Autophagy(自噬)

Autophagy is a catabolic process which degrades and recycles long-lived proteins and cytoplasmic organelles through lysosome. It plays an important role in growth regulation and maintenance of homeostasis.

Products for Autophagy

Cat.No. 产品名称 Information
GC15184 Taurine
牛磺酸; 2-Aminoethanesulfonic acid
A sulfur-containing amino acid
GC13918 STF-62247
N-(3-甲基苯基)-4-(4-吡啶)-2-噻唑胺
Inducer of autophagy in renal cell carcinoma cells
GC12516 Spironolactone
螺内酯; SC9420
An Analytical Reference Standard
GC11033 Rupatadine Fumarate
富马酸卢帕他定; UR-12592 Fumarate
A histamine H₁ and PAF receptor antagonist
GC14263 Proflavine Hemisulfate
硫酸原黄素,Proflavin hemisulfate; 3,6-Diaminoacridine hemisulfate
Proflavine hemisulfate，一种吖啶染料，是一种已知的 DNA 嵌入剂。
GC10458 Penfluridol
五氟利多; R-16341
A typical antipsychotic
GC10678 Nicardipine HCl
盐酸尼卡地平; YC-93
An L-type calcium channel blocker
GC13252 Meclizine 2HCl
盐酸美克洛嗪; Meclozine dihydrochloride
A histamine H₁ receptor antagonist
GC15929 Levosimendan
左西孟旦; Simsndan; OR-1259
A calcium sensitizer
GC14764 Lamotrigine
拉莫三嗪; LTG; BW430C
An anticonvulsant
GC15826 Isosorbide
异山梨酯; D-Isosorbide; Dianhydro-D-glucitol
A dianhydrohexitol
GC10074 H 89 2HCl
H-89二盐酸盐
H-89 2HCl 是一种有效的选择性 camp 依赖性蛋白激酶 A 抑制剂，IC50 值为 48 nM，对 PKG、PKC、酪蛋白激酶和其他激酶表现出较弱的抑制作用。
GC17173 Felodipine
非洛地平
An L-type calcium channel inhibitor
GC14968 Esmolol HCl
盐酸艾司洛尔
A β₁-AR antagonist
GC10326 Erythromycin Ethylsuccinate
琥乙红霉素; Erythromycin ethyl succinate; EES
Erythromycin Ethylsuccinate 是一种可用于治疗多种细菌感染的抗生素，其抗菌谱与青霉素相似或略宽。
GC12846 Elaiophylin
洋橄榄叶素,Azalomycin B; Gopalamicin; Efomycin E
A macrodiolide antibiotic
GC13502 Cysteamine HCl
半胱胺盐酸盐; 2-Aminoethanethiol hydrochloride; 2-Mercaptoethylamine hydrochloride
A radioprotective aminothiol
GC16332 Colistin Sulfate
硫酸粘杆菌素; Polymyxin E sulfate
An antibiotic
GC15810 Clinofibrate
克利贝特,S-8527
A hypolipidemic agent
GC14892 Clemastine Fumarate
富马酸氯马斯汀; HS-592 fumarate; Meclastine fumarate
A histamine H₁ receptor antagonist
GC14421 CFTRinh-172
CFTR(inh)172, Cystic Fibrosis Transmembrane Conductance Regulator Inhibitor 172
A potent CFTR channel blocker
GC17341 Carprofen
卡洛芬
An NSAID used in animals
GC12733 C646 C646是一种有效的选择性p300/CBP组蛋白乙酰转移酶抑制剂(Ki 400 nM),已被证明具有多效性,包括神经保护、抗癌和抗上皮间质转化(anti-EMT)作用。
GC17683 Brefeldin A
布雷非德菌素 A; BFA; Cyanein; Decumbin
Brefeldin A（BFA）是一种真菌大环内酯，能够有效、可逆地抑制内质网和高尔基体之间的蛋白质运输和囊泡形成。
GC11304 Azithromycin Dihydrate
阿奇霉素二水合物; CP-62993 dihydrate
A macrolide antibiotic
GC14314 Aloperine
苦豆碱
An alkaloid with diverse biological activities
GC13854 AG-490 (Tyrphostin B42)
酪氨酸磷酸化抑制剂AG490
AG-490 (Tyrphostin B42)是EGFR抑制剂,IC50为0.1 µM, AG-490对JAK2也有抑制作用。
GC13843 Pyrazinamide
吡嗪酰胺; Pyrazinecarboxamide; Pyrazinoic acid amide
An antimycobacterial compound
GC17340 Carbamazepine
卡马西平; CBZ; NSC 169864
卡马西平是一种钠通道阻滞剂，是一种抗惊厥药。
GC15668 Meprednisone
泼尼松
A corticosteroid
GC15493 Enalaprilat Dihydrate
2,4-二氯苯基-2-(-1H-咪唑)乙醇
The active metabolite of an ACE inhibitor
GC14106 Adenosine
腺苷; Adenine riboside; D-Adenosine
A purine nucleoside
GC12645 Imiquimod maleate
马来酸咪喹莫特; R 837 maleate

A TLR7 agonist
GC10712 Imiquimod hydrochloride
盐酸咪喹莫特; R 837 hydrochloride

A TLR7 agonist
GC12013 Sodium salicylate
水杨酸钠; Salicylic acid sodium salt; 2-Hydroxybenzoic acid sodium salt
水杨酸钠（水杨酸钠盐）抑制环加氧酶 2（COX-2）活性，与转录因子（NF-κB）激活无关。
GC16508 Salicylic acid
水杨酸; 2-Hydroxybenzoic acid
An Analytical Reference Standard
GC13870 Pravastatin
普伐他汀; CS-514
A potent HMG-CoA reductase inhibitor
GC12920 Pregnenolone
孕烯醇酮; 3β-Hydroxy-5-pregnen-20-one
A natural steroid hormone
GC11332 Pitavastatin
匹伐他汀; NK-104
Pitavastatin (NK-104) 是一种有效的羟甲基戊二酰辅酶A (HMG-CoA) 还原酶抑制剂。
GC13206 Nicotinic Acid
烟酸; Nicotinic acid; Vitamin B3
烟酸（维生素 B3）是一种具有口服活性的水溶性维生素 B3，是人体必需的营养素。
GC16441 Tigecycline mesylate
甲磺酸替加环素; GAR-936 mesylate
A glycylcycline antibiotic
GC16410 Tigecycline hydrochloride
盐酸替加环素; GAR-936 hydrochloride
A glycylcycline antibiotic
GC12830 Stavudine (d4T)
司他夫定; d4T
An inhibitor of HIV reverse transcriptase
GC17113 Acitretin sodium
阿维A钠; Ro 10-1670 sodium
A retinoid
GC14379 Adapalene sodium salt
阿达帕林钠; CD 271 sodium salt
An RARβ and RARγ agonist
GC15578 Dienogest
地诺孕素; STS 557
A synthetic progestin and PR agonist
GC16716 Sulindac
舒林酸; MK-231
A non-selective COX inhibitor
GC14769 Carvedilol
卡维地洛; BM 14190
A β-adrenergic receptor antagonist
GC17985 Chenodeoxycholic Acid
鹅去氧胆酸
A primary bile acid
GC12234 Dronedarone HCl
盐酸决奈达隆
An antiarrhythmic agent