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6-Hydroxydopamine hydrobromide 目录号 GC16267

neurotoxin that destroys dopaminergic and noradrenergic (catecholaminergic) neurons

规格 价格 库存 购买数量
50mg
¥567.00
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Sample solution is provided at 25 µL, 10mM.

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Chemical Properties

Cas No. 636-00-0 SDF
化学名 5-(2-aminoethyl)benzene-1,2,4-triol hydrobromide
Canonical SMILES OC(C(CCN)=C1)=CC(O)=C1O.Br
分子式 C8H11NO3.HBr 分子量 250.09
溶解度 ≥25mg/mL in DMSO with ultrasonic 储存条件 Desiccate at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

产品描述

Oxidopamine hydrobromide (6-OHDA hydrobromide), an antagonist of the neurotransmitter dopamine, is a widely used neurotoxin that selectively destroys dopaminergic neurons.

References:
[1]. Fujita H et al. Cell-permeable cAMP analog suppresses 6-hydroxydopamine-induced apoptosis in PC12 cells through the activation of the Akt pathway. Brain Res. 2006 Oct 3;1113(1):10-23.
[2]. Soto-Otero R et al. Autoxidation and neurotoxicity of 6-hydroxydopamine in the presence of some antioxidants: potential implication in relation to the pathogenesis of Parkinson's disease. J Neurochem. 2000 Apr;74(4):1605-12.