Acetazolamide sodium
(Synonyms: 乙酰唑胺钠) 目录号 : GC65612An Analytical Reference Standard
Sample solution is provided at 25 µL, 10mM.
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Acetazolamide is an analytical reference standard categorized as a diuretic.1 Diuretics, including acetazolamide, have been abused as performance-enhancing drugs and masking agents in sports doping.2 This product is intended for research and forensic applications.
1.Low, E.V., Avery, A.J., Gupta, V., et al.Identifying the lowest effective dose of acetazolamide for the prophylaxis of acute mountain sickness: Systematic review and meta-analysisB.M.J.345e6779(2012) 2.Cadwallader, A.B., de la Torre, X., Tieri, A., et al.The abuse of diuretics as performance-enhancing drugs and masking agents in sport doping: Pharmacology, toxicology and analysisBr. J. Pharmacol.161(1)1-16(2010)
| Cas No. | 1424-27-7 | SDF | Download SDF |
| 别名 | 乙酰唑胺钠 | ||
| 分子式 | C4H6N4NaO3S2 | 分子量 | 245.24 |
| 溶解度 | DMSO : 100 mg/mL (407.76 mM; Need ultrasonic) | 储存条件 | 4°C, away from moisture |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. | ||
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
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| 第一步：请输入基本实验信息（考虑到实验过程中的损耗，建议多配一只动物的药量） | ||||||||||
| 给药剂量 | mg/kg |  |
动物平均体重 | g | |
每只动物给药体积 | ul | |
动物数量 | 只 |
| 第二步：请输入动物体内配方组成（配方适用于不溶于水的药物；不同批次药物配方比例不同，请联系GLPBIO为您提供正确的澄清溶液配方） | ||||||||||
| % DMSO % % Tween 80 % ddH2O | ||||||||||
| 计算重置 | ||||||||||
计算结果:
工作液浓度： mg/ml；
DMSO母液配制方法： mg 药物溶于 μL DMSO溶液（母液浓度 mg/mL，
体内配方配制方法：取 μL DMSO母液，加入 μL PEG300，混匀澄清后加入μL Tween 80，混匀澄清后加入 μL ddH2O，混匀澄清。
1. 首先保证母液是澄清的；
2.
一定要按照顺序依次将溶剂加入，进行下一步操作之前必须保证上一步操作得到的是澄清的溶液，可采用涡旋、超声或水浴加热等物理方法助溶。
3. 以上所有助溶剂都可在 GlpBio 网站选购。