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Home >> Signaling Pathways >> Immunology/Inflammation >> Reactive Oxygen Species

Reactive Oxygen Species(活性氧)

Reactive oxygen species (ROS), such as superoxide anion (O2-), hydrogen peroxide (H2O2), and hydroxyl radical (HO•), consist of radical and non-radical oxygen species formed by the partial reduction of oxygen. Cellular ROS are generated endogenously during mitochondrial oxidative metabolism as well as in cellular response to xenobiotics, cytokines, and bacterial invasion.

ROS also activates MAPK pathways by the direct inhibition of MAPK phosphatases. Through PTEN, the PI3K pathway is subject to reversible redox regulation by ROS generated by growth factor stimulation. The activation of autophagy may be a cellular defense mechanism in response to ROS.

Products for  Reactive Oxygen Species

  1. Cat.No. 产品名称 Information
  2. GC60693 Chitoheptaose heptahydrochloride Chitoheptaoseheptahydrochloride是一种具有抗氧化，抗炎，抗凋亡和心脏保护作用的壳聚糖寡糖。Chitoheptaoseheptahydrochloride显着增强了小麦幼苗的生长和光合作用参数。
  3. GN10518 Chitosamine hydrochloride An amino monosaccharide
  4. GC68039 Chlorin e6 trimethyl ester Chlorin e6 trimethyl ester，是甲基脱镁叶绿酸-a 的衍生物，是一种可用于光动力疗法 (PDT) 的光敏剂。
  5. GN10308 Chlorogenic acid

    A phenolic natural product with antioxidant activity
  6. GN10662 Cichoric Acid Extracted from Cichorium intybus L;Suitability:Methanol,DMSO;Store the product in sealed,cool and dry condition
  7. GC38680 Citronellol A monoterpene
  8. GC65124 CL097 hydrochloride CL097 是一种有效的 TLR7 和 TLR8 激动剂，可在巨噬细胞中诱导促炎细胞因子。CL097 诱导 NADPH 氧化酶启动活性，导致 fMLF 刺激的 ROS 产生增加。
  9. GC40632 CMS121 A substituted quinoline with diverse biological activities
  10. GN10668 Coenzyme Q10 A cofactor in the electron transport chain
  11. GC47116 Coenzyme Q10-d6 An internal standard for the quantification of CoQ10
  12. GC43297 Coenzyme Q2 A biosynthetic precursor to CoQ10 and an inhibitor of mitochondrial complex I
  13. GC43316 Coumarin Boronic Acid A fluorescent probe for direct detection of peroxynitrite
  14. GC43317 Coumarin Boronic Acid pinacolate ester A fluorescent probe for detection of peroxynitrite
  15. GC52164 Cu-ATSP A copper-containing bis(thiosemicarbazone) complex
  16. GC49557 Cu-GTSM A copper-containing compound with diverse biological activities
  17. GC43335 Cyanidin 3-O-arabinoside An anthocyanin antioxidant
  18. GC18488 Cyclo(L-Leu-L-Trp) A diketopiperazine metabolite
  19. GC65545 Cyclo(L-Phe-L-Pro) Cyclo(L-Phe-L-Pro) 可从 Pseudomonas fluorescens 和 Pseudomonas alcaligenes 无细胞培养上清液中分离得到，是一种抗真菌环状二肽。Cyclo(L-Phe-L-Pro)通过干扰视黄酸诱导基因-I (RIG-I) 的激活来抑制 IFN-β 产生。Cyclo(L-Phe-L-Pro) 还具有自由基清除活性，IC50 为 24 µM。
  20. GC34894 CycLuc1 CycLuc1是一种可渗透血脑屏障的荧光素酶(luciferase)底物。
  21. GC45877 CYM 5478 An S1P2 agonist
  22. GN10698 Cynarin Cynarin 是一种抗窒息剂，具有多种生物活性，包括抗氧化、抗组胺和抗病毒活性。
  23. GC43352 CYPMPO A novel spin trap for hydroxyl and superoxide radical detection
  24. GC33779 Cysteamine (β-Mercaptoethylamine) 2-Aminoethanethiol (cysteamine, β-Mercaptoethylamine, 2-Mercaptoethylamine, Thioethanolamine, Mercaptamine) is a radiation-protective agent that oxidizes in air to form cystamine.
  25. GC13502 Cysteamine HCl A radioprotective aminothiol
  26. GC49868 D-α-Tocopheryl Quinone An oxidative metabolite of vitamin E
  27. GC33606 D-(+)-Glucono-1,5-lactone (Gluconic acid lactone) Gluconolactone is a naturally occurring polyhydroxy acid with metal chelating, moisturizing and antioxidant activity.
  28. GC18583 D-α-Hydroxyglutaric Acid

    An α-hydroxy acid
  29. GC16306 Dapsone An anti-inflammatory, antimalarial, and antibacterial compound
  30. GC47172 Dapsone-d8 An internal standard for the quantification of daspone
  31. GC16795 DCA DCA 是癌细胞中的代谢调节剂'；具有抗癌活性的线粒体。 DCA 抑制 PDHK，导致肿瘤微环境中的乳酸减少。 DCA 增加活性氧 (ROS) 生成并促进癌细胞凋亡。 DCA 也可作为 NKCC 抑制剂。
  32. GC43410 DEPMPO A spin trap for superoxide radical detection
  33. GC43411 DEPMPO-biotin A biotinylated spin trap
  34. GC43439 Diallyl Trisulfide A natural H2S donor
  35. GC18517 Diapocynin An inhibitor of NADPH-oxidase
  36. GC45662 Dieugenol A neolignan with antioxidative and antiparasitic activities
  37. GC43462 Dihydrolipoic Acid A reduced form of α-lipoic acid
  38. GC47234 Diosmetin-d3 An internal standard for the quantification of diosmetin
  39. GC12520 Diphenyleneiodonium chloride A NOX inhibitor
  40. GC47238 Diquat (bromide) An herbicide
  41. GC10981 Disodium (R)-2-Hydroxyglutarate An α-hydroxy acid
  42. GC11702 DL-Carnitine HCl DL-Carnitine HCl 存在两种异构体，称为 D 和 L。
  43. GC49081 DL-o-Tyrosine A phenylalanine hydroxylation product
  44. GC40557 DMNQ Inducer of intracellular ROS generation
  45. GC43569 DPPP A fluorescent probe for detection of hydroperoxides
  46. GC10331 Ebselen A peroxynitrite scavenger
  47. GC38149 Ecabet sodium An antiulcerative and gastroprotective agent
  48. GN10422 Echinacoside A glycoside with diverse biological activities
  49. GN10504 Echinocystic acid A triterpene with diverse biological activities
  50. GC32887 Efaproxiral (RSR13) An allosteric hemoglobin modifier
  51. GC14586 Efaproxiral Sodium An allosteric hemoglobin modifier

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