Endogenous Metabolite(内源性代谢物)

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Products for Endogenous Metabolite

Cat.No. 产品名称 Information
GC33594 Cytosine
胞嘧啶
A pyrimidine base
GC33526 5-Methylcytidine
5-甲基胞苷
A modified nucleoside
GC33525 3-Methyluridine
3-甲基尿苷,N3-Methyluridine
3-Methyluridine是细胞RNA的修饰核苷。
GC33519 2,5-Dihydroxybenzoic acid
2,5-二羟基苯甲酸
A benzoic acid with diverse biological activities
GC33518 N-Acetylputrescine hydrochloride
N-(4-氨基丁基)-乙酰胺
N-Acetylputrescinehydrochloride是一种腐胺衍生物。
GC33514 5-Methyluridine
5-甲基尿苷
A pyrimidine nucleoside
GC33504 4-Acetamidobutanoic acid (N-acetyl GABA)
4-乙酰氨基丁酸,N-acetyl GABA
A GABA derivative
GC33502 5,6-Dihydrouridine
5,6-二氢尿苷
A pyrimidine nucleoside and derivative of uridine
GC33496 2-(Methylamino)-1H-purin-6(7H)-one (N2-methylguanine)
6-羟基-2-氨甲基嘌呤,N2-methylguanine
2-(Methylamino)-1H-purin-6(7H)-one (N2-methylguanine) (N2-Methylguanine) 是一种修饰的核苷。
GC33471 p-Hydroxycinnamic acid (NSC 59260)
对羟基肉桂酸
p-Hydroxy-cinnamic Acid has in vitro antimalarial activity and in vivo anti-osteoporotic properties.
GC33463 1-Methyladenosine
1-甲基腺苷
1-甲基腺苷是一种在1 位带有甲基取代基的甲基腺苷。它具有作为人体代谢物的作用，在功能上与腺苷有关
GC33462 Phenylacetylglutamine (NSC 203800)
苯乙酰谷氨酰胺; NSC 203800; Phenylacetyl-L-glutamine
Phenylacetylglutamine (NSC 203800)是氨基酸发酵产生的肠绞痛微生物代谢物，苯乙酰谷氨酰胺是氨基酸发酵产生的肠绞痛微生物代谢物，它来源于谷氨酰胺与苯乙酸的结合，苯乙酸几乎完全来自于微生物对苯丙氨酸的转化。
GC33460 D-Mannose
D-甘露糖
An aldohexose monosaccharide
GC33459 delta-Valerobetaine Delta-Valerobetaine 是三甲胺 N-氧化物 (TMAO) 的前体。
GC33455 N-Acetylornithine
(S)-2-乙酰氨基-5-氨基戊酸
An intermediate in arginine and proline metabolism
GC33450 7-Dehydrocholesterol
7-去氢胆固醇
An immediate precursor to cholesterol
GC33445 O-Acetylserine (O-Acetyl-L-serine)
O-乙酰-L-丝氨酸; O-Acetyl-L-serine
O-Acetylserine is an intermediate in the biosynthesis of the common amino acid cysteine in bacteria and plants.
GC33436 3-Indoleacetic acid (Indole-3-acetic acid)
3-吲哚乙酸; Indole-3-acetic acid; 3-IAA
3-吲哚乙酸（Indole-3-乙酸）（Indole-3-乙酸）是生长素类中最常见的天然植物生长激素。
GC33383 3-Hydroxycapric acid
3-羟基癸酸
A hydroxy fatty acid
GC33140 N2,N2-Dimethylguanosine
N2,N2-二甲基鸟苷
A methylated purine nucleoside
GC32943 3-(Methylthio)propionic acid (3-Methylsulfanylpropionic acid)
3-甲基硫代丙酸,3-Methylsulfanylpropionic acid
3-(Methylthio)propionic acid (3-methylthiopropionate, 4-Thiapentanoic acid, 3-Methylsulfanylpropionic acid) is a thia fatty acid acid consisting of propionic acid with a methylthio substituent at the 3-position and an intermediate in mammalian methionine metabolism in vitro.
GC32732 Hyaluronic acid
玻尿酸; Hyaluronan; Hyaluronate
透明质酸 (HA) 是由双糖的重复单元组成的生物聚合物，其中包括通过 β- (1 4) 和 β- (1 3) 糖苷连接的 D- 葡萄糖醛酸分子和 N- 乙酰氨基葡萄糖分子。
GC32608 5-Amino-4-oxopentanoic acid
5-氨基乙酰丙酸; 5-ALA; δ-Aminolevulinic acid; 5-Amino-4-oxopentanoic acid
5-Amino-4-oxopentanoic acid是一种天然存在的非蛋白原性氨基酸，是光敏剂原卟啉IX（PpIX）的前药。5-Amino-4-oxopentanoic acid可以被波长约为635nm（580至740nm）的激光激活，发出红色荧光（620至710nm），作为多种癌症的光诊断剂。
GC32604 Angiotensinogen (1-14), human A synthetic peptide precursor of angiotensin I
GC32578 Docosatrienoic Acid (cis-13,16,19-docosatrienoic acid)
顺13,16,19-二十二碳三烯酸,cis-13,16,19-docosatrienoic acid; (13Z,16Z,19Z)-13,16,19-Docosatrienoic acid
A rare ω-3 fatty acid
GC32483 4,6-Dioxoheptanoic acid
4,6-二氧代庚酸
An inhibitor of δ-aminolevulinic acid dehydratase
GC32470 Coenzyme Q9 (Ubiquinone Q9)
辅酶Q9; Ubiquinone Q9; CoQ9; Ubiquinone 9
A mitochondrial ubiquinone
GC32457 Asymmetric dimethylarginine
N5-[(二甲基氨基)亚氨基甲基]-L-鸟氨酸
An endogenous NOS inhibitor
GC32446 Vitamin K1 (Phylloquinone)
叶绿醌; Phylloquinone; Phytomenadione
A cofactor in the formation of blood-clotting proteins
GC32428 Trans-Anethole ((E)-Anethole)
茴香烯,(E)?-Anethole
A phenylpropanoid with antifungal and antioxidant activity
GC32410 5a-Pregnane-3,20-dione
氢化黄体酮
A progesterone receptor agonist and progesterone metabolite
GC32391 Pyrogallol
邻苯三酚
A natural oxidant
GC32387 Farnesol
法呢醇

An isoprenoid with diverse biological activities
GC32372 PCL 016
2-吡啶甲酸
Picolinic acid (PCL 016) is a pyridine carboxylate metabolite of tryptophan and acts as an anti-infective and immunomodulator. It acts by binding with the zinc associated with zinc finger proteins to alter their structure and inhibit function.
GC32359 Pyrrole-2-carboxylic acid
吡咯-2-羧酸
Pyrrole-2-carboxylic acid (2-Pyrrolecarboxylic acid) is a degradation product of sialic acids and a derivative of the oxidation of the D-hydroxyproline isomers by mammalian D-amino acid oxidase.
GC32294 1-Kestose
1-蔗果三糖
1-酮糖是一种在蔬菜中发现的三糖，由β-D-呋喃果糖组成，在 1 位和 2 位分别连接有 β-D-呋喃果糖和 α-D-吡喃葡萄糖残基，具有益生元和抗糖尿病活性
GC32216 Squalene (Super Squalene)
角鲨烯; Super Squalene; trans-Squalene; AddaVax
A biosynthetic precursor to steroids
GC32215 Propylparaben (Propyl parahydroxybenzoate)
羟苯丙酯; Propyl parahydroxybenzoate; Propyl 4-hydroxybenzoate
Propylparaben (Propyl 4-hydroxybenzoate, Propyl p-hydroxybenzoate, nipasol), a natural substance found in many plants and some insects, is an antimicrobial, preservative and flavouring agent.
GC32037 Cholesteryl palmitate
胆固醇棕榈酸酯
A cholesterol ester
GC32012 D-Ribose(mixture of isomers)
D-(-)-核糖
D-ribose is a naturally occurring sugar involved in producing energy in the body and is also the structural basis of DNA and RNA.
GC31853 D-Panthenol (Dexpanthenol)
D-泛醇; Dexpanthenol

D panthenol (Dexpanthenol, D-Panthenol, Pantothenol, Ilopan, D-Pantothenyl alcohol) is an alcoholic analogue of D-pantothenic acid and cholinergic agent.
GC31794 Methyl vanillate
香草酸甲酯

Methyl Vanillate, one of the ingredients in Hovenia dulcis Thunb, activates the Wnt/β-catenin pathway and induces osteoblast differentiation in vitro.
GC31725 Arachidonic acid (Immunocytophyt)
花生四烯酸; Immunocytophyt
花生四烯酸Arachidonic acid 是一种必需的不饱和脂肪酸,存在于动物和人类脂肪中,也存在于肝脏、大脑和腺体器官中。
GC31700 Tuftsin A phagocytosis-stimulating peptide
GC31672 Tetrahydrobiopterin (Sapropterin)
四氢生物蝶呤; (Rac)-Sapropterin
四氢生物蝶呤 (Sapropterin) ((Rac)-Sapropterin) 是芳香族氨基酸羟化酶的辅助因子，也是所有一氧化氮合酶 (NOS) 同种型的必需辅助因子。
GC31641 Suberylglycine
8-[(羧基甲基)氨基]-8-氧代-辛酸
A glycine-conjugated form of suberic acid
GC31640 4-(1,2-Dihydroxyethyl)benzene-1,2-diol
DL-3,4-二羟基苯基二醇
An active metabolite of norepinephrine
GC31637 Docosapentaenoic acid 22n-3
二十二碳五烯酸
Docosapentaenoic acid 22n-3 (n-3 DPA)是EPA的延长代谢产物，是二十碳五烯酸（EPA）和二十二碳六烯酸（DHA）之间的中间产物。
GC31636 Cholesteryl linoleate
胆甾烯基亚油酸酯
A cholesterol ester
GC31630 (S)-2-Hydroxy-3-phenylpropanoic acid
L-3-苯乳酸
(S)-2-Hydroxy-3-phenylpropanoic acid (L-(-)-3-Phenyllactic acid, (2S)-2-Hydroxy-3-phenylpropanoic acid) is a valuable building block in the pharmaceutical and chemical industry—has recently emerged as an important monomer in the composition of the novel degradable biocompatible material of polyphenyllactic acid.