Filovirus(丝状病毒)
Filoviruses is amongst the most lethal of primate pathogens. Filoviruses cause lethal hemorrhagic fever in humans and nonhuman primates. The family Filoviridae includes two genera: Marburgvirus, comprising various strains of the Lake Victoria marburgvirus (MARV); and Ebolavirus (EBOVs), comprising four species including Sudan ebolavirus (SEBOV), Zaire ebolavirus (ZEBOV), Ivory Coast ebolavirus (CIEBOV), and Reston ebolavirus (REBOV); and a tentative species Bundibugyo ebolavirus (BEBOV).
The infections typically affect multiple organs in the body and are often accompanied by hemorrhage (bleeding). Once the virus has been transmitted from an animal host to a human, it can then spread through person-to-person contact.
Products for Filovirus
- Cat.No. 产品名称 Information
-
GC72667
EBOV-IN-1
EBOV-IN-1(com 3.47)是金刚烷二肽哌嗪和埃博拉病毒(EBOV)抑制剂。
-
GC72446
Cosfroviximab
Cosfroviximab(c13C6-FR1)是一种针对埃博拉病毒糖蛋白(EBOV-GP)的小鼠/人嵌合单克隆抗体。
-
GC72436
Porgaviximab
Porgaviximab是一种单克隆抗体,可用于埃博拉感染研究。
-
GC72434
Odesivimab
Odesivimab是一种针对埃博拉病毒糖蛋白的人单克隆抗体,重组组氨酸标记的Makona株埃博拉病毒糖蛋白外结构域蛋白的KD值为7.74nM。
-
GC72425
Maftivimab
Maftivimab (REGN3470-3471-3479)是丝状病毒抑制剂,是美国食品和药物管理局(FDA)批准的药物。
-
GC72421
Larcaviximab
Larcaviximab(c4G7-N)是一种IgG1κ抗埃博拉病毒糖蛋白嵌合单克隆抗体。
-
GC72370
Atoltivimab
Atoltivimab (REGN3470)或mativimab /odesivimab (Inmazeb)是美国食品和药物管理局(FDA)批准的首个针对扎伊尔埃博拉病毒(ebov)感染的单克隆抗体。
-
GC72368
Ansuvimab
Ansuvimab(Ansuvimab-zyk)是一种重组人单克隆IgG1抗体,对扎伊尔埃博拉病毒具有抗病毒活性。
-
GC67627
2'-Deoxy-5'-O-DMT-2'-fluorouridine
2'-Deoxy-5'-O-DMT-2'-fluorouridine 是一种核苷类似物,是 5'-O-DMTr-5-FUDR 的衍生物。2'-Deoxy-5'-O-DMT-2'-fluorouridine 具有有效的抗黄热病 (YFV) 活性。
-
GC43228
Cephaeline
吐根酚碱; (-)-Cephaeline; NSC 32944 free base
An alkaloid with diverse biological activities -
GC32092
Galidesivir (BCX 4430)
加利西韦,BCX4430; Immucillin-A
Galidesivir (BCX 4430) (BCX4430) 是一种腺苷类似物和直接作用的抗病毒剂,可破坏病毒 RNA 依赖性 RNA 聚合酶 (RdRp) 活性。 -
GC32089
Galidesivir hydrochloride (BCX 4430 (hydrochloride))
(2S,3S,4R,5R)-2-(4-氨基-5H-吡咯并[3,2-D]嘧啶-7-基)-5-(羟基甲基)-3,4-吡咯烷二醇单盐酸盐,BCX4430 hydrochloride; Immucillin-A hydrochloride
Galidesivir (BCX4430) hydrochloride 是一种腺苷类似物和直接作用的抗病毒剂,可破坏病毒 RNA 依赖性 RNA 聚合酶 (RdRp) 活性。 -
GC14314
Aloperine
苦豆碱
An alkaloid with diverse biological activities