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Home >> Signaling Pathways >> Proteases >> Endogenous Metabolite

Endogenous Metabolite(内源性代谢物)

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Products for  Endogenous Metabolite

  1. Cat.No. 产品名称 Information
  2. GC30593 3-Methyl-2-oxovaleric acid

    3-甲基-2-氧基戊酸

     3-Methyl-2-oxovalericacid是一种神经毒素，一种酸性原和一种代谢毒素，它是由支链氨基酸不完整分解产生的异常的代谢物。
  3. GC30588 Protirelin (Synthetic thyrotropin-releasing factor)

    普罗瑞林; Thyrotropin-releasing-hormone; TRH

    A tropic hormone
  4. GC30586 (±) Anabasine

    八角枫碱

     (±)Anabasine是一种肌肉松弛剂，可用于外科手术时肌肉松驰。
  5. GC30472 Dehydrocholate sodium (Sodium dehydrocholate)

    去氢胆酸钠,Sodium dehydrocholate

     Sodium Dehydrocholate is a semisynthetic bile acid made from cholic acid. It has been used for stimulation of biliary lipid secretion.
  6. GC30465 L-Carnosine

    肌肽; L-肌肽

     A dipeptide with diverse biological activities
  7. GC30449 Fumaric acid

    反丁烯二酸

     Fumaric acid (Fumarate, 2-Butenedioic acid, Trans-Butenedioic acid) is an intermediate in the citric acid cycle used by cells to produce energy in the form of adenosine triphosphate (ATP) from food; also a product of the urea cycle.
  8. GC30395 DL-Panthenol (DL-Pantothenol)

    DL-泛醇; DL-Pantothenol; DL-Pantothenyl alcohol

     DL-panthenol (DL-Pantothenol, DL-Pantothenyl alcohol) is a racemic mixture of D and L form of panthenol,a provitamin of B5.
  9. GC30370 Dinoprost (Prostaglandin F2a)

    地诺前列素; Prostaglandin F2α; PGF2α

     Dinoprost (Prostaglandin F2a)是一种口服有效的强效前列腺素受体 （FP 受体） 激动剂。Dinoprost刺激子宫肌层活动，放松宫颈，抑制黄体类固醇生成，并通过直接作用诱导黄体溶解。
  10. GC30354 D-Pipecolinic acid

    D-哌啶酸

     D-Pipecolinicacid是人体液中的一种代谢物。
  11. GC30353 3-Oxopentanedioic acid

    1,3-丙酮二羧酸

     3-Oxopentanedioic acid (1,3-Acetonedicarboxylic acid; 3-Oxoglutaric acid) is an intermediate for organic compound synthesis.
  12. GC30343 Selenomethionine (Seleno-DL-methionine)

    硒代蛋氨酸; Seleno-DL-methionine; DL-Selenomethionine

    硒代蛋氨酸（Seleno-DL-methionine）是一种天然存在的含硒氨基酸，是硒的常见天然食物来源。
  13. GC30337 Galactose 1-phosphate

    半乳糖-1-磷酸

     半乳糖1磷酸是半乳糖-1-磷酸尿苷酰转移酶(GALT)的作用底物,具有细胞毒性,对糖代谢途径中的多种酶有抑制作用.Gal-1-P(1- 16mm;37℃;1h)能刺激大鼠脑Na+,K+-ATP酶。
  14. GC30334 NCX 1000 NCX1000是一种肝特异性NO供体，它来源于熊去氧胆酸。
  15. GC30333 Valerylcarnitine

    Valerylcarnitine是一种内源性代谢物，属于短链酰基肉碱。
  16. GC30332 Isovalerylcarnitine

    (3R)-3-(3-甲基丁酰氧基)-4-(三甲基铵)丁酸内盐

     Isovalerylcarnitine是L-亮氨酸分解代谢的产物。它增加了钙蛋白酶的活性。
  17. GC30329 Stearoylcarnitine Stearoylcarnitine是一种脂肪酸酯脂质分子。
  18. GC30324 Mevalonic acid

    3,5-二羟基-3-甲基戊酸,MVA

     甲羟戊酸是从头生物合成途径中胆固醇的前体。
  19. GC30316 L-Cystathionine

    L-胱硫醚

    An intermediate in cysteine synthesis
  20. GC30304 (S)-3-Hydroxybutanoic acid ((S)-β-Hydroxybutanoic acid)

    (S)-3-羟基丁酸,(S)-β-Hydroxybutanoic acid; L-(+)-3-Hydroxybutyric acid; L-β-Hydroxybutyric acid

    (S)-3-Hydroxybutanoic acid ((S)-β-Hydroxybutanoic acid) 是一种正常的人体代谢物，已发现在缓解抑郁症的老年患者中升高。
  21. GC30301 Turanose

    松二糖

     Turanose是一种还原性二糖。
  22. GC30298 Butyrylcarnitine

    丁酰肉碱

     Butyrylcarnitine是血浆中的代谢物，是异常脂质和能量代谢的指标，来改善心脏衰竭的诊断和预后。
  23. GC30281 Pyrithioxin (Pyritinol)

    吡硫醇; Pyritinol; Pyridoxine disulfide; Vitamin B6 disulfide

     Pyrithioxin (Bonifen, Encefabol, Pyritinol, Vitamin B6 disulfide) is a neurotropic agent which reduces permeability of blood-brain barrier to phosphate. It has no vitamin B6 activity.
  24. GC30278 Cholesteryl oleate

    胆固醇油酸酯

    A cholesterol ester
  25. GC30268 Maltopentaose (Maltopentose)

    麦芽五糖; Maltopentose

     Maltopentaose (Maltopentose)是一种由五个葡萄糖单元通过α-1,4-糖苷键连接而成的寡糖。Maltopentaose是麦芽糊精中最短的低聚糖，能够用于研究α-乳清蛋白的糖化和磷酸化。
  26. GC30266 L-SelenoMethionine

    L-硒代蛋氨酸

     A naturally occurring amino acid with antioxidant properties
  27. GC30263 Glucosamine (D-Glucosamine)

    氨基葡萄糖; D-Glucosamine; Chitosamine

     Glucosamine (2-amino-2-deoxy-D-glucose) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. It is commonly used as a treatment for osteoarthritis. Glucosamine（GS） treatment selectively downregulates HIF-1α at the protein level in YD-8 cells via interference of production of the citric acid cycle metabolites.
  28. GC30258 Menaquinone-4 (Vitamin K2)

    四烯甲萘醌,Vitamin K2(MK-4); Menaquinone K4

     A homolog of of vitamin K2
  29. GC30219 Azelaic acid (Nonanedioic acid)

    壬二酸; Nonanedioic acid

     A dicarboxylic acid with diverse biological activities
  30. GC30215 Linoleic acid

    亚油酸

    An essential ω-6 PUFA
  31. GC30214 Pyruvic aldehyde (~40% in water)

    丙酮醛

    Pyruvicaldehyde常被用作有机合成中的一种试剂，一种调味剂以及在鞣革中的应用。
  32. GC30210 (R)-3-Hydroxybutanoic acid

    (R)-3-羟基丁酸,(R)-(-)-3-Hydroxybutanoic acid; (R)-3-Hydroxybutyric acid

     (R)-3-Hydroxybutanoic acid是一种聚羟基丁酸酯（PHB）单体，能够通过与各种羟基脂肪酸反应制备共聚物，具有工业和医药用途。
  33. GC30196 Maltose monohydrate

    麦芽糖-水合物

     A disaccharide
  34. GC30192 Pyruvic acid (2-Oxopropanoic acid)

    丙酮酸; Acetylformic acid

     Pyruvic acid (Acetylformic acid) is an important organic chemical intermediate that plays a role in cardiomyocyte pathophysiology and therapy. Pyruvic acid markedly increases the level of lactate dehydrogenase (LDH) and creatine kinase (CK) and reduces the level of Ca2+Mg2+-ATPase and Na+K+-ATPase.
  35. GC30189 5-Hydroxymethyl-2-furancarboxylic acid

    5-羟甲基-2-呋喃甲酸

     A major metabolite of 5-hydroxymethyl-2-furfural
  36. GC30187 γ-Glu-Phe (γ-Glutamylphenylalanine)

    γ-Glutamylphenylalanine

     γ-Glu-Phe (γ-Glutamylphenylalanine) (γ-Glutamylphenylalanine) 由解淀粉芽孢杆菌 (GBA) 和米曲霉 (GAO) 合成。
  37. GC30166 Coproporphyrin III (Zincphyrin)

    粪卟啉二盐酸盐,Zincphyrin

     粪卟啉 III (Zincphyrin) (Zincphyrin) 是一种天然存在的卟啉衍生物，主要存在于尿液中。
  38. GC30165 Perillartine (DL-Perillartine)

    紫苏葶,DL-Perillartine

     Perillartine (Perilla sugar, Peryllartine) is a sweetener. Perillartine can activation of the Tas1r2 monomeric receptors of human, rhesus monkey and squirrel monkey but not mouse in a species-dependent manner.
  39. GC30148 (S)-b-aminoisobutyric acid

    L-3-氨基异丁酸

     (S)-b-aminoisobutyricacid是源自胸腺嘧啶和缬氨酸分解代谢的非蛋白质氨基酸。
  40. GC30146 3,4-Dihydroxymandelic acid

    3,4-二羟基扁桃酸

     3,4-Dihydroxymandelicacid是去甲肾上腺素的代谢产物。
  41. GC30136 2-Ketoglutaric acid

    α-酮戊二酸; Alpha-Ketoglutaric acid

     An intermediate in the citric acid cycle
  42. GC30131 Leucyl-phenylalanine Leucyl-phenylalanine是二肽的有机化合物。
  43. GC30110 Oleic acid (9-cis-Octadecenoic acid)

    油酸; 9-cis-Octadecenoic acid; 9Z-Octadecenoic acid

     油酸（9-顺式-十八碳烯酸）是一种单不饱和的Omega-9脂肪酸，存在于植物和动物中。
  44. GC30103 Lecithin

    卵磷脂

     A sphingolipid
  45. GC30048 Pantethine (D-Pantethine)

    泛硫乙胺; D-Pantethine; LBF disulfide

     Pantethine (Bis-pantethine, Pantetina, Pantomin, Pantosin) is a naturally occurring compound synthesized in the body from pantothenic acid (vitamin B5) via addition of cysteamine and used as a dietary supplement for lowering blood cholesterol and triglycerides.
  46. GC30044 L-Ornithine ((S)-2,5-Diaminopentanoic acid)

    鸟氨酸

     L-ornithine ((S)-2,5-Diaminopentanoic acid)是一种天然存在的非蛋白质氨基酸，在人体的尿素循环中发挥重要作用。
  47. GC19478 Estetrol

    雌四醇

     A naturally occurring estrogen
  48. GC19477 Lanosterol

    羊毛甾醇

     A naturally-occurring sterol
  49. GC11139 1-Stearoyl-2-Arachidonoyl-sn-glycero-3-PC

    L-α-磷脂酰胆碱-β-花生四烯酰-γ-硬脂酰,SAPC

     A phospholipid
  50. GC19444 (±)20-HDHA

    (±)20-HDoHE

     An autoxidation product of DHA and potential marker of oxidative stress
  51. GC19439 Nudifloramide

    1-甲基-6-氧代吡啶-3-甲酰胺,2PY

     A metabolite of niacin via nicotinamide

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