ERK(细胞外信号调节激酶)

ERK (extracellular-signal-regulated kinase), also known as MAPK, is involved in the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells.

Products for ERK

Cat.No. 产品名称 Information
GC17265 AG-126 Tyrosine kinase inhibitor that blocks ERK1/2 phosphorylation
GC11422 Ulixertinib (hydrochloride) An ERK1/2 inhibitor
GC17693 Enniatin B A natural inhibitor of Pdr5p in yeast
GC16214 DEL-22379 An inhibitor of ERK dimerization
GC17425 Sodium Tauroursodeoxycholate (TUDC) Tauroursodeoxycholate (Tauroursodeoxycholic acid; TUDCA) sodium 是一种内质网 (ER) 应激抑制剂。 Tauroursodeoxycholate 显着降低凋亡分子的表达，例如 caspase-3 和 caspase-12。 Tauroursodeoxycholate 也抑制 ERK。
GC12006 GDC-0994 A selective ERK1/2 inhibitor
GC17963 CHPG Sodium salt CHPG 钠盐是一种选择性 mGluR5 激动剂，可通过 BV2 小胶质细胞中的 TSG-6/NF-κB 通路减弱 SO2 诱导的氧化应激和炎症。
GC12532 CHPG A potent and selective mGluR5 agonist
GC17407 Pluripotin A synthetic compound that promotes self-renewal of murine embryonic stem cells
GC16007 Methylthiouracil 甲基硫氧嘧啶是一种抗甲状腺药物。
GC17031 VRT752271 VRT752271 (BVD-523; VRT752271) 是一种有效的、具有口服活性、高度选择性、ATP 竞争性和可逆的 ERK1/2 激酶共价抑制剂，对 ERK2 的 IC50 <0.3 nM。 VRT752271 (BVD-523; VRT752271) 抑制 A375 黑色素瘤细胞系中的磷酸化 ERK2 (pERK) 和下游激酶 RSK (pRSK)。
GC10647 FR 180204 A potent, cell-permeable inhibitor of ERK1/2
GC15693 BIX 02188 A potent MEK5 inhibitor
GC12220 BIX 02189 An inhibitor of MEK5 and ERK5
GC17608 Lidocaine An Analytical Reference Standard
GC10282 Piperlongumine An alkaloid with anticancer and antioxidant activities
GC11076 XMD8-92 A selective ERK5 inhibitor
GC12691 XMD17-109 A selective ERK5 inhibitor
GC13115 VX-11e A selective ERK inhibitor
GC16001 SCH772984
A selective inhibitor of ERK1/2
GN10267 Loureirin B A flavonoid with diverse biological activities
GN10752 Pachymic acid A triterpenoid with diverse biological activities
GN10481 Corynoxeine An alkaloid with diverse biological activities
GN10494 Astragaloside IV A bioactive saponin from Astragalus
GN10664 Honokiol A natural lignan with diverse physiological effects