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Chamazulene Sale

(Synonyms: 母菊薁) 目录号 : GC52081

A terpene with anti-inflammatory and antioxidant activities

Chamazulene Chemical Structure

Cas No.:529-05-5

规格 价格 库存 购买数量
1 mg
¥2,998.00
现货
5 mg
¥13,498.00
现货
10 mg
¥16,496.00
现货

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Sample solution is provided at 25 µL, 10mM.

产品文档

Quality Control & SDS

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产品描述

Chamazulene is a terpene that has been found in chamomile (M. recutita) flowers and has anti-inflammatory and antioxidant activities.1 It reduces increases in matrix metalloproteinase-3 (MMP-3), MMP-9, COX-2, inducible nitric oxide synthase (iNOS), and p65 NF-κB levels in IL-1β-stimulated primary rat chondrocytes when used at a concentration of 10 µg/ml. Chamazulene (10 and 20 µg/ml) reduces IL-1β-induced production of malondialdehyde (MDA) and increases levels of superoxide dismutase (SOD), catalase, and glutathione peroxidase (GPX) in primary rat chondrocytes. In vivo, chamazulene (25 and 50 mg/kg) reduces hind paw volume, serum levels of MDA, TNF-α, and IL-6, and cartilage erosion in a rat model of osteoarthritis induced by complete Freund’s adjuvant (CFA).

1.Ma, D., He, J., and He, D.Chamazulene reverses osteoarthritic inflammation through regulation of matrix metalloproteinases (MMPs) and NF-kβ pathway in in-vitro and in-vivo modelsBiosci. Biotechol. Biochem.84(2)402-410(2020)

Chemical Properties

Cas No. 529-05-5 SDF Download SDF
别名 母菊薁
Canonical SMILES CCC1=CC=C(C)C2=CC=C(C)C2=C1
分子式 C14H16 分子量 184.3
溶解度 Ethanol: soluble,Water: very slightly soluble 储存条件 -20°C
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储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 5.4259 mL 27.1297 mL 54.2594 mL
5 mM 1.0852 mL 5.4259 mL 10.8519 mL
10 mM 0.5426 mL 2.713 mL 5.4259 mL
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