ERK(细胞外信号调节激酶)
ERK (extracellular-signal-regulated kinase), also known as MAPK, is involved in the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells.
- Cat.No. 产品名称 Information
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GC67905
ERK1/2 inhibitor 7
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GC65510
ERK1/2 inhibitor 1
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GC64496
EF24
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GC64035
Hirsutenone
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GC63903
(E)-Osmundacetone
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GC63459
ERK-IN-3 benzenesulfonate
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GC62448
Rineterkib hydrochloride
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GC62229
ERK-IN-3
ASN007(ERAS 007, ERK-IN-3) is a potent and orally active inhibitor of ERK. ERK-IN-3 inhibits ERK1/2 with 2 nM IC50 values. ERK-IN-3 can be used for the research of cancers driven by RAS mutations.
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GC61865
Cearoin
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GC61466
DMU-212
DMU-212 is a methylated derivative of Resveratrol, with antimitotic, anti-proliferative, antioxidant and apoptosis promoting activities, which can induce mitotic arrest via induction of apoptosis and activation of extracellular-signal-regulated kinase1/2 (ERK1/2) protein.
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GC39485
CK2/ERK8-IN-1
A dual inhibitor of CK2 and ERK8
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GC39325
2,5-Dihydroxyacetophenone
2',5'-Dihydroxyacetophenone (DHAP, 2-Acetylhydroquinone, Quinacetophenone) is a mixture of dihydroxyacetophenone isomers is used in food flavouring. 2',5'-Dihydroxyacetophenone significantly inhibits NO production via the suppression of iNOS expression. 2',5'-Dihydroxyacetophenone significantly decreases levels of the pro-inflammatory cytokines TNF-α and IL-6 by blocking the ERK1/2 and NF-κB signaling pathways.
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GC39074
Tenuifoliside A
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GC38804
JWG-071
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GC38679
Urolithin B
A metabolite of ellagic acid
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GA20623
Ac-muramyl-Ala-D-Glu-NH₂
Ac-muramyl-Ala-D-Glu-NH₂ (MDP) 是一种合成的免疫反应肽,由连接到 L-Ala-D-isoGln 短氨基酸链上的 N-乙酰胞壁酸组成。
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GC37071
Ravoxertinib hydrochloride
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GC36596
Methylnissolin
A flavonoid with antiproliferative activity
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GC36002
ERK5-IN-2
ERK5-IN-2 is an orally active, sub-micromolar, selective ERK5 inhibitor with IC50 of 0.82 μM and 3 μM for ERK5 and ERK5 MEF2D, respectively.
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GC35674
Chicanine
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GC35412
Asperulosidic Acid
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GC44085
L-Sulforaphene
A natural isothiocyanate
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GC43885
Hypothemycin
A resorcylic acid lactone polyketide with diverse biological activities
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GC43611
Enniatin B1
An antibiotic ionophore
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GC43610
Enniatin A1
An ionophore antibiotic
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GC41573
Theaflavin 3,3'-digallate
A polyphenol with diverse biological activities
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GC40352
Cafestol
A natural diterpene which increases serum cholesterol
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GC34831
Tauroursodeoxycholate dihydrate
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GC34650
Longdaysin
Longdaysin is a Casein Kinase inhibitor with IC50 values of 8.8 μM, 5.6 μM, 52 μM and 29 μM for CKIδ, CKIα, ERK2 and CDK7.
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GC34342
BAY885
An ERK5 inhibitor
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GC34181
Tauroursodeoxycholate (TUDCA)
A taurine-conjugated form of ursodeoxycholic acid
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GC34057
TBHQ (tert-Butylhydroquinone)
Tert-butylhydroquinone (TBHQ) is an antioxidant compound which is used to prevent lipid peroxidation and shows multiple cytoprotective actions. It is an activator of Nrf2.
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GC33857
Omtriptolide
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GC33831
Lidocaine hydrochloride (Lignocaine hydrochloride)
An Analytical Reference Standard
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GC33206
ERK-IN-1
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GC33051
KO-947
An ERK inhibitor
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GC32900
CC-90003
CC-90003 is an irreversible inhibitor of ERK1/2 with IC50s in the 10-20 nM range and shows good kinase selectivity in a 258-kinase biochemical assay.
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GC32796
ERK5-IN-1
An ERK5 inhibitor
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GC32789
Mogrol
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GC32254
Deltonin
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GC31735
Magnolin
A lignan with anti-inflammatory and anticancer activities
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GC31667
AX-15836
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GC30770
LM22B-10
An activator of TrkB and TrkC
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GC30162
trans-Zeatin
A cytokinin plant growth regulator
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GC18156
MK8353
MK8353 (SCH900353) 是一种有效的、选择性的、可口服的 ERK1/2 抑制剂,IC50 分别为 23.0 nM 和 8.8 nM; MK8353 具有抗肿瘤活性。
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GC19235
LY3214996
An ERK1/2 inhibitor
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GC19048
AZD-0364
An inhibitor of ERK1/2
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GC17265
AG-126
Tyrosine kinase inhibitor that blocks ERK1/2 phosphorylation
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GC11422
Ulixertinib (hydrochloride)
An ERK1/2 inhibitor
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GC17693
Enniatin B
A natural inhibitor of Pdr5p in yeast