplastic agent and GPX4 inhibitor
GC14762 Palifosfamide
帕利伐米,Isophosphoramide mustard;IPM;ZIO-201
An active metabolite of ifosfamide