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HIV(人类免疫缺陷病毒)

HIV (human immunodeficiency virus) is a lentivirus that infect immune system. It cause immune system failure and lead to AIDS (acquired immnudeficiency syndrome).

Products for  HIV

  1. Cat.No. 产品名称 Information
  2. GC33842 3-Deazaadenosine hydrochloride An inhibitor of S-adenosylhomocysteine
  3. GC33536 Etravirine D4 (TMC-125 D4) Etravirine D4 (TMC-125 D4) (TMC-125 D4) 是氘标记的 Etravirine。
  4. GC32390 MIV-150 (PC 815) A non-nucleoside reverse transcriptase inhibitor
  5. GC32367 CCR5 antagonist 1

    CCR5antagonist1是一个CCR5拮抗剂,能够抑制HIV病毒的复制来自专利WO2004054974A2。

  6. GC32362 Fosamprenavir (Amprenavir phosphate) Fosamprenavir (Amprenavir phosphate) (Amprenavir phosphate;GW 433908) 是抗逆转录病毒蛋白酶抑制剂 Amprenavir 的磷酸酯前药,具有改善的溶解度。
  7. GC32358 Loviride (R 89439) Loviride (R 89439) (R 89439) 是一种非核苷类逆转录酶抑制剂 (NNRTI),抑制 HIV-1 逆转录酶的 IC50 为 0.3 μM。
  8. GC32342 HIV-1 Rev 34-50 (HIV-1 rev Protein (34-50)) HIV-1 Rev 34-50(HIV-1 rev 蛋白 (34-50))是一种 17-aa 肽,来源于 HIV-1 中 Rev 的 Rev 反应元件 (RRE) 结合域,具有抗 HIV- 1个活动。
  9. GC32336 Aplaviroc (AK 602) Aplaviroc (AK 602) (AK 602) 是一种 SDP 衍生物,是一种 CCR5 拮抗剂,对 HIV-1Ba-L、HIV-1JRFL 和 HIV-1MOKW 的 IC50 值为 0.1-0.4 nM。
  10. GC32335 Peptide T TFA PeptideT(TFA)是源自HIV-1gp120的V2区的八肽。PeptideT是CD4受体的配体,可阻止HIV与CD4受体结合。
  11. GC32327 PNU-103017 PNU-103017是一种HIV蛋白酶抑制剂。
  12. GC32309 Peptide T PeptideT是源自HIV-1gp120的V2区的八肽。PeptideT是CD4受体的配体,可阻止HIV与CD4受体结合。
  13. GC32306 Islatravir (MK-8591) A nucleoside reverse transcriptase inhibitor
  14. GC32210 Gomisin G 戈米辛G(GomisinG)是一抗HIV活性的天然化合物。
  15. GC32192 Sodium copper chlorophyllin 叶绿素铜钠对流感病毒和 HIV 具有抗病毒活性,IC50 为 50 至 100 μM 两者。
  16. GC32191 Celgosivir (MBI 3253) Celgosivir (MBI 3253) (MBI 3253; MDL 28574; MX3253) 是一种 α-葡萄糖苷酶 I 抑制剂;体外试验中抑制牛病毒性腹泻病毒 (BVDV),IC50 为 1.27 μM。
  17. GC32145 ABX464 ABX464 (SPL-464) is a novel anti-HIV molecule that inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs) from 5 different donors with IC50 ranging between 0.1 μM and 0.5 μM.
  18. GC32142 Ditiocarb sodium (Sodium diethyldithiocarbamate) Ditiocarb sodium (Sodium diethyldithiocarbamate) (Sodium diethyldithiocarbamate) 是铜胶结率的促进剂。
  19. GC32135 TAK-220 A CCR5 antagonist
  20. GC32124 Trovirdine (LY300046) Trovirdine (LY300046) 在使用异聚引物/模板(寡-DNA/核糖体 RNA)和 dGTP 作为底物时抑制 HIV-1 RT,IC50 为 7 nM。
  21. GC32110 Vesnarinone (OPC-8212) A PDE3 inhibitor and ERG1 channel blocker
  22. GC32074 Celgosivir hydrochloride (MBI 3253 (hydrochloride)) Celgosivir hydrochloride (MBI 3253 (hydrochloride)) (MBI 3253 hydrochloride; MDL 28574 hydrochloride; MX3253 hydrochloride) 是一种 α-葡萄糖苷酶 I 抑制剂;体外试验中抑制牛病毒性腹泻病毒 (BVDV),IC50 为 1.27 μM。
  23. GC32060 Bictegravir (GS-9883) An HIV-1 integrase inhibitor
  24. GC31881 MS417 (GTPL7512)

    MS417 (GTPL7512) 是一种选择性 BET 特异性 BRD4 抑制剂,与 BRD4-BD1 和 BRD4-BD2 结合,IC50 分别为 30、46 nM 和 Kds 分别为 36.1、25.4 nM,对 CBP BRD 的选择性较弱 (IC50, 32.7 &#956 ;M)。

  25. GC31715 Letrazuril Letrazuril是双胍类的对映体类似物,是一种苯乙腈可用于预防和治疗家禽中的球虫感染。
  26. GC31685 Pentosan Polysulfate Pentosan Polysulfate Sodium (PPS, Elmiron) is an orally bioavailable, semi-synthetic medication with anti-inflammatory and pro-chondrogenic properties. Pentosan Polysulfate Sodium also exhibits anti-HIV-1 activity.
  27. GC31140 Oxindole (Indolin-2-one)

    An aromatic heterocycle and starting material

  28. GC30862 L-Cycloserine ((S)-4-Amino-3-isoxazolidone) An inhibitor of sphingolipid synthesis and aminotransferases
  29. GC30119 9-Aminoacridine (Aminacrine) 9-Aminoacridine (Aminacrine) is a highly fluorescent dye used clinically as a topical antiseptic and experimentally as a mutagen, an intracellular pH indicator and a negative mode small molecule MALDI matrix.
  30. GC19409 ABBV-744 A BD2 bromodomain inhibitor
  31. GC19126 Doravirine A non-nucleoside reverse transcriptase inhibitor
  32. GC19101 Cenicriviroc An antagonist of CCR5 and CCR2
  33. GC18964 Palitantin A fungal metabolite
  34. GC18853 4-isocyanato TEMPO A spin label for RNA
  35. GC18778 16,16-dimethyl Prostaglandin A1 An inhibitor of HSV and HIV-1 viral replication
  36. GC18749 (+)-Rugulosin A mycotoxin
  37. GC18745 Integracin A An HIV-1 integrase inhibitor
  38. GC18659 Ribavirin 5'-monophosphate (lithium salt) A potent, broad-spectrum antiviral agent
  39. GC18601 Stachybotrylactam A mycotoxin
  40. GC18545 Ilimaquinone A natural sesquiterpene quinone
  41. GC18516 (+)-Aeroplysinin-1 A sea sponge metabolite with diverse biological activities
  42. GC18484 GSK2578999A
  43. GC18456 Digallic Acid A natural polyphenolic
  44. GC18382 RN-18 An HIV-1 Vif inhibitor
  45. GC18345 Leptomycin A An inhibitor of nuclear transport
  46. GP10160 Oritavancin(LY-333328) Oritavancin(LY-333328) (LY 333328) 是一种具有口服活性的糖肽抗生素,对革兰氏阳性菌具有活性。
  47. GC10520 Dextran sulfate sodium salt (M.W 200000) A sulfated polysaccharide
  48. GC17632 Maslinic Acid A biologically active triterpene
  49. GC17015 DRB A CTD kinase inhibitor
  50. GC18042 Isoprinosine An immunomodulatory antiviral complex
  51. GC10331 Ebselen A peroxynitrite scavenger

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