Endogenous Metabolite(内源性代谢物)

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Products for Endogenous Metabolite

Cat.No. 产品名称 Information
GC31626 Bovinic acid
共轭(9Z11E)亚油酸,Bovinic acid; 9Z,11E-CLA; Rumenic Acid

An isomer of linoleic acid
GC31625 3-(3-Methoxyphenyl)propionic acid
3-(3-甲氧基苯基)丙酸
3-(3-Methoxyphenyl)propionic acid is a naturally occurring human metabolite, It is an organic acid and excreted in human urine.
GC31624 D-Xylulose
D-木酮糖

A ketopentose
GC31622 (S)-2-Hydroxysuccinic acid
L-苹果酸; (S)-Hydroxybutanedioic acid; (S)-E 296
(S)-2-Hydroxysuccinic acid (L-Malic acid), is a naturally occurring isomer of malic acid, found mainly in sour and unripe fruits.
GC31620 L-(-)-Fucose
L(-)岩藻糖,6-Desoxygalactose; L-(-)-Fucose; L-Galactomethylose

A monosaccharide important for immune function
GC31619 Decanedioic acid
癸二酸
Sebacic acid (1,8-Octanedicarboxylic acid) is a saturated, straight-chain naturally occurring dicarboxylic acid
GC31617 7-Methylxanthine
7-甲基黄嘌呤
An adenosine A₁ receptor antagonist and active metabolite of theobromine and caffeine
GC31612 Thiamine pyrophosphate
焦磷酸硫胺素

A metabolite of vitamin B₁
GC31611 2-Phenylpropionic acid
2-苯基丙酸
2-Phenylpropionic acid (2-Phenylpropionate, Hydratropic acid, α-methyl-α-toluic acid) is an intermediate in alpha-Methylstyrene (2-phenylpropylene) metabolism.
GC31610 1-Methyluric acid
1-甲基尿酸

1-甲基尿酸是人体三种主要的茶碱代谢物之一。1-甲基尿酸是尿路结石中的嘌呤成分之一。甲基化嘌呤来源于甲基黄嘌呤（咖啡因、茶碱和可可碱）的代谢。作用于膀胱黏膜，并能增加血糖，胰岛素，甘油三酯和胆固醇的水平。
GC31609 Glutarylcarnitine
戊二酰基肉碱

Glutarylcarnitine丙二酸尿症和I型戊二酸尿症的重要诊断代谢物。
GC31606 Docosanoic acid
二十二酸
A long-chain saturated fatty acid
GC31605 N-Isovaleroylglycine
N-异戊酰氨基乙酸
A urinary metabolite of leucine
GC31603 Delta-Tocopherol
(+)-DELTA-生育酚

A biologically active form of vitamin E
GC31602 Adrenic Acid (cis-7,10,13,16-Docosatetraenoic acid)
廿二碳四烯酸,Adrenic Acid
A naturally-occurring PUFA formed through elongation of arachidonic acid
GC31595 3-Methylbutanoic acid
异戊酸

3-Methylbutanoic acid (Isovaleric acid, Delphinic acid, 3-Methylbutyric acid, Isopentanoic acid, β-methylbutyric acid) is a natural fatty acid found in a wide variety of plants and essential oils. It has a strong pungent cheesy or sweaty smell, but its volatile esters have pleasing scents and are used widely in perfumery.
GC31594 DL-O-Phosphoserine
DL-O-磷酸丝氨酸
DL-O-Phosphoserine是人类生物流体中的正常代谢物，是丝氨酸和磷酸的酯。
GC31590 Cholestenone
胆甾烯酮; 4-Cholesten-3-one
A cholesterol metabolite
GC31588 L-Hexanoylcarnitine L-Hexanoylcarnitine是一种酰基肉碱，被发现和乳糜泻有关。
GC31587 L-Homocitrulline
高瓜氨酸
An amino acid and a product of carbamylation
GC31584 Indole-3-carboxylic acid
3-吲哚甲酸
A plant metabolite with diverse biological activities
GC31581 Pyridoxylamine
吡多胺
Pyridoxylamine是糖基化终产物(AGE)和脂质化终产物(ALE)抑制剂，可防止糖尿病引起的视网膜血管病变。
GC31576 Glycodeoxycholate Sodium (Sodium glycyldeoxycholate)
脱氧甘胆酸钠,Sodium glycyldeoxycholate
Glycochenodeoxycholic acid (GCDC, Glycodeoxycholate, Deoxycholylglycine) is a bile salt that is used as an anionic detergent to solubilize lipids.
GC31575 Porphobilinogen
紫質膽素原
Porphobilinogen可以作为一种光毒素，神经毒素和代谢毒素。
GC31574 Undecanedioic acid
十一烷二酸
Undecanedioic acid (1,9-Nonanedicarboxylic acid, Undecanedionate) is a long-chain dicarboxylic acid that has applications in corrosion inhibitors, hot melt adhesives, high performance polyamides/Nylon, and more.
GC31572 Octanedioic acid
辛二酸,Octanedioic acid

Octanedioic acid (Suberic acid) is a dicarboxylic acid used in drug syntheses and plastics manufacture.
GC31571 Isomaltose (6-O-α-D-Glucopyranosyl-D-glucose)
异麦芽糖; 6-O-α-D-Glucopyranosyl-D-glucose; D-Isomaltose

A natural disaccharide
GC31570 Tiglyl carnitine Tiglylcarnitine被发现和乳糜泻，线粒体乙酰辅酶A硫代酶(T2)缺乏症有关。
GC31569 3-Amino-2-methylpropanoic acid
3-氨基异丁酸
3-Aminoisobutyric acid (3-Amino-2-methylpropanoic acid, 3-Aminoisobutyrate, β-aminoisobutyric acid) is a product formed by the catabolism of thymine.
GC31562 Guanylic acid (5'-GMP)
鸟苷酸; 5'-GMP; 5'-guanosine monophosphate

鸟苷酸 (5'-GMP) (5'-GMP) 涉及多种代谢紊乱，包括 AICA-核糖苷尿途径、腺苷脱氨酶缺乏症、腺嘌呤磷酸核糖基转移酶缺乏症 (aprt) 和 2-羟基戊二酸尿症途径。
GC31559 Thymine
胸腺嘧啶

Thymine (5-methyluracil) is one of the four nucleobases in the nucleic acid of DNA.
GC31553 3b-Hydroxy-5-cholenoic acid
3B-羟基-D5-胆烯酸
A bile acid
GC31549 Glycolic acid
乙醇酸
Glycolic acid (dicarbonous acid, hydroxyacetic acid, hydroacetic acid) is the smallest alpha-hydroxy acid. Due to its excellent capability to penetrate skin, glycolic acid is often used in skin care products, most often as a chemical peel. Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour.
GC31546 3-Methyladipic acid
3-甲基己二酸
A catabolite of phytanic acid
GC31544 2-Hydroxy-2-methylbutanoic acid
2-羟基-2-甲基丁酸
2-Hydroxy-2-methylbutyric acid is an unusual metabolite found in the urine of patients with 2-hydroxyglutaric aciduria and maple syrup urine disease. 2-Hydroxy-2-methylbutyric acid is also a secondary metabolite found in human urine after exposure to the gasoline additive tert-amyl-Me-ether (TAME).
GC31540 Methionine sulfoxide
DL-蛋氨酸亚砜

Methioninesulfoxide是一种具有活性氧的甲硫氨酸的氧化产物，可被当做体内氧化应激的生物标记。
GC31539 D-Gluconic acid solution
葡萄糖酸; 葡萄糖醛酸

D-Gluconic acid is an antifungal agent.
GC31536 N-Oleoyl glycine
A putative substrate for peptidyl glycine α-amidating enzyme
GC31535 3-Methyl-L-histidine
3-甲基-L-组氨酸
An amino acid
GC31524 Glycylglycine
双甘肽

Glycylglycine (Diglycine, Diglycocoll, Glycine dipeptide), the simplest peptide made of two glycine molecules, is usually used in the synthesis of more complicated peptides.
GC31493 Galactose 1-phosphate Potassium salt
阿尔法-D-半乳糖1-磷酸二钾盐五水合物
An intermediate in the interconversion of glucose and galactose
GC31438 Maltotetraose (Amylotetraose)
麦芽四糖; Amylotetraose; Fujioligo 450; α-1,4-Tetraglucose
A tetrasaccharide
GC31435 2-Methylsuccinic acid
甲基丁二酸

2-Methylsuccinic acid (Pyrotartaric acid, 2-methylbutanedioic acid, propane-1,2-dicarboxylic acid, Methylsuccinate) is a normal metabolite found in human fluids.
GC31428 H-Gly-Pro-OH
甘油-L-脯氨酸

H-Gly-Pro-OH (Glycyl proline, Glycyl-L-proline) is a dipeptide composed of glycine and proline, and is an end product of collagen metabolism that is further cleaved by prolidase. The resulting proline molecules are recycled into collagen or other proteins.
GC31423 Dodecanoylcarnitine Dodecanoylcarnitine和脂肪酸氧化紊乱有关，如长链酰基辅酶脱氢酶缺乏症、肉毒棕榈酰基转移酶I/II缺乏症，也和乳糜泻有关。
GC31420 all-trans-4-Oxoretinoic acid (all-trans 4-Keto Retinoic Acid)
4-KETO全反式维甲酸,all-trans 4-Keto Retinoic Acid
An active metabolite of all-trans retinoic acid
GC31419 L-Gulono-1,4-lactone
L-古洛糖酸-γ-内酯
L-Gulono-1,4-lactone (L-Gulonolactone, L-Gulono-gamma-lactone, reduced ascorbic acid) is the substrate of the enzyme L-gulono-1,4-lactone oxidoreductase, which catalyzes the last step of the biosynthesis of L-ascorbic acid (vitamin C) in plants and animals.
GC31403 H-HoPro-OH
L-2-哌啶酸,H-HoPro-OH
L(-)-Pipecolinic acid (L-Homoproline) is a normal human metabolite present in human blood.
GC31401 Cholesteryl behenate (Cholesteryl docosanoate)
胆固醇山萮酸酯; Cholesteryl docosanoate; Cholesterol behenate

A cholesterol ester
GC31398 Stearic acid
硬脂酸
A long-chain saturated fatty acid