Cat.No. 产品名称 Information

GC17184 Ambrisentan

安倍生坦; BSF 208075; LU 208075

ETA-receptor antagonist

GC11490 TCB-2 5-HT2A receptor agonist

GC12655 LPA2 antagonist 1

LPA2-IN-1

selective inhibitor of LPA2 activity

GN10020 Piperine

胡椒碱; Bioperine; 1-Piperoylpiperidine

MAPK inhibitor

GC15944 (-)-U-50488 hydrochloride

(-)-Trans-(1S,2S)-U-50488 hydrochloride

κ-opioid receptor agonist, selective

GC50531 QWF MRGPRX2 antagonist; also NK1 receptor antagonist

GC14815 GMX1778 (CHS828)

N-[6-(4-氯苯氧基)己基]-N'-氰基-N''-4-吡啶基胍,GMX1778

NAMPT inhibitor

GC16218 Astressin corticotropin-releasing factor (CRF) receptor antagonist

GC30778 Mavoglurant (AFQ056)

(3AR,4S,7AR)-八氢-4-羟基-4-[2-(3-甲基苯基)乙炔基]-1H-吲哚-1-羧酸甲酯,AFQ056

Mavoglurant是一种结构新颖的非竞争性mGlu5受体拮抗剂，IC50为30nM。

GC36367 JH-RE-06 JH-RE-06 is a potent REV1-REV7 interface inhibitor with an IC50 of 0.78 μM and Kd value of 0.42 μM, disrupting REV1-POL ζ-mediated mutagenic translesion synthesis (TLS).

GK10025 RIPA Lysis Buffer (Weak) 一种常用的细胞组织快速裂解液，在非变性条件下裂解细胞或组织样品，从而制备蛋白样品

GC26593 Apyrase

腺苷三磷酸双磷酸酶

Apyrase是一种核苷三磷酸二磷酸水解酶（NTPDase），可以催化水解NTPs和NDPs的末端磷酸基团。

GC30267 Pinacidil monohydrate

吡那地尔一水合物; P-1134 monohydrate

Pinacidilmonohydrate，一种抗高血压药，是一种钾通道激活剂。

GC39167 VBIT-4 VBIT-4是电压依赖性阴离子通道1（VDAC1）寡聚化的抑制剂，对纯化VDAC1的K_d值为3μM。

GB57336 Bis-(sodium sulfopropyl)-disulfide

双-（磺丙基钠)-二硫化物 Gamma,Gamma'-Sulfopropyldisulfide, Disodium Salt SPS 电子级

GC68893 Complete Freund's adjuvant (CFA)

Complete Freund's adjuvant (CFA)是一种参与抗原乳化的免疫佐剂，用于增强动物对抗原的免疫反应，因发现者Jules T. Freund而获名。

GC49476 IPG-4 AM

APG-4 Acetoxymethyl ester, APG-4 AM Asante Potassium Greeen-4 Acetoxymethyl ester, Asante Potassium Green-4 AM, Ion Potassium Green-4 Acetoxymethyl ester, IPG-4 Acetoxymethyl ester

A cell-permeable fluorescent potassium indicator

GC15426 SNAP 5089 α1A-adrenoceptor antagonist

GB59099 Lithium 3,5-diiodosalicylate

3,5-二碘水杨酸锂

GC69395 LONP1-IN-2 LONP1-IN-2 (compound 9d) 是一种有效的选择性 LONP1 抑制剂，对 LONP1 和 20S 蛋白酶体的 IC50 值分别为 0.187 μM 和 >10 μM。LONP1-IN-2可用于癌症研究。

GC37741 Tartaric acid disodium dihydrate

酒石酸钠,Sodium tartrate dibasic dihydrate; Sodium tartrate dihydrate

酒石酸钠二元二水合物是一种钠盐, 在分子生物学和细胞培养中用作缓冲液, 是酸性磷酸酶抑制剂, 增加秋水仙碱结合tubulin1率。

GP20944 TGFB1 Human TGF-β1 (transforming growth factor beta 1) is one of three closely related mammalian members of the large TGF-β1 superfamily that share a characteristic cystine knot structure.

GC34210 Pertuzumab (Anti-Human HER2, Humanized Antibody) Pertuzumab (Anti-Human HER2, Humanized Antibody), the first of a new class of agents designated as HER dimerisation inhibitors, is a humanised IgG1 monoclonal antibody (mAb) that sterically binds domain II of the erbB2 receptor.

GD80196 Mono[2-(perfluorooctyl)ethyl] Phosphate

GC61728 Dmt-2'-f-dc(ac) amidite

N-乙酰基-5'-O-(4,4-二甲氧基三苯甲基)-2'-脱氧-2'-氟胞苷-3'-(2-氰基乙基-N,N-二异丙基)亚磷酰胺,2'-F-Ac-dC Phosphoramidite; DMT-2′Fluoro-dC(ac) Phosphoramidite

Dmt-2'-f-dc(ac)amidite(2'-F-Ac-dCPhosphoramidite)是一种亚磷酰胺单体，可用于环嘌呤二核苷酸的制备。

GC30160 Cellulose carboxymethyl ether sodium

羧甲基纤维素钠,CMC-Na (MW 250000)

Cellulosearboxymethylethersodium是纤维素羧甲基醚的钠盐，常用作黏稠剂，糊料和阻隔剂。

GC49439 (±)11(12)-DiHET MaxSpec® Standard

(±)11,12-DiHETrE

A quantitative analytical standard guaranteed to meet MaxSpec^® identity, purity, stability, and concentration specifications

GD21541 Tris(dimethylsiloxy)phenylsilane

苯基三(二甲基硅氧烷基)硅烷

GC72280 3X HA Tag 3X HA Tag是一种生物活性肽，由9个氨基酸残基（YPYDVPDYA）重复3次构成。

GC63053 M-31850 M-31850 是一种有效，选择性和竞争性的 β-己糖胺酶 (β-hexosaminidase (Hex)) 抑制剂，对人 HexA 和 HexB 的 IC50 分别为 6.0 µM 和 3.1 µM。M-31850 还以 Ki 为 2.5 μM 来竞争性抑制 β-N-acetyl-D-hexosaminidase OfHex2。

GC52002 Emavusertib

CA-4948

An IRAK4 inhibitor

GC19600 Poly-L-lysine

多聚-L-赖氨酸

多聚左旋赖氨酸分子量3～7万

GC19186 GW4869 GW4869 is a noncompetitive neutral sphingomyelinase inhibitor with an IC50 of 1 uM.

GA23537 Suc-Ala-Ala-Pro-Val-AMC Suc-AAPV-AMC, substrate for human neutrophil elastase.

GC44298 N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid

N-乙酰-2,3-二脱氢-2-脱氧神经氨酸,Neu5Ac2en; DANA

An inhibitor of human neuraminidases

GC63005 Homodihydrocapsaicin I

高二氢辣椒素

Homodihydrocapsaicin I 是从辣椒果实中分离得到的一种辣椒素。

GC69899 SIRT6 activator 12q SIRT6 activator 12q 是有效的、选择性的和具有口服活性的 SIRT6 激活剂，对 SIRT1、SIRT2、SIRT3、SIRT5、SIRT6 的 IC50 值分别为 171.20、>200、>200、>200、0.58 μM。SIRT6 activator 12q 抑制细胞生长和迁移。SIRT6 activator 12q 诱导细胞凋亡 (Apoptosis) 和细胞周期停滞在 G2 期。SIRT6 activator 12q 显示出抗癌活性。

GC65549 Indisulam

N-(3-氯-1H-吲哚-7-基)-1,4-苯二磺酰胺,E 7070

A sulfonamide with anticancer activity

GC18824 CAY10465 A resveratrolbased aryl hydrocarbon receptor agonist

GC50600 Mitochondrial fusion promoter M1 Mitochondrial fusion promoter

GC14071 OSI-027

反式-4-[4-氨基-5-(7-甲氧基-1H-吲哚-2-基)咪唑并[5,1-F][1,2,4]三嗪-7-基]环己烷羧酸,ASP7486

MTORC1/ mTORC2 inhibitor

GC42327 4,9-Anhydrotetrodotoxin

4,9-anhydro-TTX

A selective blocker of Na_v1.6 channels

GB62109 Zinc(II) pivalate

特戊酸锌 Zinc pivalate 三甲基乙酸锌

GC34209 Rituximab (Anti-Human CD20 type I, Chimeric Antibody)

利妥昔单抗; Anti-Human CD20 type I, Chimeric Antibody

Rituximab is a human/murine, chimeric anti-CD20 monoclonal antibody with established efficacy, and a favorable and well-defined safety profile in patients with various CD20-expressing lymphoid malignancies[1].

GC19804 DNAase

脱氧核糖核酸酶,DNase I

DNA酶, ≥2000 Kunitz units/mg protein

GC12723 MRS 2279 Selective, high affinity competitive antagonist of the P2Y1 receptor

GP29011 IFN-α 2b, Human

GC14228 Propidium iodide

碘化丙啶; PI

Propidium iodide (PI) is a small red-fluorescent molecule that binds to DNA but cannot passively traverse into cells that possess an intact plasma membrane.

GP29008 IFN-γ, Mouse

Sharing 41% sequence identity with human Interferon gamma (hIFN--γ), mouse IFN gamma (mIFN--γ)is a macrophage-activating factor.

GC12574 ATPγS tetralithium salt

5'-(Γ-硫代)三磷酸腺苷四锂盐,Adenosine-5'-O-3-thiotriphosphate (tetralithium salt); Adenosine 5'-[γ-thio]triphosphate tetralithium salt

P2 purinergic receptor agonist