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Home >> Signaling Pathways >> Proteases >> Endogenous Metabolite

Endogenous Metabolite(内源性代谢物)

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Products for  Endogenous Metabolite

  1. Cat.No. 产品名称 Information
  2. GC50373 Retrobradykinin 逆缓激肽具有与缓激肽相反的序列。
  3. GC50134 Bengamide B

    Potent inhibitor of NF-κB activation
  4. GC50113 Noradrenaline bitartrate

    L-去甲肾上腺素酒石酸氢盐(酯),Levarterenol tartrate; L-Noradrenaline tartrate

     Norepinephrine (Levarterenol; L-Noradrenaline) tartrate 是一种有效的肾上腺素能受体 (AR) 激动剂。
  5. GC50089 PEAQX tetrasodium salt Potent and GluN2A-selective NMDA antagonist
  6. GC50060 Cerestat

    阿替加奈,CNS 1102

     An NMDA receptor antagonist
  7. GC39306 D-Glucose 6-phosphate disodium salt

    D-葡萄糖-6-磷酸二钠

     D-Glucose-6-phosphate disodium salt 称 6-磷酸葡萄糖，是葡萄糖经过磷酸化 (在第 6 号碳) 之后生成的分子。它是生物细胞中的常见分子，参与磷酸戊糖途径与糖酵解等生化途径。
  8. GC39271 (±)-Naringenin

    (±)-柚皮素

     A citrus-derived flavonoid
  9. GC39223 11-Beta-hydroxyandrostenedione

    4-雄烯-11β-醇-3,17-二酮,4-Androsten-11β-ol-3,17-dione

     11β-Hydroxyandrostenedione是一种内源性、天然存在的?类固醇和雄激素原，主要（如果不是完全）在肾上腺中产生。它与肾上腺产生的肾上腺素(11-ketoandrostenedione; 11-KA4)、11-ketotestosterone?(11-KT) 和11-ketodihydrotestosterone?(11-KDHT)密切相关。可用作指导肾上腺静脉取样中原发性醛固酮增多症亚型的生物标志物，其中从两个肾上腺采集血样以比较每个腺体产生的激素量。
  10. GC39199 Thymopentin acetate

    胸腺五肽醋酸盐

     A pentapeptide fragment of thymopoietin
  11. GC46078 5-Methoxyindole-3-acetic acid

    5-甲氧基吲哚-3-乙酸

     A methoxyindole
  12. GC46041 1,2,3-Trilinoleoyl-rac-glycerol

    甘油三亚油酸酯

     A triacylglycerol
  13. GC39185 Pregnanediol

    孕二醇; NSC 1612; NSC 47462

     Pregnanediol 是一种内源性代谢产物。
  14. GC39173 Phosphorylcholine chloride calcium salt tetrahydrate

    胆碱磷酸氯化钙四水

     Phosphocholine (Phosphorylcholine) chloride calcium salt tetrahydrate is an active endogenous metabolite.
  15. GC39119 Isonicotinic acid

    异烟酸

     Isonicotinic acid (Isoniazid, 4-pyridinecarboxylic acid, p-pyridinecarboxylic acid, 4-Picolinic acid) is a metabolite of isoniazid. It is an isomer of nicotinic acid.
  16. GC39115 Terpinen-4-ol

    4-萜烯醇; 4-Carvomenthenol

     Terpinen-4-ol, a naturally occurring monoterpene, is the main bioactive component of tea-tree oil and has been shown to have many biological activities such as antifungal properties.
  17. GC38958 Sorbic acid

    山梨酸

     Sorbic acid (2,4-Hexadienoic acid) is a naturally occurring compound that originated from the unripe berries of the Rowan Tree. It inhibits various bacteria, including sporeformers, at various stages of their life cycle (germination, outgrowth and cell division).
  18. GC38920 L-Carnitine hydrochloride

    L-肉毒碱盐酸盐; (R)-Carnitine hydrochloride; Levocarnitine hydrochloride

     L-Carnitine ((R)-Carnitine, Levocarnitine) hydrochloride improves oxygen saturation, and inhibits leukotriene synthesis. L-Carnitine hydrochloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation.
  19. GC38885 alpha-D-glucose

    a-无水葡萄糖酯

     Alpha-D-Glucose is a primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is an intermediate in glycolysis/gluconeogenesis pathway.
  20. GC38883 9-Ethyladenine

    9-乙基腺嘌呤

     9-Ethyladenine 是 APRT (腺嘌呤磷酸核糖基转移酶) 的部分有效抑制剂。
  21. GC38882 5-ALA benzyl ester hydrochloride

    5-氨基酮戊酸苄酯盐酸盐,Benzyl-ALA hydrochloride

     5-ALA benzyl ester hydrochloride (Benzyl-ALA hydrochloride) 是一种用作光检测器的原卟啉前体。5-ALA benzyl ester hydrochloride 诱导原卟啉 IX (PPIX) 在结肠癌细胞系中的积聚。
  22. GC45994 Hydrocortisone Acetate

    Cortef Acetate, Hydrin 2, Hydrocortisone 21-Acetate, Hydroxycorticosterone Acetate, 17α-Hydroxycorticosterone Acetate, Isopto-Hydrocortisone

     A synthetic corticosteroid
  23. GC45962 12-hydroxy Lauric Acid

    端羟基12酸

     A hydroxylated fatty acid
  24. GC38859 Tetrahydrocortisone

    四氢可的松

     A metabolite of cortisol
  25. GC38834 Phosphonoacetic acid

    磷酰基乙酸

     Phosphonoacetic acid (PAA) is an active endogenous metabolite that possesses a restricted potential to block DNA biosynthesis. Phosphonoacetic acid exhibits anti-viral activities.
  26. GC38761 Cyclo(his-pro) TFA

    Cyclo(histidyl-proline) TFA; Histidylproline diketopiperazine TFA

     Cyclo(his-pro) TFA (Cyclo(histidyl-proline) TFA) 是一种具有口服活性的，结构上与促甲状腺激素释放激素相关的环状二肽。Cyclo(his-pro) TFA 可以抑制 NF-κB 核积累。Cyclo(his-pro) TFA 可以穿越脑血屏障并影响多种炎症和应激反应。
  27. GC38734 Allotetrahydrocortisol

    异体-3Α-四氢皮质醇,5a-Tetrahydrocortisol

     Allotetrahydrocortisol (5a-Tetrahydrocortisol) 是一种皮质醇的代谢产物。Cortisol 是皮质醇是人体主要的糖皮质激素，在肾上腺皮质产生，在许多生理过程中起着至关重要的作用。
  28. GC38729 2,5-Dimethylpyrazine

    2,5-二甲基吡嗪,NSC 49139

     2,5-Dimethylpyrazine (NSC 49139) is an endogenous metabolite.
  29. GC45909 17α-hydroxy Pregnenolone

    17α-羟基妊娠烯醇酮,NSC 63853

     A metabolite of pregnenolone
  30. GC45705 D-Kynurenine

    犬尿氨酸

     An antagonist of GPR109B
  31. GC45673 7,8-Dihydroneopterin

    7,8-二氢-D-新蝶呤

     An antioxidant
  32. GC38703 NSC 8751

    巴豆酸,(E)-2-Butenoic acid; (E)-Crotonic acid; trans-2-Butenoic acid; trans-Crotonic acid

     NSC 8751 是一种内源性代谢产物。
  33. GC38690 D-Glucuronic acid lactone

    葡醛内酯; 葡糖醛酸內酯; D-Glucurono-6,3-lactone; D-Glucurono-γ-lactone; D-Glucuronolactone; Dicurone; Glucoxy; Glucurolactone; Glucurone

     D-Glucurone is a glucuronic acid derivative that is used for treating canine hepatitis.
  34. GC38689 Poly(4-vinylphenol)

    聚（4-乙基苯酚）

     Poly(4-vinylphenol) 是一种内源性代谢产物。
  35. GC38688 Inosine 5'-monophosphate disodium salt (hydrate)

    肌苷5-单磷酸二钠盐水合物,5'-IMP (disodium)(hydrate

     Disodium 5'-inosinate monohydrate (Inosine 5'-monophosphate disodium salt hydrate) is an endogenous metabolite.
  36. GC38684 (E)-m-Coumaric acid

    3-羟基肉桂酸

     3-hydroxycinnamic acid (meta-Coumaric acid, m-Coumaric acid, m-Coumarate) is an aromatic acid that can be found in vinegar.
  37. GC38670 1-Hydroxyoctadecane

    硬脂醇

     1-Hydroxyoctadecane 是一种内源性代谢产物。
  38. GC38669 3-Hydroxybenzoic acid 3-Hydroxybenzoic acid 是一种内源性代谢产物。
  39. GC38654 Bis(2-ethylhexyl) phthalate

    邻苯二甲酸二(2-乙基己)酯,Bis(2-ethylhexyl) phthalate; Ergoplast FDO; ESBO-D 82

     Bis(2-ethylhexyl) phthalate，通常称为DEHP，是一种合成化合物，主要用作增塑剂。接触Bis(2-ethylhexyl) phthalate会对生物体产生各种不良影响，如生殖和发育受损、癌症、代谢改变以及神经和行为障碍。
  40. GC38644 Glycodeoxycholic Acid

    甘氨脱氧胆酸；甘氨去氧胆酸

    A quantitative analytical standard guaranteed to meet MaxSpec? identity, purity, stability, and concentration specifications
  41. GC38638 Euphol

    大戟二烯醇

     真酚(Euphol)是Euphorbia tirucalli中的主要成分,真酚可逆的抑制丝氨酸水解酶MGL活性(IC50 = 315 nM)。
  42. GC38593 Ethyl glucuronide

    乙基Β-D-葡萄糖醛酸

     Ethyl glucuronide 是一种内源性代谢产物。
  43. GC38587 H-Arg-Lys-OH TFA H-Arg-Lys-OH TFA 是由 L-精氨酸和 L-赖氨酸残基形成的二肽。
  44. GC38574 Cholesteryl arachidonate

    Arachidonic Acid cholesteryl ester, Cholesterol Arachidonate, Cholesterol 5Z,8Z,11Z,14-Z-Eicosatetraenoic Acid ester, 20:4 Cholesteryl ester

     A cholesterol ester
  45. GC38560 Oleoylcarnitine

    CAR 18:1, C18:1 Carnitine, L-Carnitine oleoyl ester, L-Oleoylcarnitine

     A long-chain acylcarnitine
  46. GC38556 1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine 1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine 是一种内源性代谢产物。
  47. GC38552 Tetrahydrocortisol

    氧戊环

     An endogenous metabolite of cortisol
  48. GC38457 Lapaquistat

    T-91485

     Lapaquistat (T-91485) 是一种胆固醇生物合成 cholesterol biosynthesis 的抑制剂，是 TAK-475 的活性代谢产物。Lapaquistat 可以降低他汀类药物在降脂治疗中的肌毒性。
  49. GC38440 Guaiazulene

    愈疮奥

     A sesquiterpene with diverse biological activities
  50. GC38438 Synephrine

    辛弗林; Oxedrine

     Synephrine (Oxedrine), a natural protoalkaloid in the extract of bitter orange and other citrus species, is commonly used for weight loss.
  51. GC38371 (S)-(-)-Phenylethanol

    S-(-)-苯乙醇

     (S)-(-)-1-Phenylethanol ((S)-1-Phenylethanol, (S)-(-)-Phenylethanol) is an enantiomer of 1-Phenylethanol with flavor properties.

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