CTSE Human
目录号 : GP21506Cathepsin-E Human Recombinant
Sample solution is provided at 25 µL, 10mM.
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| Purity | Greaterthan 85% as determined by SDS-PAGE. | Source | Escherichia Coli. |
| Phycical Appearance | Sterile Filtered clear solution. | Shipping Condition | Shipped with Ice Packs. |
| Synonyms | CathepsinE; EC 3.4.23.34; CATE; Erythrocyte Membrane Aspartic Proteinase; Slow-MovingProteinase; EC 3.4.23. | ||
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSTESCSMD QSAKEPLINY LDMEYFGTIS IGSPPQNFTV IFDTGSSNLWVPSVYCTSPA CKTHSRFQPS QSSTYSQPGQ SFSIQYGTGS LSGIIGADQV SVEGLTVVGQ QFGESVTEPGQTFVDAEFDG ILGLGYPSLA VGGVTPVFDN MMAQNLVDLP MFSVYMSSNP EGGAGSELIF GGYDHSHFSG SLNWVPVTKQ AYWQIALDNMLWSVPTLTSC RMSPSPLTES PIPSAQLPTP YWTSWMECSS AAVAFKDLTS TLQLGPSGSW GMSSFDSFTQSLTVGITVWD WPQQSPKEGP CVCACLSDRP | ||
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. | ||
| Formulation | CTSE protein solution (1mg/ml) containing 20mM Tris-HClbuffer (pH 8.0), 0.4M urea and 10% glycerol. | ||
Cathepsin-E also known as CTSE is a gastric aspartyl protease whichfunctions as a disulfide-linked homodimer. CTSE belongs to the peptidase C1 family;furthermore it has specificity similar to pepsin A and cathepsin D. CTSE is anintracellular proteinase which does not seem to be involved in the digestion ofdietary protein and is found in theuppermost concentration in the surfaceof epithelial mucus-producing cells of the stomach. CTSE is the first aspartic proteinase expressed in the fetal stomach and is discovered in morethan half of gastric cancers. For that reason CTSE is an oncofetalantigen. In addition, transcript variants utilizing alternative polyadenylationsignals and two transcript variants encoding differentisoforms exist for this gene.
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.