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Home >> Signaling Pathways >> Microbiology & Virology >> HIV

HIV(人类免疫缺陷病毒)

HIV (human immunodeficiency virus) is a lentivirus that infect immune system. It cause immune system failure and lead to AIDS (acquired immnudeficiency syndrome).

Products for  HIV

  1. Cat.No. 产品名称 Information
  2. GC49646 Aurothioglucose (hydrate) A TrxR inhibitor
  3. GC63646 Formycin A Formycin A (NSC 102811) 是一种嘌呤核苷抗生素，一种有效的人类免疫缺陷病毒 1 型 (HIV-1) 的抑制剂，EC50 为 10 μM。Formycin A 显示抗肿瘤和抗病毒活性。
  4. GC63523 Reverse transcriptase-IN-1 Reverse transcriptase-IN-1 (Compound 12z)，二芳基苯并嘧啶 (DABP) 类似物， 是一种有效的，具有口服活性的 HIV-1 非核苷逆转录酶抑制剂。Reverse transcriptase-IN-1 具有抗病毒活性，对 HIV-1 IIIB，E138K 和 K103N 突变体的 EC50 值分别为 3.4 nM，4.3 nM 和 3.6 nM，而且对 HIV-1 逆转录酶的 IC50 值为 13.7 nM。
  5. GC63302 PMEDAP PMEDAP 是人类免疫缺陷病毒 (HIV) 复制的有效抑制剂。PMEDAP 具有抗小鼠巨细胞病毒 (MCMV) 活性。PMEDAP 是莫罗尼鼠肉瘤病毒 (MSV) 诱导的肿瘤形成和相关死亡率的有效抑制剂。
  6. GC63095 Nandrolone decanoate An Analytical Reference Standard
  7. GC62842 Amylmetacresol Amylmetacresol is an antiseptic used to treat infections of the mouth and throat.
  8. GC49441 Plerixafor (hydrochloride hydrate) An antagonist of CXCR4
  9. GC49388 N-Butyldeoxynojirimycin-d9 (hydrochloride) An internal standard for the quantification of N-butyldeoxynojirimycin
  10. GC49289 Dolutegravir O-β-D-Glucuronide A metabolite of dolutegravir
  11. GC49288 Dolutegravir M1 A metabolite of dolutegravir
  12. GC49229 Ganodermanontriol A triterpene with diverse biological activities
  13. GC49122 3′-deoxy Thymidine An antiviral nucleoside analog
  14. GC49073 Oxanosine A guanosine analog with diverse biological activities
  15. GC49040 Benanomicin B (formate) A microbial metabolite with antifungal, fungicidal, and antiviral activities
  16. GC49038 Benanomicin A A microbial metabolite with antifungal, fungicidal, and antiviral activities
  17. GC49027 Hexamethylene bisacetamide A tumor cell-differentiating agent
  18. GC49022 Didanosine-d2 An internal standard for the quantification of didanosine
  19. GC62610 Aplaviroc hydrochloride Aplaviroc (AK 602) hydrochloride，SDP的一个衍生物，是 CCR5 的拮抗剂，其对 HIV-1Ba-L， HIV-1JRFL 和 HIV-1MOKW 的 IC50 值为 0.1-0.4 nM。
  20. GC62607 EFdA-TP tetraammonium EFdA-TP tetraammonium 是一种有效的核苷逆转录酶 (RT) 抑制剂。EFdA-TP tetraammonium 作为有效的立即或延迟链终止剂 (ICT 或 DCT) 抑制 RT 催化的 DNA 合成。EFdA-TP tetraammonium 通过多种机制抑制 HIV-1 RT。
  21. GC62295 Elsulfavirine Elsulfavirine (Elpida, VM-1500) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) developed for the treatment and prevention of HIV-1 infection.
  22. GC62210 ONX-0914 TFA A selective inhibitor of the β5i (LMP7) subunit of the immunoproteasome
  23. GC61879 Nifeviroc Nifeviroc 是具有口服活性的 CCR5 拮抗剂。Nifeviroc 可用于 HIV-1 感染研究。
  24. GC61820 IMB-301 IMB-301 是一种 HIV-1 辅助蛋白 Vif 降解 hA3G 的拮抗剂。IMB-301 通过抑制 hA3G-Vif 相互作用，来抑制 Vif 降解 hA3G。IMB-301 具有抗 HIV-1 活性。
  25. GC61753 2-Hydroxycinnamic acid 2-Hydroxycinnamicacid是从肉桂的甲醇提取物中分离出的。2-Hydroxycinnamicacid对HIV/SARS-CoVS假病毒的感染具有抑制作用，IC50为0.3mM。
  26. GC61674 2-Hydroxyacetophenone 2-Hydroxyacetophenone是Carissaedulis的主要根挥发物。2-Hydroxyacetophenone对HIV/SARS-CoVS假病毒的感染具有抑制作用，IC50为1.8mM。
  27. GC61633 Peldesine dihydrochloride Peldesine(BCX34)dihydrochloride是一种有效的，竞争性，可逆和口服活性的嘌呤核苷磷酸化酶(PNP)抑制剂，对人，大鼠和小鼠红细胞(RBC)PNP的IC50分别为36nM，5nM和32nM。Peldesinedihydrochloride还是一种T细胞(T-cell)增殖抑制剂，IC50为800nM。Peldesinedihydrochloride可用于皮肤T细胞淋巴瘤，牛皮癣和HIV感染的研究。
  28. GC48488 3-Oxobetulin Acetate A derivative of betulin
  29. GC48446 Betulin 3,28-diacetate A triterpene with antiviral and hepatoprotective activities
  30. GC48359 DAPTA (acetate) A CCR5 receptor antagonist
  31. GC48143 Tenofovir-d6 An internal standard for the quantification of tenofovir
  32. GC48096 Sporogen-AO 1 A fungal metabolite with diverse biological activities
  33. GC47963 Plerixafor-d4 An internal standard for the quantification of plerixafor
  34. GC47810 O-11 A myristic acid analog with selective toxicity for trypanosomes
  35. GC47770 Nevirapine-d4 An internal standard for the quantification of nevirapine
  36. GC47741 Nalanthalide A fungal metabolite with potassium channel inhibitory and antiviral activities
  37. GC47573 Lopinavir-d8 An internal standard for the quantification of lopinavir
  38. GC47572 L-Lysine lactam (hydrochloride) A building block
  39. GC47455 Indinavir-d6 An internal standard for the quantification of indinavir
  40. GC47398 Genistein-d4 An internal standard for the quantification of genistein
  41. GC47173 Darunavir-d9 An internal standard for the quantification of darunavir
  42. GC46895 Aurintricarboxylic Acid (ammonium salt) A protein synthesis inhibitor with diverse biological activities
  43. GC46887 Atazanavir-d6 An internal standard for the quantification of atazanavir
  44. GC46805 Adefovir-d4 An internal standard for the quantification of adefovir
  45. GC46767 Abacavir-d4 An internal standard for the quantification of abacavir
  46. GC46721 6-Chloro-2-fluoropurine A heterocyclic building block
  47. GC46508 2',2'-Difluoro-2'-deoxyuridine An active metabolite of gemcitabine
  48. GC46415 12-Bromododecanoic Acid A halogenated form of lauric acid
  49. GC46245 (-)-G-Lactone A bicyclic γ-lactone
  50. GC61284 Soyasaponin II SoyasaponinII是具有抗病毒活性的皂苷。SoyasaponinII抑制HSV-1，HCMV，流感病毒和HIV-1的复制。SoyasaponinII对HSV-1复制显示出有效的抑制作用。SoyasaponinII作为YB-1磷酸化和NLRP3炎性小体引发的抑制剂，可保护小鼠免受LPS/GalN诱导的急性肝衰竭。
  51. GC61171 Pentosan Polysulfate Sodium (W/W 43%) 

    PentosanPolysulfateSodium是一种口服生物可利用的半合成药物，具有抗炎和促软骨生成的特性。PentosanPolysulfateSodium也是一种有效和选择性的抗HIV药物。PentosanPolysulfateSodium用于间质性膀胱炎的研究。

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