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SRPK (serine/arginine-rich protein-specific kinases) specifically phosphorylate their substrate at serine residues in RS domain. It functions in SR splicing factors phosphorylation and splicing regulation. It is involvd in regulation of HBV replication, neuronal apoptosis and muscle development etc.

Products for  SRPK

  1. Cat.No. 产品名称 Information
  2. GC69507 MSC-1186 MSC-1186 是一种高选择性的泛 SRPK 抑制剂。MSC-1186 对 SRPK1、SRPK2 和 SRPK3 具有活性,IC50 值分别为 2.7 nM、81 nM 和 0.6 nM。MSC-1186 可用于癌症研究。
  3. GC65981 SPHINX SPHINX 是 SRPK1 的选择性抑制剂,IC50 值为 0.58 μM。SPHINX 有效地减少体内脉络膜新生血管 (CNV)。SPHINX 可用于老年性黄斑变性的研究。
  4. GC32583 SRPKIN-1 SRPKIN-1是共价,不可逆的SRPK1/2抑制剂,IC50分别为35.6和98nM。有抗血管生成作用。
  5. GC19456 SPHINX31 A potent inhibitor of SRPK1
  6. GC13596 SRPIN340 A selective inhibitor of SRPK1

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