Oxalic Acid
(Synonyms: 草酸; Ethanedioic acid) 目录号 : GC38248
Oxalic acid (Ethanedioic acid, Wood bleach) is a strong dicarboxylic acid occurring in many plants and vegetables.
Cas No.:144-62-7
Sample solution is provided at 25 µL, 10mM.
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Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Oxalic acid (Ethanedioic acid, Wood bleach) is a strong dicarboxylic acid occurring in many plants and vegetables.
| Cas No. | 144-62-7 | SDF | |
| 别名 | 草酸; Ethanedioic acid | ||
| Canonical SMILES | OC(C(O)=O)=O | ||
| 分子式 | C2H2O4 | 分子量 | 90.03 |
| 溶解度 | DMSO : 18mg/mL | 储存条件 | Store at -20°C |
| General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。 为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。 |
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| Shipping Condition | 评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备RT，或根据请求配备蓝冰。 | ||
| 制备储备液 | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 11.1074 mL | 55.537 mL | 111.0741 mL |
| 5 mM | 2.2215 mL | 11.1074 mL | 22.2148 mL |
| 10 mM | 1.1107 mL | 5.5537 mL | 11.1074 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。
Oxalic Acid, a molecule at the crossroads of bacterial-fungal interactions
Adv Appl Microbiol 2019;106:49-77.PMID:30798804DOI:10.1016/bs.aambs.2018.10.001.
Oxalic Acid is the most ubiquitous and common low molecular weight organic acid produced by living organisms. Oxalic Acid is produced by fungi, bacteria, plants, and animals. The aim of this review is to give an overview of current knowledge about the microbial cycling of Oxalic Acid through ecosystems. Here we review the production and degradation of Oxalic Acid, as well as its implications in the metabolism for fungi, bacteria, plants, and animals. Indeed, fungi are well known producers of Oxalic Acid, while bacteria are considered Oxalic Acid consumers. However, this framework may need to be modified, because the ability of fungi to degrade Oxalic Acid and the ability of bacteria to produce it, have been poorly investigated. Finally, we will highlight the role of fungi and bacteria in Oxalic Acid cycling in soil, plant and animal ecosystems.
Oxalic Acid and sclerotial differentiation of Polyporus umbellatus
Sci Rep 2015 Jun 1;5:10759.PMID:26030006DOI:10.1038/srep10759.
The present investigation aimed to uncover the effects of exogenous Oxalic Acid during the sclerotial formation of Polyporus umbellatus, with an emphasis on determining the content of the endogenic Oxalic Acid in the fungus. To this end, the Oxalic Acid content of the vegetative mycelia, sclerotia, culture mediums and sclerotial exudate were measured using High Performance Liquid Chromatography (HPLC). Furthermore, the lipid peroxidation was estimated by detecting thiobarbituric bituric acid reactive substances (TBARS). The results showed that the exogenous Oxalic Acid caused a delay in sclerotial differentiation (of up to 9 or more days), suppressed the sclerotial biomass and decreased the lipid peroxidation significantly in a concentration-dependent manner. Oxalic Acid was found at very low levels in the mycelia and the maltose medium, whereas it was found at high levels in the mycelia and sucrose medium. After sclerotial differentiation, Oxalic Acid accumulated at high levels in both the sclerotia and the sclerotial exudate. Oxalic Acid was therefore found to inhibit P. umbellatus sclerotial formation.
Excessive Oxalic Acid Secreted by Sparassis latifolia Inhibits the Growth of Mycelia during Its Saprophytic Process
Cells 2022 Aug 5;11(15):2423.PMID:35954267DOI:10.3390/cells11152423.
Sparassis latifolia is an edible and medicinal mushroom in Asia commercially cultivated on substrates containing pine sawdust. Its slow mycelial growth rate greatly increases the cultivation cycle. In this study, we mainly studied the role of Oxalic Acid (OA) secreted by S. latifolia in its saprophytic process. Our results show that crystals observed on the mycelial surface contained calcium oxalate monohydrate (COM) and calcium oxalate dihydrate (COD) according to X-ray diffraction (XRD). Vegetative mycelia secreted large amounts of OA during extended culture periods. However, high concentrations of OA decreased the mycelial growth rate significantly. Moreover, the degradation of lignocellulose was significantly inhibited under high concentrations of OA. These changes could be attributed to the significantly decreased activities of lignocellulose-degrading enzymes. In conclusion, by establishing a link between OA secretion by the mycelium and the slow growth rate of its saprophytic process, this work provides fundamental information for shortening the cultivation cycle of S. latifolia.
Oxalic Acid enhances bioremediation of Cr(VI) contaminated soil using Penicillium oxalicum SL2
Chemosphere 2023 Jan;311(Pt 1):136973.PMID:36283433DOI:10.1016/j.chemosphere.2022.136973.
Oxalic Acid is the most abundant low molecular weight organic acid (LMWOA) in many environments and offers enormous prospects for treating Cr(VI) contamination. In this study, laboratory batch experiments were conducted to estimate the roles of Oxalic Acid in Cr(VI) removal by Penicillium oxalicum SL2. Oxalic Acid changed the initial pH and provided a suitable condition for the growth of strain SL2 when the penicillium was applied to bioremediation of Cr(VI) contamination in alkaline soil. Gompertz model analysis indicated that initial pH affected the lag time of the growth curve of strain SL2. Scanning electron microscopy and scanning transmission X-ray microscopy analysis showed strain SL2 sufficiently contacted with contaminated soil and reduced Cr(VI) to Cr(III) in the hyphae. The results suggested that Oxalic Acid could enhance the bioremediation efficiency of strain SL2 though improving chromium bioleaching from the contaminated soil and strengthening Cr(VI) removal in the leaching solution. This study provided Oxalic Acid as a green reagent for stimulating Cr(VI) removal by strain SL2 and would expand knowledge on the roles of LMWOA in Cr(VI) bioremediation.
Rock phosphate solubilization by abiotic and fungal-produced Oxalic Acid: reaction parameters and bioleaching potential
Microb Biotechnol 2022 Apr;15(4):1189-1202.PMID:33710773DOI:10.1111/1751-7915.13792.
Oxalic acid-producing fungi play an important role in biogeochemical transformations of rocks and minerals and possess biotechnological potential for extraction of valuable elements from primary or waste ores and other solid matrices. This research investigates the extraction of phosphate from rock phosphate (RP) by Oxalic Acid. Reaction parameters were derived using pure Oxalic Acid solutions to solubilize RP. It was found that the Oxalic Acid concentration was the main factor driving reaction kinetics. Excess Oxalic Acid could retard the reaction due to calcium oxalate encrustation on RP surfaces. However, complete P extraction was reached at stoichiometric proportions of apatite and Oxalic Acid. This reaction reached completion after 168 h, although most of the P (up to 75%) was released in less than 1 h. Most of the Ca released from the apatite formed sparingly soluble calcium oxalate minerals, with a predominance of whewellite over weddellite. Bioleaching of RP employing biomass-free spent culture filtrates containing Oxalic Acid (100 mM) produced by Aspergillus niger extracted ~ 74% of the P contained in the RP. These findings contribute to a better understanding of the reaction between apatite and Oxalic Acid and provide insights for potential applications of this process for biotechnological production of phosphate fertilizer.