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Home >> Signaling Pathways >> Proteases >> Endogenous Metabolite

Endogenous Metabolite(内源性代谢物)

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Products for  Endogenous Metabolite

  1. Cat.No. 产品名称 Information
  2. GC38370 N-Acetyl-L-leucine

    N-乙酰-L-亮氨酸

     N-acetyl-L-leucine is an active endogenous metabolite that accelerates vestibular compensation after unilateral labyrinthectomy by action in the cerebellum and thalamus.
  3. GC38369 (±)-Leucine

    DL-亮氨酸,DL-Leucine; (RS)-Leucine

     (±)-Leucine 是一种内源性代谢产物。
  4. GC38368 3-Furanoic acid

    3-糠酸

     3-Furoic acid is an organic acid regularly occurring in urine of healthy individuals.
  5. GC38367 2,4-Dihydroxypyrimidine-5-carboxylic Acid

    脲嘧啶-5-羧酸

     2,4-Dihydroxypyrimidine-5-carboxylic Acid (Uracil 5-carboxylic acid, Isoorotic acid, 5-Carboxyuracil) is an endogenous metabolite.
  6. GC38366 Pyridoxylamine dihydrochloride

    盐酸吡多胺; Pyridoxamine dihydrochloride

    A 4-methylamine form of vitamin B6
  7. GC38364 (R)-Ornithine hydrochloride

    D-鸟氨酸盐酸盐,(R)-Ornithine hydrochloride

    An enantiomer of L-ornithine
  8. GC38363 (R)-pyrrolidine-2-carboxylic acid

    D-脯氨酸,(+)-(R)-Proline; (R)-(+)-Proline; (R)-2-Carboxypyrrolidine; (R)-Proline

     D-proline is an isomer of the naturally occurring amino acid, L-Proline.
  9. GC38362 KSD 2405

    3-羟基苯甲醇

     3-Hydroxybenzyl alcohol is used as an intermediate to produce other chemicals.
  10. GC38360 3-Methylbut-2-enoic acid

    3,3-二甲基丙烯酸

     Senecioic acid (3-Methylcrotonic acid, 3,3-Dimethylacrylic acid, β-Methylcrotonic Acid) is an unsaturated fatty acid found in the pheromones of mealybug species and appears in the urine of patients with 3-Methylcrotonic aciduria.
  11. GC38359 1H-pyrazole

    吡唑

     Pyrazole (1H-pyrazole) is a five membered heteroaromatic ring with two nitrogen atoms is of immense significance. Pyrazole is an indispensable anchor for design and development of new pharmacological agents.
  12. GC38358 5'-Cytidylic acid

    胞苷酸; 5'-Cytidylic acid; 5'-CMP

     A pyrimidine nucleotide
  13. GC38356 Imidazoleacetic acid hydrochloride

    4-咪唑乙酸盐酸盐,Imidazolyl-4-acetic acid hydrochloride

     Imidazole-4(5)-acetic Acid Hydrochloride is a competitive antagonist at GABAC receptors.
  14. GC38327 Sodium 1-hydroxypropane-1,2,3-tricarboxylate hydrate

    异柠檬酸三钠盐

     Isocitric acid (DL-Isocitric acid) trisodium salt is an active endogenous metabolite.
  15. GC38326 NSC 13138

    喹啉-4-羧酸,Cinchoninic acid (6CI,7CI,8CI); 4-Carboxyquinoline

     Quinoline-4-carboxylic acid (4-Carboxyquinoline) is a very important structure in a synthetic medicinal chemistry.
  16. GC38325 N-Acetyl-D-mannosamine monohydrate

    N-乙酰-D-甘露糖胺,Cyclic ManNAc

     A precusor of sialic acid
  17. GC38324 D-Galacturonic acid (hydrate)

    D-半乳糖醛酸

    A monosaccharide
  18. GC38323 Tetrahydro-2H-pyran-2-one

    delta-戊内酯

     δ-Valerolactone (Tetrahydro-2H-pyran-2-one, 5-Valerolactone, oxan-2-one) is an endogenous metabolite.
  19. GC38321 2-Aminopyrimidin-5-ol

    2-氨基-5-羟基嘧啶

     2-Aminopyrimidin-5-ol 是一种内源性代谢产物。
  20. GC38320 L-Methionine sulfoxide

    L-蛋氨酸亚砜,H-Met(O)-OH

     L-Methionine sulfoxide (H-Met(O)-OH)，甲硫氨酸的代谢产物，诱导 M1/classical 巨噬细胞极化，并调节氧化应激和嘌呤能的信号传递参数。
  21. GC38317 Acetamide

    乙酰胺

     Acetamide (ethanamide, Acetic acid amide) is an organic compound that can be used as a plasticizer and an industrial solvent.
  22. GC38301 2-(1H-Indol-3-yl)ethan-1-ol

    色醇; Tryptophol; Indole-3-ethanol

     An indole with diverse biological activities
  23. GC38300 Phytic acid potassium

    植酸二钾

     Phytic acid dipotassium salt (Phytic acid potassium, IP6 (PS)), an endogenous metabolite in rice grain extract and digest, inhibits β-secretase 1 (BACE1) with IC50 of approximately 0.25 μM.
  24. GC38299 (2-Aminoethyl)phosphonic acid

    2-氨基乙基膦酸

     2-Aminoethylphosphonic acid (2-AEP, (2-Aminoethyl)phosphonic acid) is a type of abundant and ubiquitous naturally occurring phosphonate used as sources of phosphorus by many prokaryotic lineages.
  25. GC38298 Pteridine-2,4(1H,3H)-dione

    2,4-二羟基蝶啶

     Pteridine-2,4(1H,3H)-dione 是一种内源性代谢产物。
  26. GC38297 3-Methylindolin-2-one

    3-甲基羟基吲哚

     3-Methylindolin-2-one 是一种内源性代谢产物。
  27. GC38296 (2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride

    盐酸D-甘露糖胺

     An amino monosaccharide
  28. GC38295 N-Acetyl-DL-methionine

    N-乙酰-DL-甲硫氨酸

     N-Acetyl-DL-methionine is an active endogenous metabolite that decreases the hepatic glutathione level in male Bom:NMRI mice.
  29. GC38294 Heptadecanoic acid

    十七烷酸

     An odd-chain saturated fatty acid
  30. GC38293 3-Amino-4-hydroxybenzoic acid

    3-氨基-4-羟基苯甲酸

     3-Amino-4-hydroxybenzoic acid is a monohydroxybenzoic acid.
  31. GC38292 H-Trp-NH2.HCl

    L-色氨酰胺盐酸盐

     An endogenous metabolite of L-tryptophan
  32. GC38291 Indole

    吲哚

     Indole (2,3-Benzopyrrole) is an aromatic heterocyclic organic compound widely distributed in the natural environment and can be produced by a variety of bacteria.
  33. GC38290 NSC 45699

    N-乙酰-L-苯丙氨酸; N-Acetylphenylalanine

     A metabolite of L-phenylalanine
  34. GC38289 N-Methylmethanamine hydrochloride

    二甲胺盐酸盐

     N-Methylmethanamine hydrochloride 是一种内源性代谢产物。
  35. GC38288 Maleimide

    马来酰亚胺

     Maleimide exhibits fluorescence quenching ability and can be used for the specific detection of thiol analytes as fluorogenic probes. Maleimide is also used for production of antibody-drug conjugate (ADC) which is used in cancer research.
  36. GC38287 α-Pyridone

    2-羟基吡啶,Pyridin-2-one; α-Hydroxypyridine

     2-Hydroxypyridine (2-Pyridino, 2-Pyridone) is used in peptide synthesis.
  37. GC38286 5,6-Dimethyl-1H-benzo[d]imidazole

    5,6-二甲基苯并咪唑

     5,6-Dimethylbenzimidazole (5,6-DMB, Dimezol, Dimedazol, 5,6-Dimethyl-1H-benzo[d]imidazole, 5,6-Dimethyl-1H-benzimidazole) is a vitamin B12 precursor.
  38. GC38285 Flavonol

    3-羟基黄酮

     A synthetic flavonol
  39. GC38284 Glycerophosphoric acid disodium salt hydrate

    β-甘油磷酸钠水合物

    Glycerophosphoric acid disodium salt hydrate 是一种内源性代谢物，是一种磷酸酶抑制剂。
  40. GC38283 (3S,4S,5R)-1,3,4,5,6-Pentahydroxyhexan-2-one

    D-塔格糖; D-(-)-Tagatose

     D-Tagatose is an isomer of fructose and is used as a sweetener in beverages, yogurt, creams, and dietetic candy.
  41. GC38282 (R)-5-Oxopyrrolidine-2-carboxylic acid

    D-焦谷氨酸

     A metabolite of D-glutamate
  42. GC38281 2-Hydroxy-2-phenylacetic acid

    扁桃酸,(±)-Mandelic acid; DL-Mandelic acid

     2-羟基-2-苯乙酸（(±)-2-羟基-2-苯乙酸）是一种α-羟基羧酸，已广泛用作医药和精细化学品的中间体。
  43. GC38277 trans-Cyclohexane-1,2-diol

    1,2-环己二醇，顺反混合物

     trans-Cyclohexane-1,2-diol 是一种内源性代谢产物。
  44. GC38276 2-Oxosuccinic acid

    草酰乙酸; 2-Oxosuccinic acid

     2-Oxosuccinic acid（草酰乙酸）是一种α-酮酸，在柠檬酸循环的第一步中草酰乙酸与乙酰辅酶A和水反应形成柠檬酸盐，并在最后一步中通过L-苹果酸的氧化再生。
  45. GC38275 Purine

    嘌呤; Purine (6CI,8CI); 3,5,7-Triazaindole; 3H-Imidazo[4,5-d]pyrimidine; 6H-Imidazo[4,5-d]pyrimidine; 7H-Purine; Isopurine; NSC 753; β-Purine

     An aromatic heterocyclic organic compound
  46. GC38274 Oxalic acid dihydrate

    草酸二水合物

     Oxalic acid dihydrate 是一种内源性代谢产物。
  47. GC38273 Methyl 2-(1H-indol-3-yl)acetate

    吲哚-3-醋酸甲酯

     Methyl 3-indolyacetate is a phytohormone.
  48. GC38272 H-Phg(4-OH)-OH

    L-(+)-对羟基苯甘氨酸,L-p-Hydroxyphenylglycine; 4-Hydroxy-L-phenylglycine; UK 25842

     A CPT1 inhibitor and prodrug form of 4-hydroxyphenylglyoxylic acid
  49. GC38271 1-Hydroxy-2-naphthoic acid

    1-羟基-2-萘甲酸

     1-Hydroxy-2-naphthoic acid is a xenobiotic metabolite produced by the biodegradation of phenanthrene by microorganisms.
  50. GC38270 1-Aminocyclopropane-1-carboxylic acid

    1-氨基环丙烷羧酸

     An NMDA receptor partial agonist
  51. GC38268 Indole-3-acetamide

    3-吲哚乙酰胺

     Indole-3-acetamide是吲哚-3-乙酸的生物合成中间体。

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