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Home >> Signaling Pathways >> Neuroscience >> GABA Receptor

GABA Receptor(γ-氨基丁酸受体)

GABA receptors are a class of receptors that respond to the GABA (neurotransmitter gamma-aminobutyric acid), the chief inhibitory neurotransmitter in the vertebrate central nervous system.

Products for  GABA Receptor

  1. Cat.No. 产品名称 Information
  2. GC36058 Flumazenil acid Flumazenil acid 是 Flumazenil 的一种代谢产物。Flumazenil 是一种 GABAA 受体拮抗剂。
  3. GC36012 Etifoxine A positive allosteric modulator of GABAA receptors
  4. GC35975 Emamectin Benzoate Emamectin Benzoate (EMB, MK-244) activates gamma-amino butyric acid (GABA) transporter. Emamectin Benzoate induces of reactive oxygen species (ROS)-mediated DNA damage and apoptosis.
  5. GC35669 CGP 36742 A GABAB receptor antagonist
  6. GC34986 (R)-Baclofen hydrochloride A GABAB receptor agonist
  7. GC34954 (+)-Borneol A bicyclic monoterpene with diverse biological activities
  8. GC44841 Riluzole (hydrochloride) An inhibitor of glutamatergic transmission
  9. GC44040 LAU159 A positive allosteric modulator of α6β3γ2 subunit-containing GABAA receptors
  10. GC43261 Cholesteryl Myristate A cholesterol ester
  11. GC41613 Valnoctamide An anxiolytic that suppresses seizures
  12. GC34494 Bifenazate An acaricide
  13. GC34362 SSD114 hydrochloride SSD114hydrochloride是一种新型GABAB受体正变构调节剂。
  14. GC34064 Aminooxyacetic acid hemihydrochloride (Carboxymethoxylamine Hemihydrochloride) A GABA-T inhibitor
  15. GC33754 FG8119 (NNC13-8119) FG8119 (NNC13-8119) 是一种从美国专利 4745112 A 中提取的新型苯二氮卓类激动剂。
  16. GC33751 CGP11952 CGP11952是一种三唑基Benzaphenon。CGP11952是一种苯二氮卓类(benzodiazepine)衍生物。
  17. GC33703 3,4,5-Trimethoxycinnamic acid 3,4,5-Trimethoxycinnamic acid (TMCA) is one of the constituents of Polygalae Radix and may exert anti-seizure activity by acting at the GABAA/BZ receptor complex.
  18. GC33504 4-Acetamidobutanoic acid (N-acetyl GABA) A GABA derivative
  19. GC31990 Bamaluzole Bamaluzole是一个GABA受体激动剂，来自专利WO2012064642A1。
  20. GC31282 p-Hydroxybenzaldehyde p-Hydroxybenzaldehyde (4-Hydroxybenzaldehyde, 4-Formylphenol, p-Formylphenol), which can be found in the orchids Gastrodia elata, Galeola faberi and vanilla, is a hydroxybenzaldehyde that reacts with NAD+ and H2O to produce 4-hydroxybenzoate, NADH, and 2 protons. p-Hydroxybenzaldehyde at 101.7 μM can significantly reduce the GABA-induced chloride current of GABAA receptors(α1β2γ2S subtype) expressed.
  21. GC31257 Rilmazafone hydrochloride (450191S) Rilmazafone hydrochloride (450191S) (450191S) 是苯二氮卓 (omega) 配体。
  22. GC31224 Carburazepam (RGH 3331) Carburazepam (RGH 3331) 是一种衍生自苯二氮卓类药物的药物。
  23. GC31196 SX-3228 SX-3228是一种选择性苯二氮卓类(benzodiazepine1，BZ1)受体激动剂，IC50为17nM。
  24. GC31142 Uldazepam (U31920) Uldazepam (U31920) 是一种苯二氮卓类衍生物，具有治疗焦虑症的潜力。
  25. GC31121 S-8510 phosphate (SB-737552 phosphate) S-8510 (phosphate) 是一种反向苯二氮卓 (BDZ) 受体激动剂，对 -GABA 和 +GABA 的 Kis 分别为 34.6 nM、36.2 nM。
  26. GC31120 Cirsimaritin A flavone with diverse biological activities
  27. GC31112 Sarmazenil (Ro 15-3505) Sarmazenil (Ro 15-3505) 是一种苯二氮卓受体拮抗剂。
  28. GC31052 CP-409092 CP-409092是GABA(A)的部分激动剂，主要用于抗焦虑研究。
  29. GC31049 RWJ-51204 RWJ-51204是GABA(A)receptor的部分激动剂，Ki值为0.2-2nM。
  30. GC31023 Ethyl dirazepate Ethyldirazepate是一种苯并二氮杂(benzodiazepine)衍生物。具有抗焦虑和催眠特性。
  31. GC31018 NEO 376 (SPI-376) NEO 376 (SPI-376) 是 5-HT1 受体、GABA 受体和多巴胺受体的选择性调节剂，具有抗精神病活性。
  32. GC31013 U-101017 (PNU 101017) U-101017 (PNU 101017) 是苯二氮卓受体和 GABAA 受体的部分激动剂，具有抗焦虑作用。
  33. GC31010 AZD-6280 AZD-6280 is a selective GABAA (α2/3) receptor modulator, used for treatment of generalized anxiety disorder.
  34. GC30983 alpha-Asarone (α-Asarone) An inhibitor of HMG-CoA reductase and CYP450 isoforms
  35. GC30943 6,2'-Dihydroxyflavone 6,2'-Dihydroxyflavone是一个新型的GABAA受体拮抗剂。
  36. GC30933 (+)-Kavain A kavalactone with diverse biological activities
  37. GC30930 DAA-1106 A TSPO agonist
  38. GC30898 6-Methylflavone 6-methylflavone是α1β2γ2L和α1β2GABAA受体的激活剂。
  39. GC30889 (-)-Securinine An alkaloid
  40. GC30865 TPA 023 TPA023是GABAAα2/α3的选择性的激动剂，Ki值为0.19-0.41nM。
  41. GC30862 L-Cycloserine ((S)-4-Amino-3-isoxazolidone) An inhibitor of sphingolipid synthesis and aminotransferases
  42. GC30844 Afloqualone An Analytical Reference Standard
  43. GC30827 Pipequaline (PK-8165) A partial agonist of central benzodiazepine receptors
  44. GC30521 Broflanilide Broflanilide是一种杀虫剂，可以分解成desmethyl-broflanilide，为特异性的昆虫耐狄氏剂的GABAreceptor拮抗剂，抑制斜纹夜蛾RDLGABAR，IC50值为1.3nM。
  45. GC30433 Ru-32514 Ru-32514是一种苯二氮受体(benzodiazepinereceptor)激动剂。
  46. GC30088 Fluxametamide Fluxametamide是一种广谱的杀虫剂，为GABA-和谷氨酸门控氯离子通道(chloridechannel)拮抗剂，对M.domestica中GABACl和GluCl的IC50值分别为1.95?nM和225?nM。
  47. GC19318 SAGE-217 A positive allosteric modulator of GABAA receptors
  48. GC19271 ONO-8590580 A negative allosteric modulator of α5 subunit-containing GABAA receptors
  49. GC19057 Basmisanil A negative allosteric modulator of α5 subunit-containing GABAA receptors
  50. GC18299 Lorediplon A ligand for α1 subunit-containing GABAA receptors
  51. GC11054 Epiallopregnanolone A neurosteroid

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