Home >> Signaling Pathways >> MAPK Signaling >> ERK


ERK (extracellular-signal-regulated kinase), also known as MAPK, is involved in the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells.

  1. Cat.No. 产品名称 Information
  2. GC67905 ERK1/2 inhibitor 7
  3. GC65510 ERK1/2 inhibitor 1
  4. GC64496 EF24
  5. GC64035 Hirsutenone
  6. GC63903 (E)-Osmundacetone
  7. GC63459 ERK-IN-3 benzenesulfonate
  8. GC62448 Rineterkib hydrochloride
  9. GC62229 ERK-IN-3 ASN007(ERAS 007, ERK-IN-3) is a potent and orally active inhibitor of ERK. ERK-IN-3 inhibits ERK1/2 with 2 nM IC50 values. ERK-IN-3 can be used for the research of cancers driven by RAS mutations.
  10. GC61865 Cearoin
  11. GC61466 DMU-212 DMU-212 is a methylated derivative of Resveratrol, with antimitotic, anti-proliferative, antioxidant and apoptosis promoting activities, which can induce mitotic arrest via induction of apoptosis and activation of extracellular-signal-regulated kinase1/2 (ERK1/2) protein.
  12. GC39485 CK2/ERK8-IN-1 A dual inhibitor of CK2 and ERK8
  13. GC39325 2,5-Dihydroxyacetophenone 2',5'-Dihydroxyacetophenone (DHAP, 2-Acetylhydroquinone, Quinacetophenone) is a mixture of dihydroxyacetophenone isomers is used in food flavouring. 2',5'-Dihydroxyacetophenone significantly inhibits NO production via the suppression of iNOS expression. 2',5'-Dihydroxyacetophenone significantly decreases levels of the pro-inflammatory cytokines TNF-α and IL-6 by blocking the ERK1/2 and NF-κB signaling pathways.
  14. GC39074 Tenuifoliside A
  15. GC38804 JWG-071
  16. GC38679 Urolithin B A metabolite of ellagic acid
  17. GA20623 Ac-muramyl-Ala-D-Glu-NH₂ Ac-muramyl-Ala-D-Glu-NH₂ (MDP) 是一种合成的免疫反应肽,由连接到 L-Ala-D-isoGln 短氨基酸链上的 N-乙酰胞壁酸组成。
  18. GC37071 Ravoxertinib hydrochloride
  19. GC36596 Methylnissolin A flavonoid with antiproliferative activity
  20. GC36002 ERK5-IN-2 ERK5-IN-2 is an orally active, sub-micromolar, selective ERK5 inhibitor with IC50 of 0.82 μM and 3 μM for ERK5 and ERK5 MEF2D, respectively.
  21. GC35674 Chicanine
  22. GC35412 Asperulosidic Acid
  23. GC44085 L-Sulforaphene A natural isothiocyanate
  24. GC43885 Hypothemycin A resorcylic acid lactone polyketide with diverse biological activities
  25. GC43611 Enniatin B1 An antibiotic ionophore
  26. GC43610 Enniatin A1 An ionophore antibiotic
  27. GC41573 Theaflavin 3,3'-digallate A polyphenol with diverse biological activities
  28. GC40352 Cafestol A natural diterpene which increases serum cholesterol
  29. GC34831 Tauroursodeoxycholate dihydrate
  30. GC34650 Longdaysin

    Longdaysin is a Casein Kinase inhibitor with IC50 values of 8.8 μM, 5.6 μM, 52 μM and 29 μM for CKIδ, CKIα, ERK2 and CDK7.

  31. GC34342 BAY885 An ERK5 inhibitor
  32. GC34181 Tauroursodeoxycholate (TUDCA) A taurine-conjugated form of ursodeoxycholic acid
  33. GC34057 TBHQ (tert-Butylhydroquinone) Tert-butylhydroquinone (TBHQ) is an antioxidant compound which is used to prevent lipid peroxidation and shows multiple cytoprotective actions. It is an activator of Nrf2.
  34. GC33857 Omtriptolide
  35. GC33831 Lidocaine hydrochloride (Lignocaine hydrochloride) An Analytical Reference Standard
  36. GC33206 ERK-IN-1
  37. GC33051 KO-947 An ERK inhibitor
  38. GC32900 CC-90003 CC-90003 is an irreversible inhibitor of ERK1/2 with IC50s in the 10-20 nM range and shows good kinase selectivity in a 258-kinase biochemical assay.
  39. GC32796 ERK5-IN-1 An ERK5 inhibitor
  40. GC32789 Mogrol
  41. GC32254 Deltonin
  42. GC31735 Magnolin A lignan with anti-inflammatory and anticancer activities
  43. GC31667 AX-15836
  44. GC30770 LM22B-10 An activator of TrkB and TrkC
  45. GC30162 trans-Zeatin A cytokinin plant growth regulator
  46. GC18156 MK8353 MK8353 (SCH900353) 是一种有效的、选择性的、可口服的 ERK1/2 抑制剂,IC50 分别为 23.0 nM 和 8.8 nM; MK8353 具有抗肿瘤活性。
  47. GC19235 LY3214996 An ERK1/2 inhibitor
  48. GC19048 AZD-0364 An inhibitor of ERK1/2
  49. GC17265 AG-126 Tyrosine kinase inhibitor that blocks ERK1/2 phosphorylation
  50. GC11422 Ulixertinib (hydrochloride) An ERK1/2 inhibitor
  51. GC17693 Enniatin B A natural inhibitor of Pdr5p in yeast

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