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Home >> Signaling Pathways >> JAK/STAT Signaling

JAK/STAT Signaling(JAK/STAT 信号通路)

Products for  JAK/STAT Signaling

  1. Cat.No. 产品名称 Information
  2. GC13647 STAT5 Inhibitor Prevents activation of STAT5 via its SH2 domain
  3. GC12138 5,15-DPP A STAT3 inhibitor
  4. GC10643 Pimozide A dopamine receptor antagonist
  5. GC14103 NSC228155 An EGFR activator and inhibitor of KID-KIX interactions
  6. GC15370 Olmutinib (HM61713, BI 1482694) An inhibitor of mutant EGFR
  7. GC12712 NT157 IRS-1/2 抑制剂，抑制 IGF-1R 和 STAT3 信号通路
  8. GC10439 APTSTAT3-9R APTSTAT3-9R 是一种特异性 STAT3 结合肽，通过特异性阻断 STAT3 磷酸化来抑制 STAT3 活化和下游信号传导。 APTSTAT3-9R 发挥抗增殖作用和抗肿瘤活性。
  9. GC17761 STA-21 A STAT3 inhibitor
  10. GC12038 RG 13022 An inhibitor of EGF receptor kinase
  11. GC12281 EAI045 A potent inhibitor of mutant EGFRs
  12. GC11474 Napabucasin An inhibitor of cancer cell stemness
  13. GC10341 Peficitinb (ASP015K, JNJ-54781532) A JAK inhibitor
  14. GC16875 FLLL32 An inhibitor of JAK2/STAT3 signaling
  15. GC11652 CHZ868 CHZ868 是一种 II 型 JAK2 抑制剂，在 EPOR JAK2 WT Ba/F3 细胞中的 IC50 为 0.17 μM。
  16. GC13143 AZD3759 A brain penetrant inhibitor of EGFR
  17. GC14938 PF-03394197(Oclacitinib) A JAK family kinase inhibitor
  18. GC17790 CL-387785 (EKI-785) An irreversible inhibitor of EGFR kinase activity
  19. GC16321 EGF816 An inhibitor of mutant EGFR
  20. GC14857 LFM-A13 A BTK inhibitor
  21. GC12955 AZ5104 An active metabolite of AZD 9291
  22. GC17916 Poziotinib An inhibitor of EGFRs
  23. GC16208 HO-3867 A selective STAT3 inhibitor
  24. GC13279 Corylifol A A flavonoid with diverse biological activities
  25. GC14658 SH-4-54 A STAT3 inhibitor
  26. GC11209 Cerdulatinib (PRT062070) A dual inhibitor of Syk and JAKs
  27. GC13213 WZ3146 An inhibitor of mutant EGFR
  28. GC11990 TCS-PIM-1-4a TCS-PIM-1-4a (SMI-4a) 是一种泛 Pim 激酶抑制剂，通过激活 AMPK 来阻断 mTORC1 的活性。 TCS-PIM-1-4a 可杀死多种髓系和淋巴系细胞系（IC50 值范围为 0.8 μM 至 40 μM）。
  29. GC17222 GLPG0634 analogue GLPG0634 类似物 (Compoun 176) 是一种广谱 JAK 抑制剂，对 JAK1、JAK2 和 JAK3 的 IC50 值 <100 nM。
  30. GC15731 L002 A p300 acetyltransferase inhibitor
  31. GC15950 CGP 52411 A phthalimide with diverse biological activities
  32. GC15925 PD 158780 An ErbB receptor family inhibitor
  33. GC13168 AG 825 An inhibitor of Her2/Neu tyrosine kinase activity
  34. GC11744 AG 555 A tyrphostin EGFR inhibitor
  35. GC14494 AG 99 An inhibitor of EGF receptor kinase
  36. GC14854 Colivelin A potent STAT3 activator and neuroprotective agent
  37. GC12359 Hispidulin A flavonoid with diverse biological activities
  38. GC16021 Lavendustin A A selective inhibitor of EGF receptor-associated tyrosine kinase
  39. GC10889 Artesunate An antimalarial compound
  40. GC18126 Balsalazide A prodrug form of 5-ASA
  41. GC15901 Niclosamide monohydrate An anthelmintic mitochondrial uncoupler
  42. GC15271 Tyrphostin AG 879 A non-specific tyrphostin ErbB2 inhibitor
  43. GC14170 Nifuroxazide A nitrofuran antibiotic
  44. GC13586 Niclosamide An anthelmintic mitochondrial uncoupler
  45. GC10250 Mubritinib (TAK 165) A selective inhibitor of HER2
  46. GC13854 AG-490 (Tyrphostin B42) AG-490是EGFR抑制剂,IC50为0.1 µM, AG-490对JAK2也有抑制作用。.
  47. GC12579 GLPG0634 A JAK1 inhibitor
  48. GC16698 AZD-9291 mesylate

    An inhibitor of mutant EGFR
  49. GC16308 AZD-9291

    An inhibitor of mutant EGFR
  50. GC17982 Icotinib An EGFR inhibitor
  51. GC11126 Mutant EGFR inhibitor Mutant EGFR inhibitor 是从专利WO 2013014448 A1中提取的一种有效的选择性突变EGFR抑制剂；抑制 EGFRL858R、EGFRExon 19 缺失和 EGFRT790M。

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