Endogenous Metabolite(内源性代谢物)

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Products for Endogenous Metabolite

Cat.No. 产品名称 Information
GC33762 Deoxycholic acid (Cholanoic Acid)
去氧胆酸; Cholanoic Acid; Desoxycholic acid
Deoxycholic acid (Cholanoic Acid)是一种胆汁酸，肠道代谢副产物，可以激活G 蛋白偶联胆汁酸受体TGR5。
GC33748 Ethylmalonic acid
乙基丙二酸
Ethylmalonicacid是一种非致癌性的潜在有毒物质，与神经性厌食和甲氧基脱羧酶缺乏症有关。
GC33746 Dehydroascorbic acid
脱氢抗坏血酸
An oxidized form of ascorbic acid
GC33742 2-Hydroxyphenylacetic acid
邻羟基苯乙酸
2-Hydroxyphenylacetic acid (2-Hydroxybenzeneacetate, ortho-Hydroxyphenylacetic acid) is a substrate of the enzyme oxidoreductases in the pathway styrene degradation.
GC33739 3-Methoxytyramine (3-O-methyl Dopamine)
4-(2-氨基乙基)-2-甲氧基苯酚,3-O-methyl Dopamine
3-Methoxytyramine (3-O-methyl Dopamine) 是一种众所周知的 3-羟基酪胺/多巴胺的细胞外代谢物，是一种神经调节剂。
GC33738 3-Methoxytyramine hydrochloride (3-O-methyl Dopamine hydrochloride)
2-甲氧基-4-(2-氨基乙基)苯酚,3-O-methyl Dopamine hydrochloride
A natural metabolite of dopamine
GC33704 6-Hydroxymelatonin
苏达灭
An active metabolite of melatonin
GC33703 3,4,5-Trimethoxycinnamic acid
3,4,5-三甲氧基肉桂酸
3,4,5-Trimethoxycinnamic acid (TMCA) is one of the constituents of Polygalae Radix and may exert anti-seizure activity by acting at the GABAA/BZ receptor complex.
GC33698 5-Hydroxyindole-3-acetic acid
5-羟基吲哚-3-乙酸
A metabolite of serotonin
GC33687 Glycoursodeoxycholic acid (Ursodeoxycholylglycine)
甘氨熊胆酸,Ursodeoxycholylglycine
A glycine-conjugated form of ursodeoxycholic acid
GC33661 Pseudouridine
假尿苷
The C-5 glycoside isomer of uridine
GC33660 Dulcite (Dulcitol)
甜醇; Dulcitol; Melampyrit; NSC 1944
A reduced form of galactose
GC33659 Indolelactic acid
3-吲哚乳酸,Indole-3-lactic acid
Indolelactic acid（Indole-3-lactic acid）是一种由色氨酸衍生的微生物代谢物，主要由肠道菌群产生。它作为信号分子参与调节宿主免疫反应和维持肠道稳态，具有抗炎特性，并在代谢通路和肠-脑轴通讯中发挥重要作用。
GC33656 4-Hydroxy-3-methylbenzoic acid
4-羟基-3-甲基苯甲酸
4-Hydroxy-3-methylbenzoic acid is a normal organic acid identified in urine specimens from a healthy population.
GC33653 3-Methoxybenzoic acid (3-Anisic acid)
3-甲氧基苯甲酸,3-Anisic acid; 3-Methoxybenzoic acid; NSC 27014; NSC 9264; m-Methoxybenzoic acid
3-Methoxybenzoic acid (m-Anisic acid, 3-Methoxybenzoate, 3-Anisic acid, m-Methylsalicylic acid) is a food additive that acts as a flavouring ingredient.
GC33651 Imidazoleacetic acid
咪唑-4-乙酸,Imidazolyl-4-acetic acid
Imidazoleaceticacid是刺激咪唑受体(imidazolereceptors)的内源性配体。
GC33650 5,6-Dihydrouracil
二氢尿嘧啶; 5,6-Dihydrouracil
A catabolite of uracil
GC33649 3,4-Dihydroxybenzeneacetic acid
3,4-二羟基苯乙酸
A dopamine metabolite
GC33648 Taurocholic acid (N-Choloyltaurine)
牛磺胆酸; N-Choloyltaurine
A quantitative analytical standard guaranteed to meet MaxSpec^? identity, purity, stability, and concentration specifications
GC33646 1-Methyladenine
1-甲基腺嘌呤
1-甲基腺嘌呤是在N-1位被甲基取代的腺嘌呤，是 DNA 烷基化损伤的产物，可通过氧化去甲基化损伤逆转进行修复。
GC33645 2-Guanidinoacetic acid
胍基乙酸,Guanidinoacetic acid
A metabolite of glycine and precursor in the biosynthesis of creatine
GC33643 2,6-Dimethoxybenzoic acid
2,6-二甲氧基苯甲酸
2,6-Dimethoxybenzoic acid is a polyphenol compound found in foods of plant origin.
GC33642 2,6-Dihydroxybenzoic acid
2,6-二羟基苯甲酸
2,6-Dihydroxybenzoic acid (γ-resorcylic acid, 2-Carboxyresorcinol, 2,6-Resorcylic acid) is a phenolic compound which is known to have poor biological performance such as DPPH scavenging activity and microbial growth inhibition.
GC33641 Hydroxyphenylacetylglycine
2-[2-(4-羟基苯基)乙酰氨基]乙酸
A metabolite of tyramine
GC33640 Nepsilon-Acetyl-L-lysine
N-EPSILON-乙酰-L-赖胺基乙酸
Nepsilon-Acetyl-L-lysine is an R-chain N-acetylated α amino acid used together with other lysine analogues to differentiate and characterized various aminoacylases and regulator 2 (Sir2) enzymes/sirtuins.
GC33637 2,5-Furandicarboxylic acid
2,5-呋喃二甲酸
2,5-Furandicarboxylic acid (Dehydromucic acid) is a normal urinary metabolite in humans and an important renewable building block because of its potential as a substitute for a variety of petrochemicals, such as terephthalic acid and adipic acid.
GC33636 5'-Deoxyadenosine
5-脱氧腺嘌呤核苷
An adenosine analog
GC33635 N-Methylsarcosine (DMG)
N,N-二甲基甘氨酸; Dimethylglycine; DMG; N,N-Dimethylglycine
N-Methylsarcosine (N,N-Dimethylglycine, (Dimethylamino)acetic acid) is a natural N-methylated glycine that is used in the development of glycine-based ionic liquids and emulsifiers.
GC33633 2-(2-Methylbenzamido)acetic acid
2-甲基马尿酸
A metabolite of xylene
GC33631 3-Chloro-L-tyrosine
3-氯-L-酪氨酸
A derivative of L-tyrosine
GC33630 Tryptamine
色胺
An indole alkaloid
GC33629 DPPC (129Y83)
二棕榈酰磷脂酰胆碱; 129Y83
DPPC (129Y83)是一种磷酸甘油酯，可用于制备脂质体。
GC33626 2,4-Dihydroxybenzoic acid
2,4-二羟基苯甲酸
2,4-Dihydroxybenzoic acid (β-resorcylic acid, p-Hydroxysalicylic acid) is a degradation product of cyanidin glycosides from tart cherries in cell cultures and a metabolite found in human plasma after cranberry juice consumption.
GC33625 N8-Acetylspermidine dihydrochloride
N8-乙酰基亚精胺二盐酸盐
An endogenous polyamine
GC33622 2',4'-Dihydroxyacetophenone
2,4-二羟基苯乙酮,Resacetophenone; 1-?(2,?4-?Dihydroxyphenyl)?ethanone
2,4-Dihydroxyacetophenone (Resacetophenone, 4-Acetylresorcinol) is a plant metabolite that can act as a qualitative reagent for ferric iron.
GC33621 1,2-Dipalmitoyl-sn-glycerol 3-phosphate
1,2-二棕榈酰磷脂酸
1,2-Dipalmitoyl-sn-glycerol3-phosphate是一种磷脂酸。
GC33618 3-(3,4,5-Trimethoxyphenyl)propanoic acid
3-(3,4,5-三甲氧基苯基)丙酸
3-(3,4,5-Trimethoxyphenyl)propanoicacid存在于草药和香料中。3-(3,4,5-Trimethoxyphenyl)propanoicacid是Piperlongum(长胡椒)和Piperretrofractum(爪哇长胡椒)的成分。
GC33617 Hexacosanoic acid
蜡酸
A 26-carbon saturated fatty acid
GC33616 7-Methylguanine
7-甲基鸟嘌呤
A nucleotide metabolite
GC33615 3,4-Dimethoxyphenylacetic acid
3,4-二甲氧基苯乙酸
Homoveratrumic acid (Homoveratric acid) is the main metabolite of 3,4-dimethoxyphenylethylamine (DMPEA) in urine.
GC33613 5-Hydroxymethyluracil
5-羟甲基脲嘧啶
Product of oxidative damage to DNA
GC33612 N-Acetyl-L-aspartic acid
N-乙酰-L-天门冬氨酸
An acetylated form of L-aspartic acid
GC33610 4-Hydroxycyclohexanecarboxylic acid
4-羟基环己烷甲酸
4-Hydroxycyclohexanecarboxylicacid属于环己醇有机化合物类。
GC33608 Malic acid (E 296)
DL-苹果酸; Hydroxybutanedioic acid; E 296
The racemate of L-malic acid
GC33607 Hydrocinnamic acid (3-Phenyl-n-propionic acid)
3-苯丙酸; 3-Phenylpropionic acid; 3-Phenylpropanoic acid; 3-Phenyl-n-propionic acid
Hydrocinnamic acid (3-phenylpropionic acid, Benzylacetic acid) is a substrate of the enzyme oxidoreductases in the pathway phenylalanine metabolism (KEGG). It is an antifungal agent and a metabolite.
GC33606 D-(+)-Glucono-1,5-lactone (Gluconic acid lactone)
葡萄糖酸内酯,Gluconic acid lactone
Gluconolactone is a naturally occurring polyhydroxy acid with metal chelating, moisturizing and antioxidant activity.
GC33605 2'-Deoxyadenosine monohydrate
2'-脱氧腺苷一水合物
A deoxyribonucleoside
GC33604 3-Pyridineacetic acid
3-吡啶乙酸
3-Pyridineaceticacid是尼克酸的高同系物，是尼古丁（和其它烟草生物碱）的分解产物。
GC33603 Dihydrofolic acid
二氢叶酸
An active metabolite of folic acid
GC33602 Decanoic acid
癸酸
Capric acid (DA, Decanoic acid, Decylic acid), a component of medium-chain triclycerides occurring naturally in coconut oil and palm kernel oil, contributes to seizure control through direct AMPA receptor inhibition. Capric acid is also a modulating ligand for PPARs. Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt.