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Racecadotril-d5 Sale

(Synonyms: 消旋卡多曲杂质,Acetorphan-d5) 目录号 : GC49108

An internal standard for the quantification of racecadotril

Racecadotril-d5 Chemical Structure

Cas No.:1246815-11-1

规格 价格 库存 购买数量
1 mg
¥668.00
现货
5 mg
¥2,502.00
现货
10 mg
¥4,351.00
现货
25 mg
¥10,022.00
现货

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Sample solution is provided at 25 µL, 10mM.

产品文档

Quality Control & SDS

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产品描述

Racecadotril-d5 is intended for use as an internal standard for the quantification of racecadotril by GC- or LC-MS. Racecadotril is a prodrug form of the neprilysin (NEP) inhibitor thiorphan .1,2 In vivo, racecadotril reduces or prevents castor oil-induced diarrhea without delaying intestinal transit in rats when administered at doses of 80 or 100 mg/kg, respectively.1 It also decreases the duration of diarrhea and increases body weight gain in a neonatal gnotobiotic pig model of human rotavirus-induced diarrhea.2 Formulations containing racecadotril have been used in the treatment of acute diarrhea.

1.Griggs, D.W., Prinsen, M.J., Oliva, J., et al.Pharmacologic comparison of clinical neutral endopeptidase inhibitors in a rat model of acute secretory diarrheaJ. Pharmacol. Exp. Ther.357(2)423-431(2016) 2.Bui, T., Li, G., Kim, I., et al.Effects of racecadotril on weight loss and diarrhea due to human rotavirus in neonatal gnotobiotic pigs (Sus scrofa domesticus)Comp. Med.67(2)157-164(2017)

Chemical Properties

Cas No. 1246815-11-1 SDF
别名 消旋卡多曲杂质,Acetorphan-d5
Canonical SMILES [2H]C1=C([2H])C([2H])=C([2H])C([2H])=C1COC(CNC(C(CSC(C)=O)CC2=CC=CC=C2)=O)=O
分子式 C21H18D5NO4S 分子量 390.5
溶解度 DMSO: slightly soluble,Methanol: slightly soluble 储存条件 -20°C
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储备液的保存方式和期限:-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。
为了提高溶解度,请将管子加热至37℃,然后在超声波浴中震荡一段时间。
Shipping Condition 评估样品解决方案:配备蓝冰进行发货。所有其他可用尺寸:配备RT,或根据请求配备蓝冰。

溶解性数据

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1 mg 5 mg 10 mg
1 mM 2.5608 mL 12.8041 mL 25.6082 mL
5 mM 0.5122 mL 2.5608 mL 5.1216 mL
10 mM 0.2561 mL 1.2804 mL 2.5608 mL
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