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Home >> Signaling Pathways >> Microbiology & Virology

Microbiology & Virology(微生物学 & 病毒学)

Virology

A virus is a small infectious agent that replicates inside living cells. Viruses cause many human diseases from small illnesses, like influenza, to more deadly diseases, like hepatitis B and HIV. Our body’s immune system defends against viral infection by generating specific antibodies to bind to and neutralize viral particles and by cell mediated immunity that destroys infected host cells. read more

Products for  Microbiology & Virology

  1. Cat.No. 产品名称 Information
  2. GC39497 ML188 ML188 is a non-covalent SARS-CoV 3CLpro inhibitor with IC50 of 1.5 μM. ML188 has antiviral activity.
  3. GC39478 Antitrypanosomal agent 1

    1-(3,4-二氯苯基)-3-(二甲基氨基)丙-1-酮盐酸盐

     Antitrypanosomal agent 1 是一种有效的，选择性锥虫硫磷还原酶 (trypanothione reductase) 抑制剂，IC50 为 3.3 μM。Antitrypanosomal agent 1 抑制谷胱甘肽还原酶 (glutathione reductase)，IC50 为 64.8 μM；抑制布氏锥虫，EC50 为 1 μM。Antitrypanosomal agent 1 具有抗锥虫活性。
  4. GC39464 α-Cyclodextrin

    α-环糊精

     α-Cyclodextrin 是一个多功能的，可作为纤维原料销售的可溶性膳食纤维。
  5. GC39448 Surfactin C1

    表面活性素

     A lipopeptide biosurfactant
  6. GC39429 Rabeprazole Sulfide

    2-[[[4-(3-甲氧基丙氧基)-3-甲基吡啶-2-基]甲基]硫代]-1H-苯并咪唑

     An active metabolite of rabeprazole
  7. GC39418 p-Anisic acid

    对甲氧基苯甲酸,4-Methoxybenzoic acid; Draconic acid

     p-Anisic acid (4-Methoxybenzoic acid) 是anisic acid 的一个异构体，具有抗菌和防腐活性。
  8. GC39409 Neticonazole hydrochloride

    盐酸奈替康唑

     Neticonazole is an imidazole antifungal for the treatment of fungal skin infections.
  9. GC39408 Neticonazole

    奈康唑

     Neticonazole (SS717) is a selecvie inhibitor of exosome biogenesis and secretion. Neticonazole exhibits Neticonazole antifungal and antitumor activity.
  10. GC39396 LolCDE-IN-1 LolCDE-IN-1 是一种 LolCDE 复合物的抑制剂，具有抗菌活性。
  11. GC39374 DHODH-IN-5 DHODH-IN-5 是一种有效的人二氢硼酸脱氢酶 (DHODH) 抑制剂，人重组 DHODH 的pIC50 为 7.8。DHODH-IN-5 抑制麻疹病毒复制，pMIC50 为 8.8。
  12. GC39373 Desmethyl ferroquine

    SSR97213

     Desmethyl ferroquine (SSR97213) 是 Ferroquine 的主要活性代谢产物。Ferroquine 是一种抗疟剂。Desmethyl ferroquine 显著抑制对 Chloroquine 敏感的和耐 Chloroquine 的恶性疟原虫菌株 P. falciparum。
  13. GC39372 Desethyl chloroquine diphosphate

    脱乙基氯喹二磷酸盐

     Desethyl chloroquine diphosphate 是 Chloroquine 的主要去乙基代谢产物。Chloroquine 是一种自噬和 toll-like receptors (TLRs) 的抑制剂。Desethyl chloroquine diphosphate 具有抗疟原虫活性。
  14. GC39371 Demethoxyencecalin

    2,2-二甲基-6-乙酰基-2H-1-苯并吡喃

     Demethoxyencecalin 是从一种从向日葵中提取的色烯，具有抗真菌 (antifungal) 活性。
  15. GC39358 Chlorobutanol

    三氯叔丁醇

     Chlorobutanol (Chlorbutol, Chloreton, Chloretone, Chlortran|, trichloro-2-methyl-2-propanol) is a preservative, sedative, hypnotic and weak local anesthetic with antibacterial and antifungal properties.
  16. GC39353 Brilliant Black BN

    食品黑1,E 151

     A sulfonated azo dye with antiviral activity
  17. GC39348 Bifendate

    联苯双酯,DDB

     Bifendate, a synthetic intermediate of schisandrin C, is an anti-HBV drug used in Chinese medicine for the treatment of chronic hepatitis B.
  18. GC39347 Benzimidazole

    苯并咪唑

     Benzimidazole 是一种杂环芳香族有机化合物，是药物化学中重要的药效基团。Benzimidazole 衍生物具有抗癌、抗病毒、抗菌、抗真菌、抗寄生虫、抗炎、质子泵抑制剂、抗凝血等多种生物活性。
  19. GC18413 EIDD-2801

    EIDD2801,EIDD 2801

     A prodrug form of EIDD-1931
  20. GC50573 Click N-Acetylmuramic acid - alkyne 细菌肽聚糖衍生物；适用于“点击”结合荧光染料
  21. GC50493 Furanone C-30

    呋喃酮 C-30

     Furanone C-30 是一种群体感应抑制剂。
  22. GC50483 TH 1217

    ZINC1775962367

     TH 1217 (ZINC1775962367) 是一种有效的选择性 dCTPase pyrophosphatase 1 (dCTPase) 抑制剂，IC50 为 47 nM。
  23. GC50441 Rupintrivir

    (2E,4S)-4-[(2R,5S)-2-(4-氟苄基)-6-甲基-5-(5-甲基异恶唑-3-基甲酰氨基)-4-氧代庚酰氨基]-5-[[(3S)-2-氧代-3-吡咯烷基]-2-戊烯酸乙酯,AG7088

     Rupintrivirvr (AG7088) 是一种抗病毒药物，是一种强效、选择性和不可逆的人鼻病毒 (HRV) 3C 蛋白酶抑制剂。
  24. GC50377 Brequinar sodium

    布喹那钠盐

     A DHODH inhibitor
  25. GC50374 TH 1020 An inhibitor of the TLR5-flagellin protein-protein interaction
  26. GC50140 BRACO 19 trihydrochloride BRACO 19 trihydrochloride是一种有效的端粒酶/端粒抑制剂，IC50值为115±18nM，可防止端粒酶的加帽和催化作用。
  27. GC50054 Quinine hydrochloride

    金鸡纳碱单盐酸盐

     An antimalarial agent
  28. GC50013 AG 1478 hydrochloride

    N-(3-氯苯基)-6,7-二甲氧基-4-喹唑啉胺盐酸盐,Tyrphostin AG-1478 hydrochloride; NSC 693255 hydrochloride

     An inhibitor of EGF receptor kinase
  29. GC39318 DSHS00884

    SSYA10-001

     DSHS00884 是有效的人乳头瘤病毒 E6 抑制剂，IC50 为 10 μM。
  30. GC39317 (S)-Tenofovir

    (S)-替诺福韦; (S)-GS 1278; (S)-PMPA; (S)-TDF

     (S)-Tenofovir ((S)-GS 1278) 是 Tenofovir 的低活性 S 型异构体。Tenofovir 是一种核苷酸逆转录酶 (nucleotide reverse transcriptase) 抑制剂，可用于治疗 HIV 和慢性乙型肝炎 (Hepatitis B; HBV)。
  31. GC39290 Ectoine

    依克多因；四氢甲基嘧啶羧酸

     A microbial metabolite with photoprotectant and anti-inflammatory activities
  32. GC39271 (±)-Naringenin

    (±)-柚皮素

     A citrus-derived flavonoid
  33. GC39265 G0507 G0507 是吡咯并嘧啶二酮化合物，一种有效的 LolCDE ABC 转运蛋白抑制剂。G0507 是大肠杆菌生长的抑制剂，并诱导胞浆外 σE 应激反应。G0507 用作解剖革兰氏阴性细菌中脂蛋白运输的化学探针。
  34. GC39250 Hexyl gallate

    没食子酸己酯,Hexyl 3,4,5-trihydroxybenzoate

     Hexylgallate (Hexyl 3,4,5-trihydroxybenzoate)，没食子酸的烷基酯衍生物，对恶性疟原虫具有很强的抗疟活性，IC50 为 0.11 mM。
  35. GC39239 Rifamycin S

    利福霉素S

     Rifamycin S, a quinone and an antibiotic against Gram-positive bacteria (including MRSA), is a clinical drug used to treat tuberculosis and leprosy. Rifamycin S generates reactive oxygen species (ROS) and inhibits microsomal lipid peroxidation.
  36. GC39238 BRD-K98645985 BRD-K98645985 是一类 12 元大环内酰胺，也是一种 BAF (Brg/Brahma-associated factors) 转录阻遏的抑制剂，EC50 为 ~2.37 µM。BRD-K98645985 结合 ARID1A 特异的 BAF 复合物，防止核小体定位，并有效逆转 HIV-1 潜伏期，并且无 T 细胞毒性。
  37. GC39234 DHODH-IN-2 DHODH-IN-2 是人二氢乳清酸脱氢酶 (HsDHODH) 抑制剂，可抑制麻疹病毒复制，pMIC50 值为 8.6。
  38. GC39196 4-Hydroxyacetophenone

    对羟基苯乙酮; P-hydroxyacetophenone

     4-Hydroxyacetophenone (P-hydroxyacetophenone) 是蒿属植物和木香属植物中主要的保肝促胆化合物，具有抗乙型肝炎病毒作用和抗炎作用。
  39. GC46238 Yatein

    亚太因

     A lignan with diverse biological activities
  40. GC46232 Tiamulin-d10 (hydrochloride)

    泰妙菌素盐酸盐-D10

     An internal standard for the quantification of tiamulin
  41. GC46215 S-Acetyl-L-glutathione

    S-乙酰-L-谷胱甘肽

     A derivative of glutathione
  42. GC46192 Octanoic Acid-13C

    辛酸-1-13C,Caprylic acid-13C

     An internal standard for the quantification of octanoic acid
  43. GC46185 Nimbin

    宁宾

     A limonoid with diverse biological activities
  44. GC46181 N-3-hydroxybutyryl-L-Homoserine lactone

    3-OH-C4-HSL, N-3-hydroxybutanoyl-L-Homoserine lactone, N-3-hydroxybutyryl-L-HSL, N-3-hydroxybutanoyl-L-HSL

     An N-acyl-homoserine lactone
  45. GC46169 Mer-NF5003F

    F 1839M, NF 5003F, Stachybotrydial

     A sesquiterpene with diverse biological activities
  46. GC46149 FR901379 An antifungal lipopeptide
  47. GC46147 Fenvalerate

    氰戊菊酯

     A pyrethroid ester insecticide and acaricide
  48. GC46124 D13 An acylhydrazone antifungal
  49. GC46119 Cholic Acid anilide A synthetic bile acid
  50. GC46100 BHBM An acylhydrazone with antifungal activity
  51. GC46093 Azadirachtin B

    印楝素 B

     An azadirachtin with diverse biological activities

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