Home>>Signaling Pathways>> Proteases>> Endogenous Metabolite>>NSC 45699

NSC 45699 Sale

(Synonyms: N-乙酰-L-苯丙氨酸; N-Acetylphenylalanine) 目录号 : GC38290

A metabolite of L-phenylalanine

NSC 45699 Chemical Structure

Cas No.:2018-61-3

规格 价格 库存 购买数量
100mg
¥450.00
现货
200mg 待询 待询
500mg 待询 待询

电话:400-920-5774 Email: sales@glpbio.cn

Customer Reviews

Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.

产品文档

Quality Control & SDS

View current batch:

产品描述

N-Acetyl-L-phenylalanine is a metabolite of L-phenylalanine .1 It is formed from L-phenylalanine by gut microbiota. Serum levels of N-acetyl-L-phenylalanine are increased in male COVID-19 patients compared with female COVID-19 patients and individuals without COVID-19, and hippocampal levels of N-acetyl-L-phenylalanine are increased in postmortem brain tissue isolated from patients with Alzheimer's disease.1,2 Urinary levels of N-acetyl-L-phenylalanine are negatively correlated with phthalate exposure in normal weight, but not overweight, children.3

1.Escarcega, R.D., Honarpisheh, P., Colpo, G.D., et al.Sex differences in global metabolomic profiles of COVID-19 patientsCell Death Dis.13(5)461(2022) 2.Liu, P., Yang, Q., Yu, N., et al.Phenylalanine metabolism is dysregulated in human hippocampus with Alzheimer's disease related pathological changesJ. Alzheimers Dis.83(2)609-622(2021) 3.Xia, B., Zhu, Q., Zhao, Y., et al.Phthalate exposure and childhood overweight and obesity: Urinary metabolomic evidenceEnviron. Int.121(Pt 1)159-168(2018)

Chemical Properties

Cas No. 2018-61-3 SDF
别名 N-乙酰-L-苯丙氨酸; N-Acetylphenylalanine
Canonical SMILES O=C(O)[C@H](CC1=CC=CC=C1)NC(C)=O
分子式 C11H13NO3 分子量 207.23
溶解度 DMSO: 100 mg/mL (482.56 mM); Water: 7.69 mg/mL (37.11 mM) 储存条件 Store at -20°C
General tips 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

制备储备液
1 mg 5 mg 10 mg
1 mM 4.8256 mL 24.1278 mL 48.2556 mL
5 mM 0.9651 mL 4.8256 mL 9.6511 mL
10 mM 0.4826 mL 2.4128 mL 4.8256 mL
  • 摩尔浓度计算器

  • 稀释计算器

  • 分子量计算器

质量
=
浓度
x
体积
x
分子量
 
 
 
*在配置溶液时,请务必参考产品标签上、MSDS / COA(可在Glpbio的产品页面获得)批次特异的分子量使用本工具。

计算

动物体内配方计算器 (澄清溶液)

第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量)
给药剂量 mg/kg 动物平均体重 g 每只动物给药体积 ul 动物数量
第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系GLPBIO为您提供正确的澄清溶液配方)
% DMSO % % Tween 80 % saline
计算重置