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Home >> Signaling Pathways >> Proteases >> Endogenous Metabolite

Endogenous Metabolite(内源性代谢物)

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Products for  Endogenous Metabolite

  1. Cat.No. 产品名称 Information
  2. GC38266 Quinoline-2-carboxylic acid

    喹哪啶酸

     Quinaldic acid is a product of l-tryptophan catabolism, via kynurenic acid, found in human urine.
  3. GC38265 (2R,3R)-2,3-Dihydroxysuccinic acid

    L-酒石酸; L-(+)-Tartaric acid

     Tartaric acid (2,3-Dihydroxysuccinic acid, Threaric acid, Racemic acid, Uvic acid, Paratartaric acid, Winestone) is a white crystalline organic acid that occurs naturally in many plants, most notably in grapes. It has several applications for industrial and pharmaceutical use.
  4. GC38264 Ac-Ala-OH

    N-乙酰-L-丙氨酸

     N-Acetyl-L-alanine (NAAL, Ac-Ala-OH) is an active endogenous metabolite.
  5. GC38262 (R)-(-)-1,3-Butanediol

    (R)-(-)-1,3-丁二醇

     (R)-(-)-1,3-Butanediol 可以用于调节糖类脂类代谢。
  6. GC38261 H-allo-Thr-OH

    L-别苏氨酸,H-allo-Thr-OH

     H-allo-Thr-OH 是一种内源性代谢产物。
  7. GC38260 2-Aminobenzenesulfonic acid

    2-氨基苯磺酸

     2-Aminobenzenesulfonic acid (Orthanilic acid, O-Aminobenzenesulfonic acid, Aniline-2-sulfonic acid) is a biological acid with roles in benzoate degradation and microbial metabolism in diverse environments.
  8. GC38259 H-D-cis-Hyp-OH

    顺式-4-羟基-D-脯氨酸；顺-4-羟基-D-脯氨酸

     cis-4-Hydroxy-D-proline (H-D-cis-Hyp-OH) is an endogenous metabolite that can be used to study the specificity and kinetics of D-alanine dehydrogenase.
  9. GC38258 2'-Deoxyadenosine-5'-monophosphate

    2'-脱氧腺苷-5'-单磷酸

     A deoxynucleotide
  10. GC38257 3-Ethoxy-3-oxopropanoic acid

    3-乙氧基-3-氧代丙酸

     Monoethyl malonic acid (Ethyl hydrogen malonate, Monoethyl malonate, 3-Ethoxy-3-oxopropanoic acid) is the major urinary metabolites of ethyl 3-ethoxypropionate (EEP).
  11. GC38249 D-Glucuronic acid

    D-葡萄糖醛酸

     A metabolite of glucose
  12. GC38248 Oxalic Acid

    草酸; Ethanedioic acid

     Oxalic acid (Ethanedioic acid, Wood bleach) is a strong dicarboxylic acid occurring in many plants and vegetables.
  13. GC38246 Undecanoic acid

    十一烷酸,Undecanoate; Hendecanoic acid

     An eleven carbon SFA
  14. GC38243 2,3-Diaminopropanoic acid hydrochloride

    DL-2,3-二胺基丙酸盐酸盐

     DL-2,3-Diaminopropionic acid monohydrochloride (2,3-Diaminopropanoic acid hydrochloride) is an active endogenous metabolite.
  15. GC38242 1,4-Dioxane-2,5-diol

    乙醇醛二聚体(羟基乙醛二聚体)

     Glycolaldehyde dimer (2,5-Dihydroxy-1,4-dioxane, 1,4-Dioxane-2,5-diol, DD) is an active endogenous metabolite that appears moderate absorbent and fluorescent, when it reacts with glycine (Gly)/ammonium sulfate (AS).
  16. GC38235 Cuminaldehyde

    4-异丙基苯甲醛

     4-Isopropylbenzaldehyde (Cuminaldehyde, Cuminic aldehyde, Cuminal), a natural organic compound, is a kind of pharmaceutical intermediate with a pleasant smell and contributes to the aroma of essential oils.
  17. GC38205 cis-​9,​10-​Epoxystearic acid

    cis-9,10-Epoxyoctadecanoic acid

     An epoxy fatty acid
  18. GC38191 2'-Deoxyguanosine monohydrate

    2'-脱氧鸟苷一水合物

     A purine nucleoside with diverse biological activities
  19. GC38190 2-Hydroxyhexanoic acid

    Α-羥己酸

     2-Hydroxyhexanoic acid (2-Hydroxyhexanoic acid) is an endogenous metabolite.
  20. GC38178 D-Methionine sulfoxide

    D-甲硫氨酸亚砜

     D-methionine sulfoxide 是 Methionine sulfoxide 的 D 型异构体。Methionine sulfoxide 是 Methionine 的氧化产物。Methionine 是牛奶或豆类蛋白中的限制性氨基酸，在储存或加工过程中易被氧化。
  21. GC38143 Batilol

    鲨肝醇

     Batyl alcohol (Batilol, Stearyl monoglyceride, 1-O-Octadecylglycerol, Batilolum), isolated from shark liver oil, is also present in yellow bone marrow of animals and has been described as an inflammatory agent.
  22. GC38136 m-Tyramine hydrobromide

    3-羟基苯乙胺氢溴酸盐

     m-Tyramine hydrobromide 是一种内源性微量胺神经调节剂。m-Tyramine hydrobromide 对肾上腺素能 (adrenergic) 和多巴胺能受体 (dopaminergic) 有影响。
  23. GC38058 5-Methoxy-DL-tryptophan

    DL-5-甲氧基色氨酸

     An active metabolite of tryptophan
  24. GC38012 JBSNF-000088

    6-甲氧基-3-吡啶羧胺,6-Methoxynicotinamide

     An inhibitor of NNMT
  25. GA23610 Thymopentin

    胸腺五肽

     A pentapeptide fragment of thymopoietin
  26. GA23362 Phenylac-Gly-OH

    苯乙酰甘氨酸

     Phenylac-Gly-OH是苯乙酸酯的甘氨酸偶联物。肠道微生物群将苯丙酮酸转化为苯乙酸，在肝酶和肾酶的催化作用下，苯乙酸与甘氨酸结合形成Phenylac-Gly-OH。
  27. GA23130 L-Azetidine-2-carboxylic acid

    (S)-(-)-2-羧基环丁胺

     A derivative of L-proline with diverse biological activities
  28. GA23128 L-Anserine . nitrate

    L-鹅肌肽硝酸盐

     L-安丝氨酸。硝酸盐是一种内源性代谢物。
  29. GA23123 L-4,5,6,7-Tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid

    L-4,5,6,7-四氢-1H-咪唑[4,5-C]并吡啶-6-羧酸,(S)-Spinacine

     L-4,5,6,7-四氢-1H-咪唑并[4,5-c]吡啶-6-羧酸是一种内源性代谢物。
  30. GA23027 H-Val-Tyr-OH

    Valyl-tyrosine

     Antihypertensive dipeptide. Acts as ACE inhibitor, IC?? 0.02 mg/ml. G-3585 showed an antihypertensive effect when administered orally to spontaneously hypertensive rats for 28 days.
  31. GA22998 H-Val-Ala-OH

    缬氨酰-丙氨酸,Valyl-alanine

     H-Val-Ala-OH (Valyl-alanine) 是由 L-缬氨酸和 L-丙氨酸残基形成的二肽。
  32. GA22890 H-Ser-His-OH H-Ser-His-OH 是一种具有水解裂解活性的短肽，是一种内源性代谢物。
  33. GA22877 H-Ser(Ac)-OH . HCl

    O-乙酰-L-丝氨酸盐酸盐

     H-Ser(Ac)-OH。 HCl是一种内源性代谢物。
  34. GA22842 H-Pro-Gly-OH H-Pro-Gly-OH 是一种内源性代谢物。
  35. GA22673 H-Lys(Me)₃-OH chloride

    Ne-(Trimethyl)-L-lysine chloride; H-Lys(Me)3-OH chloride

    An amino acid and a precursor in L-carnitine biosynthesis
  36. GA22634 H-Leu-Leu-OMe . HBr

    LLOMe hydrobromide; Leu-Leu methyl ester hydrobromide; H-Leu-Leu-OMe hydrobromide

     H-Leu-Leu-OMe . HBr（亮氨酸-亮氨酸甲酯氢溴化物）是由人类单核细胞或多形核白细胞产生的二肽。H-Leu-Leu-OMe . HBr选择性地清除淋巴细胞，特别是具有细胞毒性的自然杀伤细胞，并诱导内溶酶体途径应激。
  37. GA22523 H-Gly-Val-OH

    甘氨酰-L-缬氨酸

     H-Gly-Val-OH 是一种含有甘氨酸和缬氨酸的二肽。
  38. GA22281 H-DL-δ-Hydroxy-DL-Lys-OH . HCl

    羟赖氨酸

     H-DL-δ；-羟基-DL-Lys-OH。 HCl是一种内源性代谢物。
  39. GA22193 H-D-allo-Thr-OH

    D-别苏氨酸

     H-D-allo-Thr-OH 是 Allothreonine 的 D 型立体异构体。
  40. GA22171 H-Cys-Gly-OH

    谷胱甘肽EP杂质A

     H-Cys-Gly-OH 是一种内源性代谢物，用于疾病诊断。
  41. GA22146 H-cis-Hyp-OH

    顺式-4-羟基-L-脯氨酸

     H-cis-Hyp-OH 是脯氨酸类似物，是胶原蛋白生成的抑制剂。
  42. GA22086 H-Arg-Lys-OH H-Arg-Lys-OH 是由 L-精氨酰和 L-赖氨酸残基形成的二肽 。
  43. GA22021 H-Ala-Phe-OH

    L-Alanyl-L-phenylalanine; H-Ala-Phe-OH

     Ala-Phe was shown to be an efficient enatioselective catalyst in aldol reactions.
  44. GA22010 H-Ala-Leu-OH

    L-丙氨酰-L-亮氨酸,H-Ala-Leu-OH

     Substrate for human kidney dipeptidase.
  45. GA21410 D-α-Hydroxyisocaproic acid

    (R)-2-羟基-4-甲基戊酸,D-α-Hydroxyisocaproic acid

     D-α-羟基异己酸是一种氨基酸代谢物。
  46. GA21297 Cyclo(-Ala-Gly) Cyclo(-Ala-Gly) 是红树林内生真菌 Penicillium thomi 的代谢物，对 A549、HepG2 和 HT29 细胞具有细胞毒性。 IC50 值范围为 9.5 至 18.1 μM。
  47. GA20680 Ac-Val-OH

    N-乙酰-L-缬氨酸
  48. GA20612 Ac-Lys-OH

    N-乙酰-L-赖氨酸

     Ac-Lys-OH 是一种内源性代谢物。
  49. GA20489 Ac-Asn-OH

    N-乙酰-L-天门冬酰胺

     Ac-Asn-OH 是一种内源性代谢物。
  50. GA20387 2,6-Diaminopimelic acid

    2,6-二氨基庚二酸

     2,6-Diaminopimelic acid是一种对称的α,α′-二氨基二羧酸，存在于细菌和高等植物中。
  51. GC45518 N1-Acetylspermidine (hydrochloride)

    N-乙酰精脒盐酸盐

     An acetyl derivative of spermidine

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