Maltotetraose (Amylotetraose)
(Synonyms: 麦芽四糖; Amylotetraose; Fujioligo 450; α-1,4-Tetraglucose) 目录号 : GC31438
A tetrasaccharide
Cas No.:34612-38-9
Sample solution is provided at 25 µL, 10mM.
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Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Maltotetraose is a tetrasaccharide that is composed of glucose molecules linked by α-1,4 glycosidic bonds and has been found in B. stearothermophilus.1,2,3,4 It increases the α-amylase synthesis rate in B. stearothermophilus 3-fold greater than sucrose or glucose when used at a concentration of 0.1 mM.2 Maltotetraose (750 μg/ml) inhibits the growth of E. carotovora in a cylinder-agar plate assay but does not affect the growth of several other microorganisms.4 It also inhibits TNF-α-induced expression of intercellular adhesion molecule-1 (ICAM-1) in MOVAS-1 mouse smooth muscle cells (VSMCs) transfected with an ICAM-1 luciferase reporter when used at a concentration of 20 μM.5
1.Sauer, J., Sigurskjold, B.W., Christensen, U., et al.Glucoamylase: Structure/function relationships, and protein engineeringBiochim. Biophys. Acta1543(2)275-293(2000) 2.Welker, N.E., and Campbell, L.L.Induction of α-amylase of Bacillus stearothermophilus by maltodextrinsJ. Bacteriol.86(4)687-691(1963) 3.Fujita, M., Torigoe, K., Nakada, T., et al.Cloning and nucleotide sequence of the gene (amyP) for maltotetraose-forming amylase from Pseudomonas stutzeri MO-19J. Bacteriol.171(3)1333-1339(1989) 4.Kondo, H., Honke, T., Hasegawa, R., et al.Isolation of maltotetraose from Streptomyces as an antibiotic against Erwinia carotovoraJ. Antibiot. (Tokyo)28(2)157-160(1975) 5.Shin, S.Y., Jung, Y.J., Yong, Y., et al.Inhibition of PDGF-induced migration and TNF-α-induced ICAM-1 expression by maltotetraose from bamboo stem extract (BSE) in mouse vascular smooth muscle cellsMol. Nutr. Food Res.60(9)2086-2097(2016)
| Cas No. | 34612-38-9 | SDF | |
| 别名 | 麦芽四糖; Amylotetraose; Fujioligo 450; α-1,4-Tetraglucose | ||
| Canonical SMILES | OC[C@@H](O[C@H](O[C@@]([C@H](O)CO)([H])[C@H](O)[C@@H](O)C=O)[C@H](O)[C@H]1O)[C@@]1([H])O[C@H]2O[C@@H]([C@@H](O[C@@]3([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)CO)[C@H](O)[C@H]2O)CO | ||
| 分子式 | C24H42O21 | 分子量 | 666.58 |
| 溶解度 | Water: 250 mg/mL (375.05 mM) | 储存条件 | Store at -20°C |
| General tips | 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 储备液的保存方式和期限：-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。 为了提高溶解度，请将管子加热至37℃，然后在超声波浴中震荡一段时间。 |
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| Shipping Condition | 评估样品解决方案：配备蓝冰进行发货。所有其他可用尺寸：配备RT，或根据请求配备蓝冰。 | ||
| 制备储备液 | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 1.5002 mL | 7.501 mL | 15.002 mL |
| 5 mM | 0.3 mL | 1.5002 mL | 3.0004 mL |
| 10 mM | 0.15 mL | 0.7501 mL | 1.5002 mL |
| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % saline | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL saline，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。