1,4-Dioxane-2,5-diol
(Synonyms: 乙醇醛二聚体(羟基乙醛二聚体)) 目录号 : GC38242
Glycolaldehyde dimer (2,5-Dihydroxy-1,4-dioxane, 1,4-Dioxane-2,5-diol, DD) is an active endogenous metabolite that appears moderate absorbent and fluorescent, when it reacts with glycine (Gly)/ammonium sulfate (AS).
Cas No.:23147-58-2
Sample solution is provided at 25 µL, 10mM.
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Quality Control & SDS
- View current batch:
- Purity: >95.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Glycolaldehyde dimer (2,5-Dihydroxy-1,4-dioxane, 1,4-Dioxane-2,5-diol, DD) is an active endogenous metabolite that appears moderate absorbent and fluorescent, when it reacts with glycine (Gly)/ammonium sulfate (AS).
| Cas No. | 23147-58-2 | SDF | |
| 别名 | 乙醇醛二聚体(羟基乙醛二聚体) | ||
| Canonical SMILES | OC1OCC(O)OC1 | ||
| 分子式 | C4H8O4 | 分子量 | 120.1 |
| 溶解度 | Soluble in DMSO | 储存条件 | Store at -20°C |
| General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。 为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。 |
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| Shipping Condition | 评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备RT，或根据请求配备蓝冰。 | ||
| 制备储备液 | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 8.3264 mL | 41.632 mL | 83.2639 mL |
| 5 mM | 1.6653 mL | 8.3264 mL | 16.6528 mL |
| 10 mM | 0.8326 mL | 4.1632 mL | 8.3264 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。
Aqueous brown carbon formation by aldehyde compounds reaction with Glycine/Ammonium sulfate
Spectrochim Acta A Mol Biomol Spectrosc 2021 Mar 5;248:119230.PMID:33310608DOI:10.1016/j.saa.2020.119230
Brown carbon (BrC) can absorb solar radiation in the ultraviolet (UV) and near visible (Vis) regions, which plays an important role in the Earth's radiative balance and global climate. 1,4-Dioxane-2,5-diol (DD), glyoxal (GX) and acetaldehyde (AAld) appeared moderate absorbent and fluorescent, when each of them reaction with glycine (Gly)/ammonium sulfate (AS). Combined with the previous experimental studies of the methylglyoxal (MG), GX reaction with GX/AS, novelty conclusions are as following: the absorbance of the reaction products in the same reaction time followed the order: MG-Gly＞DD-Gly＞GX-Gly＞AAld-Gly, DD-AS＞MG-AS＞GX-AS＞AAld-AS. And for the same aldehyde compound reaction with Gly the reaction rate was faster than with AS. Three-dimensional excitation-emission matrix (EEM) plot showed that, with the increasing of reaction time, red shift of emission peak occurred in MG-Gly/AS and GX-Gly, no shift occurred in DD-Gly/AS and AAld-Gly, and blue shift occurred in GX-AS. The H2O2 oxidation photolysis results showed that the effective H2O2 oxidation photolysis rate constants (k) in the visible region are larger than in UV region for the reaction MG, GX, DD with Gly. But for AAld-Gly system, the k in the visible region is smaller than in the UV region. Besides, the reaction MG, GX, DD, AAld with Gly clearly showed that the presence of abundant organic products by Liquid chromatography/mass spectrometry (LC/MS) analysis.